Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Protective effect of estrogen in women with NASH against development of severe fibrosis

New research suggests that estrogen protects women with nonalcoholic steatohepatitis (NASH) from severe liver fibrosis. According to the study published online in Hepatology, a journal of the American Association for the Study of Liver Diseases, men are at higher risk of more severe fibrosis compared to women prior to menopause, but liver fibrosis severity is similar in men and post-menopausal women.

30 Oct 2013

DPP-4 inhibitors may reduce risk of autoimmune diseases

Dipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these patients, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

New study finds association between OSA and subclinical myocardial injury

Obstructive sleep apnea is known to be associated with an increased incidence of cardiovascular disease. Now a new study indicates that OSA is associated with subclinical myocardial injury, as indicated by increased high sensitivity troponin T levels. Elevated hs-TnT levels are predictive of both coronary heart disease and heart failure in the general population.

25 Oct 2013

Study: Investigational drug shows promise against pancreatic cancer

An investigational drug that disrupts tumor blood vessels shows promise against a rare type of pancreatic cancer, scientists at Albert Einstein College of Medicine of Yeshiva University have found. Their results were presented October 20 during a poster session at an international cancer conference.

25 Oct 2013

Researchers discover novel genetic cause of severe obesity

Researchers from the University of Cambridge have discovered a novel genetic cause of severe obesity which, although relatively rare, demonstrates for the first time that genes can reduce basal metabolic rate - how the body burns calories.

25 Oct 2013

Biolinerx Inks In-License Agreement With Israeli Institutions For Type 1 Diabetes Treatment

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24 Oct 2013

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Research from Boston University School of Medicine suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

24 Oct 2013

Biolinerx In-Licenses Type 1 Diabetes Treatment With Israel Institutions

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23 Oct 2013

Inflammation causally linked to functional decline in aging

Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer's, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan - that portion of our lives spent relatively free of serious illness and disability.

23 Oct 2013

Fatty acid entry into cells happens by diffusion

The current global epidemic of obesity-linked diabetes and its associated consequences -cardiovascular, neurological and renal diseases - is a growing public health problem for which therapeutic options are limited.

23 Oct 2013

Study evaluates role of enteroviruses in human type 1 diabetes

Type 1 diabetes is a disease caused by the destruction of the insulin-producing cells in the pancreas. It is often diagnosed in childhood and requires life-long treatment with daily insulin injections. It is associated with an increased risk for long-term complications which decrease the quality of life and average life-expectancy.

23 Oct 2013

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

Novo Nordisk today announced that Health Canada has approved Levemir® FlexTouch®, a disposable prefilled insulin pen containing Levemir® (insulin detemir). Levemir® FlexTouch® has been designed to improve ease of use for insulin administration and to help decrease barriers to good treatment adherence for Canadians living with type 1 and type 2 diabetes mellitus (diabetes).

19 Oct 2013

High-intensity interval training with Mediterranean diet counselling 'supersizes' heart health

Lifestyle programs focused on high-intensity interval training combined with nutritional counselling on the Mediterranean diet have shown dramatic results for improving the heart health of people with abdominal obesity, finds a study released at the Canadian Cardiovascular Congress.

18 Oct 2013

Study aims to identify age-related changes in metabolic pathways

Have you ever wondered why young children can eat bags of Halloween candy and feel fine the next day - compared to adults who experience all sorts of agony following the same junk food binge? Evolution and a gene called Foxo may be to blame. Working in fruit flies, scientists at the Buck Institute have identified a mechanism that helps the flies adapt to changes in diet when they're young; they've discovered that same mechanism gets misregulated as the flies age, disrupting metabolic homeostasis, or balance.

16 Oct 2013

Evidence less consistent for high blood sugar, insulin treatment and oral agents

Charles H. Hennekens, M.D., Dr.P.H., the first Sir Richard Doll professor and senior academic advisor to the dean in the Charles E. Schmidt College of Medicine at Florida Atlantic University was senior author of a consensus statement from the American Association of Clinical Endocrinologists on diabetes and cancer, which was just published in Endocrinology Practice.

16 Oct 2013

Researchers develop innovative 3D method to grow miniature pancreas from progenitor cells

An international team of researchers from the University of Copenhagen have successfully developed an innovative 3D method to grow miniature pancreas from progenitor cells. The future goal is to use this model to help in the fight against diabetes. The research results has just been published in the scientific journal Development.

16 Oct 2013

Mayo Clinic: Physical activity is associated with reduced risk of esophageal cancer

Physical activity is associated with a reduced risk of esophageal cancer, according to a new study presented by Mayo Clinic researchers at the American College of Gastroenterology's Annual Scientific Meeting, Oct. 11-16, in San Diego.

15 Oct 2013

Men who didn't exercise more likely to have dysfunctional HDL

There's no question that high levels of good cholesterol-also known as high-density lipoprotein -seem to be protective against heart disease. Rather than depositing fat into the blood vessels the way the "bad" cholesterol (low-density lipoprotein does, HDL appears to carry cholesterol away from blood vessels to the liver. From there, the liver processes it for removal from the body.

13 Oct 2013

UCLA, Takeda to study how disruption of circadian rhythms promotes type 2 diabetes

Millions of individuals worldwide are exposed to shift work and numerous environmental conditions that disturb circadian clock function and disrupt normal circadian rhythms. Environmental conditions associated with disrupted circadian rhythms greatly increase the risk for development of type 2 diabetes and metabolic syndrome and also hinder the treatment and management of hyperglycemia in existing patients with diabetes.

13 Oct 2013

New less invasive surgical method paves way for development of efficient anti-obesity therapies

Bariatric surgeries, such as a gastric bypass, are currently the most effective anti-obesity therapies. They also lead to a reduced insulin resistance. However, the pitfall of these surgical interventions is that they are highly invasive and often permanent procedures.

11 Oct 2013

Insulin News and Research

Further Reading

Protective effect of estrogen in women with NASH against development of severe fibrosis

DPP-4 inhibitors may reduce risk of autoimmune diseases

New study finds association between OSA and subclinical myocardial injury

Study: Investigational drug shows promise against pancreatic cancer

Researchers discover novel genetic cause of severe obesity

Biolinerx Inks In-License Agreement With Israeli Institutions For Type 1 Diabetes Treatment

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Biolinerx In-Licenses Type 1 Diabetes Treatment With Israel Institutions

Inflammation causally linked to functional decline in aging

Fatty acid entry into cells happens by diffusion

Study evaluates role of enteroviruses in human type 1 diabetes

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

High-intensity interval training with Mediterranean diet counselling 'supersizes' heart health

Study aims to identify age-related changes in metabolic pathways

Evidence less consistent for high blood sugar, insulin treatment and oral agents

Researchers develop innovative 3D method to grow miniature pancreas from progenitor cells

Mayo Clinic: Physical activity is associated with reduced risk of esophageal cancer

Men who didn't exercise more likely to have dysfunctional HDL

UCLA, Takeda to study how disruption of circadian rhythms promotes type 2 diabetes

New less invasive surgical method paves way for development of efficient anti-obesity therapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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