Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Study reveals a chemical compound for the treatment of autoimmune diseases

Scientists in Japan have revealed a chemical compound that could be used for the treatment of various autoimmune diseases like multiple sclerosis and rheumatoid arthritis.

5 Mar 2023

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Scientists from Barts Cancer Institute at Queen Mary University of London and the Francis Crick Institute, have uncovered why patients with a rare type of blood cancer suffer from ineffective red blood cell production, and how vitamin B5 could be combined with existing drugs to improve outcomes.

1 Mar 2023

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

In a recent study posted to the Preprints with The Lancet SSRN* server, a team of researchers in China developed a machine learning-based diagnostic tool to detect tuberculosis and drug-resistant tuberculosis using nanoparticle-enhanced laser desorption/ionization mass spectrometry (NPELDI MS) to determine metabolic fingerprints from serum samples.

28 Feb 2023

Mass spectrometry-based identification of COVID-19 biomarkers

In a recent study published in the journal Metabolites, researchers reported that mass spectrometry (MS)-based metabolomic approaches have a high potential for biomarker discovery.

28 Feb 2023

Metabolomic differences in breast milk throughout lactation

Researchers characterize the cellular metabolome of breast milk throughout the course of lactation.

28 Feb 2023

Different cellular building blocks are not produced at the same time, research shows

Textbooks will tell you that in dividing cells, the production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level.

27 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments.

24 Feb 2023

Researchers successfully grow electrodes in living tissues

The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body's molecules as triggers.

24 Feb 2023

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

Researchers compare the pharmacokinetics and pharmacodynamics of oral Δ9-tetrahydrocannabinol-dominant and cannabidiol-dominant cannabis extracts that contained the same Δ9-THC dose (20 mg).

24 Feb 2023

Researchers map the DNA damage in human lung cells after BaP exposure

People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene (BaP), is known to damage DNA.

22 Feb 2023

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

In this interview, AZoM speaks to Rohan Thakur, the President of Life Science Mass Spectrometry at Bruker, about what the opportunities of the market are and how Bruker is planning on rising to the challenge.

From Bruker Daltonics 22 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

Cannabidiol could help curb the urge for smoking cigarettes

Cannabidiol or CBD, a non-psychoactive component of cannabis, inhibits the metabolism of nicotine, new research has found, meaning it could help tobacco users curb the urge for that next cigarette.

16 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Researchers assessed the different impacts of diet on the gut microbiome.

15 Feb 2023

Strip-type urine sensor can aid in cancer diagnosis

A research team led by Dr. Ho Sang Jung of the Surface & Nano Materials Divison of the Korea Institute of Materials Science (KIMS), a government-funded research institute under the Ministry of Science and ICT, conducted joint research with Professor Junsuk Rho of POSTECH and Professor Samjin Choi of Kyung Hee University Medical School to find metabolites in urine.

14 Feb 2023

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Researchers performed a multi-omics investigation of gut microbiome-host interactions and plasma metabolomics among myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) patients.

10 Feb 2023

Lifestyle-related metabolite biomarker may be a target to reduce stroke risk in Black adults

Researchers have identified a lifestyle-related metabolite biomarker called gluconic acid that is associated with high blood pressure, increased risk of ischemic stroke, eating a Southern diet, lower level of education and lack of exercise, among Black adults, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Metabolite News and Research

Further Reading

Study reveals a chemical compound for the treatment of autoimmune diseases

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

The rapid diagnosis of drug-resistant and drug-sensitive tuberculosis using mass spectrometry and machine learning

Mass spectrometry-based identification of COVID-19 biomarkers

Metabolomic differences in breast milk throughout lactation

Different cellular building blocks are not produced at the same time, research shows

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Difference between human and mouse lung tumor cells explains the discrepancy in cancer drug results

Researchers successfully grow electrodes in living tissues

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

Researchers map the DNA damage in human lung cells after BaP exposure

When cancer research turns to the immune system – the critical role of peptides and immunopeptidomics

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Gut dysbiosis and sepsis susceptibility among pregnant women

Cannabidiol could help curb the urge for smoking cigarettes

Smoking and vaping may put healthy young people at risk of severe COVID

How does previous diet impact the endocannabinoidome and microbiome response to a short-term Mediterranean diet intervention?

Strip-type urine sensor can aid in cancer diagnosis

Multi-omics approach uncovers gut microbiome-host interactions in myalgic encephalomyelitis/chronic fatigue syndrome patients

Lifestyle-related metabolite biomarker may be a target to reduce stroke risk in Black adults

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