Immune System News and Research

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Daily peanut exposure shows success in treating toddler allergies

Researchers at Karolinska Institutet have successfully treated children aged 1–3 years with peanut allergies. The children slowly became accustomed to eating peanuts by consuming small amounts of them daily, which were gradually increased over time.

6 May 2026

Blood-based biomarkers identified for early inflammatory breast cancer diagnosis

Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified specific blood-based genomic biomarkers that distinguish inflammatory breast cancer from other subtypes, providing a new and less invasive method for early diagnosis, disease progression monitoring and treatment development for patients with this aggressive disease.

6 May 2026

USF researchers develop AI framework to predict immune system responses

Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments.

6 May 2026

Tumor splicing burden predicts treatment response in kidney cancer

Researchers at City of Hope® and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC).

5 May 2026

Study highlights breakthrough in overcoming diminishing returns of sequential IBD therapies

For patients with Crohn's disease or ulcerative colitis who have exhausted other treatment options, a new combination therapy is showing results that offer hope for one of medicine's most treatment-resistant populations, according to findings from two studies to be presented today at Digestive Disease Week® (DDW) 2026.

5 May 2026

New genomic study tracks rare blood disease in children

Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome (MDS) and leukemia. A study led by scientists at St. Jude Children's Research Hospital, with multiple collaborating institutions, used state-of-the-art genomic techniques to profile 619 children and adults with aplastic anemia.

4 May 2026

Cellular aging in immune cells signals early onset of cognitive depression

Blood tests measuring the aging of certain white blood cells can predict cognitive and mood-related symptoms of depression, rather than physical symptoms.

4 May 2026

Food timing may shape how T cells respond to infection and therapy

Short-term nutritional state can reshape T cell metabolism, with post-meal lipid metabolism enhancing T cell metabolic capacity, cytokine production, and persistence after activation. The study identifies triglyceride-rich chylomicrons as key drivers of this effect, suggesting nutritional timing may matter for immune monitoring, vaccination research, and cell-therapy manufacturing.

30 Apr 2026

Gentler treatment improves survival in children with relapsed leukemia

A gentler treatment for children whose leukemia has come back could boost survival and quality of life, a study led by a UCL academic has found.

30 Apr 2026

Impaired protein recycling drives T cell exhaustion in cancer

T cells are crucial components of our immune system, serving as critical protectors against infection and disease.

30 Apr 2026

Extracellular vesicles from T cells enhance tumor immune response

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell Medicine.

30 Apr 2026

Study reveals new immune mechanism behind mevalonate kinase deficiency

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder.

30 Apr 2026

T1GRS model enhances prediction of genetic risk for Type 1 diabetes

In people with Type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy.

30 Apr 2026

Sickness behavior may be a coordinated whole organism immune strategy

Symptoms such as fatigue, loss of appetite, altered sleep, and social withdrawal are often treated as inconvenient side effects of infection.

30 Apr 2026

Degeneration in two brain regions causes severe narcolepsy symptoms

For nearly 25 years, scientists believed they knew what caused the most severe form of narcolepsy. A new UCLA Health study now suggests they were only half correct.

30 Apr 2026

How multi-omics is changing what scientists can see in the human immune system

Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation.

29 Apr 2026

Prehabilitation cuts surgery complications and hospital stays

Providing patients with structured exercise and nutrition support before surgery can reduce complications and shorten hospital stays, according to a new review published in the Journal of the American College of Surgeons (JACS).

29 Apr 2026

Maternal antibodies provide lifelong protection against adult gum disease

Mothers provide a hidden immune legacy that protects their children's teeth long after weaning is over. A new study reveals how maternal antibodies act as early life architects, programming the mouth to resist aggressive bacteria and prevent the bone loss associated with adult gum disease.

29 Apr 2026

Cryo-expansion microscopy reveals three-dimensional organization of killer T cells

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells.

29 Apr 2026

Eating creates temporary metabolic state that boosts T cell function

Diets and healthy eating habits hold promise for preventing and treating diseases, but far less is known about acute effects to the immune system shortly after a meal.

29 Apr 2026