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Enhancing viral therapy for resistant cancers with a metabolite-drug

When a cancer cell doesn't respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying 'troops' in the form of viral agents that are specifically engineered to target and eliminate cancer cells.

28 Jun 2024

Google searches reveal growing interest in microdosing amid changing drug policies

Loosening local, state and federal regulations on cannabis and psychedelics has increased Americans' interest in microdosing, according to a study from researchers at the University of California San Diego.

28 Jun 2024

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes.

28 Jun 2024

Gene therapy milestone at SickKids offers hope for children with SPG50 neurodegenerative disorder

When Michael Pirovolakis received an individualized gene therapy in a single-patient clinical trial at The Hospital for Sick Children (SickKids) in March 2022, the course of his condition was dramatically altered.

28 Jun 2024

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

A team of researchers led by Penn Medicine will investigate the link between traumatic brain injuries (TBI) and Alzheimer's disease and related dementias (ADRD) over the next five years with a $10 million grant from the National Institute of Neurological Disorders and Stroke (NINDS).

28 Jun 2024

Remote strategy-based intervention shows promise for individuals with memory impairments caused by MS

A pilot study shows promise for a new treatment option for individuals with memory impairments caused by multiple sclerosis (MS).

28 Jun 2024

New study links psoriasis severity to skin microbiome dysbiosis

A multi-omics analysis of host-microbe interactions in psoriasis.

28 Jun 2024

New techniques revolutionize muscle strength assessment

Understanding individual muscle strength is crucial for optimizing physical therapy and enhancing athletic performance. Traditional methods, however, often fall short in precision. The newly introduced technique by Zuming Xiao and colleagues from the Beijing Institute of Technology and Shenyang Sport University bridges this gap by integrating direct muscle strength measurements with dynamic simulations.

28 Jun 2024

Study uncovers role of Y chromosome loss in transthyretin cardiac amyloidosis

Researchers at Boston Medical Center (BMC) and Boston University (BU) Chobanian & Avedisian School of Medicine, in collaboration with an international team of scientists, shared findings from a new study published in the American Heart Association journal, Circulation: Heart Failure that explores a common cause of heart disease in older men called transthyretin cardiac amyloidosis (ATTR-CA).

27 Jun 2024

CHARMs: A new hope for prion disease therapy

Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades.

27 Jun 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

27 Jun 2024

Study identifies mechanism that impedes the effectiveness of melanoma therapies

In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance.

27 Jun 2024

Study reveals mental health challenges among LGBTQ+ farmers in the U.S.

LGBTQ+ people involved in U.S. farm work are over three times more likely to experience depression and suicidal intent and about two and a half times more likely to experience anxiety than the general population.

27 Jun 2024

Rate of young women getting sterilized doubled after ‘Roe’ was overturned

Sophia Ferst remembers her reaction to learning that the Supreme Court had overturned Roe v. Wade: She needed to get sterilized.

27 Jun 2024

Researchers identify key players in abnormal bone differentiation

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease caused by a mutation in the gene IFITM5.

27 Jun 2024

Evaluating CGM accuracy and benefits in non-diabetic populations

A new narrative review led by researchers at UCL and Birmingham Children's Hospital has found there is a lack of evidence to demonstrate the effective use of continuous glucose monitors (CGMs) in people not living with diabetes (PNLD).

27 Jun 2024

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Combining exercise with GLP-1 RA liraglutide results in significant weight loss while preserving bone health in adults with obesity.

27 Jun 2024

Experts call for better information and treatments for post-orgasmic illness syndrome

A study in the "International Journal of Impotence Research" reveals that sexual medicine experts find current information on post-orgasmic illness syndrome (POIS) inadequate, often referring patients for psychotherapy or prescribing antihistamines with limited symptom improvement.

26 Jun 2024

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

New research led by UCLA Health confirms that both Tai Chi and cognitive behavioral therapy can reduce insomnia in breast cancer survivors but also may provide additional health benefits by reducing inflammation and bolstering anti-viral defenses.

26 Jun 2024

Therapy News and Research

Enhancing viral therapy for resistant cancers with a metabolite-drug

Google searches reveal growing interest in microdosing amid changing drug policies

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Gene therapy milestone at SickKids offers hope for children with SPG50 neurodegenerative disorder

Penn researchers aim to uncover the underlying biological mechanisms of TBI-related neurodegeneration

Remote strategy-based intervention shows promise for individuals with memory impairments caused by MS

New study links psoriasis severity to skin microbiome dysbiosis

New techniques revolutionize muscle strength assessment

Study uncovers role of Y chromosome loss in transthyretin cardiac amyloidosis

CHARMs: A new hope for prion disease therapy

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Study identifies mechanism that impedes the effectiveness of melanoma therapies

Study reveals mental health challenges among LGBTQ+ farmers in the U.S.

Rate of young women getting sterilized doubled after ‘Roe’ was overturned

Researchers identify key players in abnormal bone differentiation

Evaluating CGM accuracy and benefits in non-diabetic populations

Study reveals exercise and GLP-1 RA combination preserves bone health during weight loss

Experts call for better information and treatments for post-orgasmic illness syndrome

Tai Chi and cognitive behavioral therapy can reduce insomnia, inflammation in breast cancer survivors

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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