Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

More than 25 million Americans have diabetes, yet as many as 60 percent of type 2 diabetes patients do not follow treatment plans prescribed by their healthcare provider and about 50 percent fail to meet treatment recommendations for control of blood glucose levels.

26 Nov 2013

High intake of sugar-sweetened beverages reports increased risk of endometrial cancer

Postmenopausal women who consumed sugar-sweetened beverages were more likely to develop the most common type of endometrial cancer compared with women who did not drink sugar-sweetened beverages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

25 Nov 2013

Researchers discover how type 2 diabetes drug metformin actually works

Researchers from St. Vincent's Institute of Medical Research in Melbourne, Australia, in collaboration with researchers at McMaster University in Canada, are reportedly the first to discover how the type 2 diabetes drug metformin actually works, providing a molecular understanding that could lead to the development of more effective therapies. Mass spectrometry technologies from AB SCIEX, a global leader in analytical technologies, played a critical role in the analysis that led to this breakthrough finding.

25 Nov 2013

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

Janssen-Cilag International NV announced today that the European Commission has approved INVOKANA (canagliflozin) in the European Union for the treatment of adults with type 2 diabetes mellitus, to improve glycaemic control[1]. Canagliflozin is an oral, once-daily medication, which belongs to a new class of medications called sodium glucose co-transporter 2 (SGLT2) inhibitors.

23 Nov 2013

Nanotechnology-based technique: A painless method for maintaining healthy blood sugar levels

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections - rather than using needles to give themselves multiple insulin injections each day.

22 Nov 2013

Targeting single enzyme in the obese could help prevent and treat diabetes

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to mouse studies done by researchers at Columbia University Medical Center. The findings were published today in the online edition of Cell Metabolism.

22 Nov 2013

People who consume nuts daily are 20% less likely to die

In the largest study of its kind, people who ate a daily handful of nuts were 20 percent less likely to die from any cause over a 30-year period than were those who didn't consume nuts, say scientists from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and the Harvard School of Public Health.

21 Nov 2013

New $3.4 million NIH grant to fund artificial pancreas projects

A high-tech project to turn an ordinary smart phone into an artificial pancreas that could transform the lives of people with type 1 diabetes has received a $3.4 million grant from the National Institutes of Health.

19 Nov 2013

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Researchers explore how certain molecular signaling pathways control aging across all species

Fruit flies are notoriously short-lived but scientists interested in the biology of aging in all animals have begun to understand why some fruit flies live longer than others. They have documented a direct association between insulin and life span, for example, and have observed a tradeoff between prolific reproduction and longevity. A new study, which may have broad implications across species, ties those findings more closely together by tracing an insulin signaling cascade through to protein quality control in muscle tissue and shortened life span.

18 Nov 2013

Measuring BMI can help predict diabetic patient's risk for heart disease

Researchers from the Intermountain Medical Center Heart Institute, in collaboration with researchers from Johns Hopkins University and the National Institutes of Health, have discovered a simple way to further predict a diabetic patient's risk for heart disease: by measuring their body mass index or BMI.

17 Nov 2013

New smartphone app aims to help diabetic young people keep safe when drinking alcohol

A free smartphone application (app) aimed at younger people, which puts important information about the condition in their hands wherever they are, has notched up more than 1,100 downloads in its first year.

16 Nov 2013

Study: Surgical weight loss may be able to reverse the effects of aging

Stanford University researchers say surgical weight loss may turn back the effects of aging at a genetic level, in the first study* of its kind presented here during ObesityWeek 2013, the largest international event focused on the basic science, clinical application and prevention and treatment of obesity.

16 Nov 2013

Good quality care for young people with type-1 diabetes unevenly distributed in Ireland

New research launched today to coincide with World Diabetes Day which takes place tomorrow, 14th November 2013 revealed that good quality care for young people with type-1 diabetes is unevenly distributed throughout Ireland.

15 Nov 2013

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Researchers at Texas Woman's University have shown that a diterpene geranylgeraniol found in linseed oil, Cedrela toona wood oil, sucupira branca fruit oil and more recently, annatto seed oil, suppressed the viability of human DU145 prostate carcinoma cells via cell cycle arrest at the G1 phase and the initiation of apoptosis.

14 Nov 2013

Study identifies patterns of brain activity associated with eating disorders

A growing body of evidence shows the impact of diet on brain function, and identifies patterns of brain activity associated with eating disorders such as binge eating and purging. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

14 Nov 2013

Single dose of intranasal insulin can help improve cognitive function in diabetes patients

In recent years, the link between type 2 diabetes and dementia has become widely recognized. Older individuals with diabetes develop Alzheimer's disease at an earlier age, and are more likely to develop vascular dementia than people who do not have diabetes.

14 Nov 2013

Stem cells from Wolfram syndrome patients used to elucidate beta-cell failure pathway in diabetes

Scientists from the New York Stem Cell Foundation Research Institute and Columbia University Medical Center have used stem cells created from the skin of patients with a rare form of diabetes—Wolfram syndrome—to elucidate an important biochemical pathway for beta-cell failure in diabetes. The findings by Linshan Shang and colleagues were published today in Diabetes.

13 Nov 2013

Study highlights disparities in access to diabetes treatment in European countries

Hundreds of thousands of people living with diabetes in Europe do not have access to the treatment they need, putting their health at risk. These are the initial findings of a study by the International Diabetes Federation Europe on Access to Quality Medicines and Medical Devices for Diabetes Care in Europe.

13 Nov 2013

Scientists use new technology to study whole genome to find the cause of genetic disease

For the first time, scientists have used new technology which analyses the whole genome to find the cause of a genetic disease in what was previously referred to as "junk DNA".

11 Nov 2013

Insulin News and Research

Further Reading

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

High intake of sugar-sweetened beverages reports increased risk of endometrial cancer

Researchers discover how type 2 diabetes drug metformin actually works

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

Nanotechnology-based technique: A painless method for maintaining healthy blood sugar levels

Targeting single enzyme in the obese could help prevent and treat diabetes

People who consume nuts daily are 20% less likely to die

New $3.4 million NIH grant to fund artificial pancreas projects

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Researchers explore how certain molecular signaling pathways control aging across all species

Measuring BMI can help predict diabetic patient's risk for heart disease

New smartphone app aims to help diabetic young people keep safe when drinking alcohol

Study: Surgical weight loss may be able to reverse the effects of aging

Good quality care for young people with type-1 diabetes unevenly distributed in Ireland

Study shows that geranylgeraniol suppresses viability of human DU145 prostate carcinoma cells

Study identifies patterns of brain activity associated with eating disorders

Single dose of intranasal insulin can help improve cognitive function in diabetes patients

Stem cells from Wolfram syndrome patients used to elucidate beta-cell failure pathway in diabetes

Study highlights disparities in access to diabetes treatment in European countries

Scientists use new technology to study whole genome to find the cause of genetic disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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