Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New virus-based method opens wide range of options to treat various diseases

The ability to switch disease-causing genes on and off remains a dream for many physicians, research scientists and patients.

20 Jul 2016

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Using a robust model for Parkinson's disease, University of Alabama at Birmingham researchers and colleagues have discovered an interaction in neurons that contributes to Parkinson's disease, and they have shown that drugs now under development may block the process.

20 Jul 2016

Study provides more insight into effects of DBS in treatment of Alzheimer's disease

New findings published today by a team of researchers led by Dr. Andres Lozano at the Krembil Neuroscience Centre of Toronto Western Hospital have provided further insight into the effects of Deep Brain Stimulation (DBS) in the treatment of Alzheimer's disease.

20 Jul 2016

New research shows how toxic Alzheimer's protein spreads through the brain

A toxic Alzheimer's protein can spread through the brain--jumping from one neuron to another--via the extracellular space that surrounds the brain's neurons, suggests new research from Columbia University Medical Center.

19 Jul 2016

Postmenopausal estrogen supplement may not affect memory of healthy women

Contrary to popular belief, taking estrogen after menopause may not affect the memory and thinking abilities of healthy women no matter when the treatment is started.

19 Jul 2016

JAD announces recipient of 2016 Alzheimer Award

The Journal of Alzheimer's Disease is pleased to announce that Mark W. Bondi, PhD, ABPP/CN, Professor of Psychiatry at UC San Diego and Director of the Neuropsychological Assessment Unit at the VA San Diego Healthcare System, has been chosen as the recipient of the 2016 Alzheimer Award presented by the journal in recognition of his outstanding work on the development of a novel and promising method of staging preclinical Alzheimer's disease (AD) based on number of abnormal biomarkers that is predictive of progression to mild cognitive impairment (MCI) and AD.

15 Jul 2016

Genes linked to Alzheimer's disease may show effects on the brain from childhood

A gene associated with Alzheimer's disease and recovery after brain injury may show its effects on the brain and thinking skills as early as childhood, according to a study published in the July 13, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2016

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers have identified a new biological pathway involved in Alzheimer's disease. In experiments using fruit flies, blocking the pathway reduced the death of brain cells, suggesting that interfering with the pathway could represent a promising new strategy to treat the disease in human patients.

13 Jul 2016

Review highlights lack of consistent assessment tool to assess driving ability in people with Alzheimer's

No single assessment tool is able to consistently determine driving ability in people with Alzheimer's disease and mild cognitive impairment, a St. Michael's Hospital research review has found.

13 Jul 2016

17beta-Estradiol patch may help reduce Alzheimer's disease risk in newly postmenopausal women

Can estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estrogen via a skin patch had reduced beta-amyloid deposits, the sticky plaques found in the brains of people with Alzheimer's disease, a Mayo Clinic study published this month in the Journal of Alzheimer's Disease found.

13 Jul 2016

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.

12 Jul 2016

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

With more than 7.5 million new cases of Alzheimer’s disease a year, the race to find a vaccine and effective treatment for dementia is growing by the day.

12 Jul 2016

Aelan's researchers develop novel epigenetic biomarker for diagnosis of AD

Aelan Cell Technologies today announced the development of a novel epigenetic biomarker. An early human clinical feasibility study has indicated that serological tests using the biomarker alongside other proprietary components developed by Aelan's researchers could potentially help physicians diagnose Alzheimer's disease (AD).

12 Jul 2016

Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

A small phase I study provides molecular evidence that an FDA-approved drug for leukemia significantly increased brain dopamine and reduced toxic proteins linked to disease progression in patients with Parkinson's disease or dementia with Lewy bodies.

12 Jul 2016

Scientists create new eye technology for detecting Alzheimer's before onset of symptoms

Scientists may have overcome a major roadblock in the development of Alzheimer's therapies by creating a new technology to observe - in the back of the eye - progression of the disease before the onset of symptoms.

11 Jul 2016

Metallic molecule offers real-time monitoring of amyloid plaques in patients with Alzheimer's

A metallic molecule being studied at Rice University begins to glow when bound to amyloid protein fibrils of the sort implicated in Alzheimer's disease. When triggered with ultraviolet light, the molecule glows much brighter, which enables real-time monitoring of amyloid fibrils as they aggregate in lab experiments.

11 Jul 2016

Diversity of gut bacteria may affect brain health

The surprising and potentially wide-ranging effects that the levels and diversity of bacteria living in the gut have on overall human health, inflammation, and specifically brain health are the focus of a provocative interview with Dr. David Perlmutter in Alternative and Complementary Therapies, a journal from Mary Ann Liebert, Inc., publishers.

11 Jul 2016

New study identifies four subtypes of human insulin producing beta cells involved in diabetes

A new study led by nationally prominent stem cell scientist Markus Grompe, M.D., has determined the existence of at least four separate subtypes of human insulin producing beta cells that may be important in the understanding and treatment of diabetes. The findings were published online today in the journal Nature Communications.

11 Jul 2016

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Traumatic brain injury (TBI) with a loss of consciousness (LOC) may be associated with later development of Parkinson's disease but not Alzheimer's disease or incident dementia, according to a study conducted at the Icahn School of Medicine at Mount Sinai and the University of Washington School of Medicine.

11 Jul 2016

Scientists reveal how common symptomless condition can develop into myeloma

Researchers from the University of Birmingham and hospitals across the West Midlands have revealed how a common symptomless condition can develop into the blood cancer myeloma.

11 Jul 2016

Alzheimer's Disease News and Research

Further Reading

New virus-based method opens wide range of options to treat various diseases

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Study provides more insight into effects of DBS in treatment of Alzheimer's disease

New research shows how toxic Alzheimer's protein spreads through the brain

Postmenopausal estrogen supplement may not affect memory of healthy women

JAD announces recipient of 2016 Alzheimer Award

Genes linked to Alzheimer's disease may show effects on the brain from childhood

Researchers discover new biological pathway involved in Alzheimer's disease

Review highlights lack of consistent assessment tool to assess driving ability in people with Alzheimer's

17beta-Estradiol patch may help reduce Alzheimer's disease risk in newly postmenopausal women

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

Aelan's researchers develop novel epigenetic biomarker for diagnosis of AD

Leukemia drug increases brain dopamine, lowers toxic proteins linked to Parkinson's or dementia

Scientists create new eye technology for detecting Alzheimer's before onset of symptoms

Metallic molecule offers real-time monitoring of amyloid plaques in patients with Alzheimer's

Diversity of gut bacteria may affect brain health

New study identifies four subtypes of human insulin producing beta cells involved in diabetes

TBI with LOC linked to late-life neurodegeneration but not Alzheimer's disease

Scientists reveal how common symptomless condition can develop into myeloma

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