Liver News and Research

RSS

Study shows how drinking patterns reprogram circadian metabolism in the liver

Drinking alcohol is a widespread habit in modern society and can have serious metabolic consequences. Recent studies have uncovered the interplay between nutrition, metabolism and circadian rhythms. But, until now, little has been done to understand the effects of alcohol consumption on circadian metabolism.

22 Nov 2019

Predicting opioid-related problems among cancer survivors

Opioids play an important role in how cancer patients manage pain, but the ongoing opioid epidemic has raised concerns about their potential for abuse.

22 Nov 2019

Recently discovered protein may play key role in obesity and metabolic disease

With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism.

21 Nov 2019

One surgery to tackle two life threatening diseases

Juan Cueto did not feel sick, but he was losing weight rapidly and was devastated with the knowledge that he had two life threatening diseases, cancer and a liver disease.

20 Nov 2019

Impaired gene expression may influence aging via altered cellular metabolism

Throughout history, humans have been obsessed with finding a way to prevent aging and prolong life. Although the mechanisms have long eluded us, modern science is revealing more and more about the aging process. Now, researchers from Japan have uncovered new information about the genetic processes that may trigger age-related disorders, including low energy production and low cellular growth.

20 Nov 2019

Breakthrough therapy could improve health and survival in people with cystic fibrosis

Researchers at the Children's Hospital Colorado Breathing Institute, one of the largest cystic fibrosis clinical care centers in the U.S., are part of a Therapeutics Development Network that oversaw clinical trials leading to FDA approval of TRIKAFTA, a new, highly-effective CF treatment for people with CF 12 years of age and older.

20 Nov 2019

Prior DDT exposure may contribute to diabetes risk among Asian Indian immigrants

Previous exposure to the pollutant DDT may contribute to the risk of diabetes among Asian Indian immigrants to the United States, according to a study from the University of California, Davis.

20 Nov 2019

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

The first two clinical trials for CRISPR-based treatments for inherited blood disorders have been successful.

20 Nov 2019

Prior exposure to pollutants linked to increased risk of diabetes in Indian immigrants

In 2004, the United Nations Stockholm Convention banned the production and use of many persistent organic pollutants, such as dichlorodiphenyltrichloroethane and polychlorinated biphenyls.

20 Nov 2019

Intermittent fasting – not just a fad for cardiac patients

A new study suggests patients with cardiac catheterization have a longer lifespan if they carry out intermittent fasting.

20 Nov 2019

New California law may expand use of HIV prevention drugs, with caveats

Kellen Willhite was 24 when he learned he'd been exposed to HIV. What followed was, as he describes it, a second trauma: trying to obtain the drugs that could save him before it was too late.

20 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Daltonics 20 Nov 2019

Cell factors decide if a cancer grows or dies, says new study

A new study published today in the journal Cell Reports by scientists at the German Cancer Research Center (DKFZ) shows that the direction taken by a cancer cell depends on the configuration of the cell itself as well as the activation of a universal cancer cell receptor called CD95.

19 Nov 2019

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

The liver performs several critical functions including filtering blood, detoxifying chemicals and metabolizing drugs.

19 Nov 2019

Scientists grow complex organoids in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

19 Nov 2019

New technology may offer alternative means of profiling tissues

Current cancer treatment courses often begin with tissue biopsies. Biopsies, however, which involve the physical resection of a small tissue sample, can lead to localized tissue injury, bleeding, inflammation, and stress, as well as increased risk of metastasis.

19 Nov 2019

Pioneering scientist wins 2019 Foulkes Foundation Medal for contributions to biomedical science

Professor Muzlifah Haniffa from Newcastle University and the Wellcome Sanger Institute has won the 2019 Foulkes Foundation Medal for her ground-breaking contributions to biomedical science, it was announced today [Tuesday 19 November, 2019].

18 Nov 2019

New drug combo may improve pancreatic cancer therapy

A new study by scientists at Sanford Burnham Prebys Medical Discovery Institute have discovered a combination of two cancer-fighting drugs that successfully worked on pancreatic tumor in mice, shrinking them significantly, and paving the way for a speedy clinical trial designed to test their efficacy in humans.

18 Nov 2019

Cancer drug shows promise in treating metabolic syndrome

Metabolic syndrome is a group of health problems characterized by the presence of elevated blood pressure, increased levels of triglycerides, high blood sugar, excess body fat around the waist, and obesity. If it’s left untreated, it can increase the risk of heart disease, stroke, and type 2 diabetes. Usually, treating metabolic syndrome involves targeting individual risk factors and modifying lifestyle practices.

18 Nov 2019

Experimental drug found to be effective at reducing bad cholesterol

Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients already taking the maximum dose of statin drugs, according to data of the ORION-10 trial presented Saturday, Nov. 16, at the American Heart Association's Scientific Sessions 2019.

17 Nov 2019