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Pocket-size device helps people living with HIV remember their medicine

In a study from Johns Hopkins, a pocket-size device giving electronic-voice reminders to "take your medicine" proves to be a success for people living with HIV whose memory is slightly impaired by the virus.

20 Sep 2005

PUMA protein offers critical insights for developing new anti-cancer drugs

The discovery of how the activities of the protein p53 initiate signals that trigger cell suicide offers critical insights for developing new anti-cancer drugs, according to investigators from St. Jude Children's Research Hospital.

20 Sep 2005

Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Researchers determine the sequence in which the malaria parasite disperses from the red blood cells it infects

Researchers at the National Institute of Child Health and Human Development have determined the sequence in which the malaria parasite disperses from the red blood cells it infects. The National Institute of Child Health and Human Development is one of the Institutes comprising the National Institutes of Health.

19 Sep 2005

Discovery that protein CD38 interrupts an interaction between the AIDS virus and its point of entry into cells

Cornell University researchers have discovered the 3-D crystal structure of a protein, human CD38, which may lead to important discoveries about how cells release calcium - a mineral used in almost every cellular process.

19 Sep 2005

Carbon nanotubes as transport agents for antimycotics (antifungal agents)

Putting pharmaceutical agents into the body isn't hard, but getting them into targeted areas can be problematic. If drugs aren't taken up by a large enough proportion of cells, a suitable "transport agent" must be used.

19 Sep 2005

Study points to importance of MYC gene in cancer progression

The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of the breast, ovaries, lung, prostate, and skin, as well as leukemias and lymphomas.

19 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Scientists have discovered a new and potent anti-cancer compound in beans

Scientists have discovered a new and potent anti-cancer compound in everyday food. The collaborative study led by UCL (University College London) shows that the compound - inositol pentakisphosphate - found in beans, nuts and cereals inhibits a key enzyme (phosphoinositide 3-kinase) involved in tumour growth.

19 Sep 2005

New research will play a major role in improving the future of breast cancer treatment

Cancer specialists at University of East Anglia have discovered that several 'ADAMTS' genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for the development of 'smart' drugs tailored to treat individual patients' tumours.

19 Sep 2005

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

The study found that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine.

19 Sep 2005

46,000 crack cocaine users aged 15-44 in London

Researchers believe there could be 46,000 crack cocaine users aged 15-44 in London, suggesting one in every hundred young adult Londoners could be a user.

19 Sep 2005

Researchers selectively knock out memory associations connected with receiving cocaine

Addicts crave drugs and suffer relapse not just because of the alluring high of drugs, but also because they are compelled by the powerful, haunting memory associations with the environment surrounding their drug taking. Thus, treatments that could eliminate those memory associations could prove effective in treating addiction, researchers believe.

19 Sep 2005

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

...who have never taken them before (so-called 'treatment-naive patients'), which could have disastrous consequences, says a team of researchers in Uganda.

19 Sep 2005

Cost-cutting strategy employed by HMOs for 15 years is simply not working

With rising concern over the cost of the new Medicare prescription drug benefit program – going into effect January, 2006 and estimated to cost $593 billion over the next decade – a new UCSF study reveals that a key cost-cutting strategy employed by HMOs for 15 years is simply not working.

19 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

Drugs News and Research

Pocket-size device helps people living with HIV remember their medicine

PUMA protein offers critical insights for developing new anti-cancer drugs

Salicylate an active metabolite of aspirin - weakens lipid membranes

Researchers determine the sequence in which the malaria parasite disperses from the red blood cells it infects

Discovery that protein CD38 interrupts an interaction between the AIDS virus and its point of entry into cells

Carbon nanotubes as transport agents for antimycotics (antifungal agents)

Study points to importance of MYC gene in cancer progression

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Scientists have discovered a new and potent anti-cancer compound in beans

New research will play a major role in improving the future of breast cancer treatment

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

46,000 crack cocaine users aged 15-44 in London

Researchers selectively knock out memory associations connected with receiving cocaine

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

Cost-cutting strategy employed by HMOs for 15 years is simply not working

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

Screening test for cells that activate immune system

Generex Biotechnology granted Canadian patent

Nuclear receptor proteins could change anti-inflammatory treatments

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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