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Oral GLP-1 drug orforglipron achieves significant weight loss in global trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase III clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions

18 Sep 2025

Genomic studies reveal human influence on mosquito evolution and disease spread

Two of the world's deadliest mosquito vectors – Aedes aegypti and Anopheles funestus – have evolved, spread, and adapted in ways that complicate global disease control, two studies show.

18 Sep 2025

New trial demonstrates efficacy of tirzepatide in children and adolescents with type 2 diabetes

New research shows that that the diabetes/obesity medication tirzepatide can cause clinically meaningful improvements in blood sugar control and weight loss in children and adolescents with type 2 diabetes aged 10-17 years whose diabetes and weight are inadequately controlled with an existing treatment regimen of metformin, insulin, or both.

18 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Evening meals hold the key to morning glucose control in prediabetes

The way glucose is regulated at night plays a key role in fasting glucose levels the next morning, when blood sugar is expected to be at its lowest.

18 Sep 2025

New class of antibiotics shows potent activity against multidrug-resistant bacteria

Scientists at the University of Liverpool, working with international collaborators, have discovered Novltex, a groundbreaking new class of antibiotics with potent activity against some of the world's most dangerous multidrug-resistant (MDR) bacteria.

18 Sep 2025

Real-time blood testing shows promise for preventing maternal deaths from hemorrhage

Postpartum hemorrhage, severe bleeding after childbirth, is a leading cause of maternal mortality around the world.

18 Sep 2025

Nursing researchers explore new ways to improve the quality of methadone treatment

Researchers at the University of Arizona College of Nursing are testing an intervention to reduce staff stress and improve methadone patient treatment retention for opioid use disorder thanks to a $4.5 million grant from the National Institute on Drug Abuse, a division of the National Institutes of Health.

18 Sep 2025

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

A new study has found that prompt administration of opioid pain relief in emergency departments reduces the likelihood of hospitalization for children with sickle cell disease, according to findings published in JAMA Pediatrics.

18 Sep 2025

Genetic study reveals how Anopheles funestus adapts to malaria control

New research into the genetics of Anopheles funestus (An. funestus), one of the most neglected but prolific malaria-transmitting mosquitoes in Africa, has revealed how this species is evolving in response to malaria control efforts.

18 Sep 2025

Mobile app improves reporting of suspected adverse drug reactions in Uganda

Results from a ground-breaking new trial published in The Lancet Global Health show that a mobile application, Med Safety, improved the reporting of suspected adverse drug reactions (ADRs) by healthcare workers in Uganda.

18 Sep 2025

Clinical trial reveals encouraging results for apitegromab in spinal muscular atrophy

A new clinical trial has revealed encouraging results for a muscle-targeting therapy aimed at improving motor function in children and adolescents with spinal muscular atrophy, according to a study published in The Lancet Neurology.

18 Sep 2025

Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

Investigational drug reduces hot flashes and night sweats for post-menopausal women

The investigational drug elinzanetant significantly reduces hot flashes and night sweats for post-menopausal women, a large, international clinical trial has found.

18 Sep 2025

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer's disease.

18 Sep 2025

Cholesterol control improves but cardiovascular disease still increases in Mexico

Despite improved statin use and cholesterol control, cardiovascular disease risk rose in Mexico between 2016 and 2023, according to a study being presented at ACC Latin America 2025 that used region-specific tools to more accurately predict the local disease burden.

18 Sep 2025

Music therapy improves patient experience and outcomes in the cardiac ICU

Music therapy could significantly reduce heart rate, blood pressure and patient–ventilator asynchronies for patients admitted to the cardiac intensive care unit (ICU), according to research being presented at ACC Latin America 2025 taking place September 18-20 in Mexico City.

18 Sep 2025

Study reveals bidirectional relationship between long COVID and menstrual disorders

Women suffering from long COVID have a greater risk of experiencing abnormal uterine bleeding.

18 Sep 2025

New study uncovers why dispersed glioblastoma cells are more dangerous

A new study, led by researchers at Sylvester Comprehensive Cancer Center part of the University of Miami Miller School of Medicine, captured details of glioblastoma that had never before been seen and revealed a surprise finding: Glioblastoma cells that "cluster" together with other cells of the same type are less deadly than those that disperse from these clusters.

18 Sep 2025

Medicine News and Research

Oral GLP-1 drug orforglipron achieves significant weight loss in global trial

Genomic studies reveal human influence on mosquito evolution and disease spread

New trial demonstrates efficacy of tirzepatide in children and adolescents with type 2 diabetes

PANoptosis emerges as a promising strategy against liver cancer

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

Evening meals hold the key to morning glucose control in prediabetes

New class of antibiotics shows potent activity against multidrug-resistant bacteria

Real-time blood testing shows promise for preventing maternal deaths from hemorrhage

Nursing researchers explore new ways to improve the quality of methadone treatment

Timely opioid treatment lowers hospitalizations in children with sickle cell disease

Genetic study reveals how Anopheles funestus adapts to malaria control

Mobile app improves reporting of suspected adverse drug reactions in Uganda

Clinical trial reveals encouraging results for apitegromab in spinal muscular atrophy

Muscle hormone FGF21 linked to longer survival in ALS

Investigational drug reduces hot flashes and night sweats for post-menopausal women

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Cholesterol control improves but cardiovascular disease still increases in Mexico

Music therapy improves patient experience and outcomes in the cardiac ICU

Study reveals bidirectional relationship between long COVID and menstrual disorders

New study uncovers why dispersed glioblastoma cells are more dangerous

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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