Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available.

18 Nov 2025

First-of-its-kind provincial registry opens to build Ontario’s hereditary cancer database

The Ontario Hereditary Cancer Research Network's (OHCRN) participant portal is now open and Ontarians at risk of hereditary cancers are invited to register.

17 Nov 2025

T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus

A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV) is due to the response of T cells against the disease, rather than the production of antibodies.

17 Nov 2025

Polymer physics offers fresh perspectives on neurodegenerative diseases

Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key pathology in Alzheimer's disease, the formation of fibrils of tau proteins.

17 Nov 2025

Study highlights need for XDP specific diagnostic assays

Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects primarily men of Filipino ancestry.

17 Nov 2025

Johns Hopkins study links mild pancreatic duct dilatation to higher cancer risk

Pancreatic ductal adenocarcinoma is projected to become the second-leading cause of cancer death in the United States by 2030, according to the National Institutes of Health (NIH).

14 Nov 2025

Uncovering hidden causes of recurrent pregnancy loss with optical genome mapping

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues.

14 Nov 2025

Innovative test for Lyme disease offers hope for faster diagnosis

Researchers at Dartmouth Hitchcock Medical Center have developed a way to diagnose Lyme disease earlier and more accurately than traditional testing methods.

14 Nov 2025

New molecular test revolutionizes fungal infection diagnosis

Certain serious fungal infections occur in regions of the United States with specific environments and are often tied to soil exposure.

14 Nov 2025

Transforming precision oncology with medical imaging foundation models

Medical imaging foundation models are ushering in a new era for precision oncology. By integrating massive multimodal datasets and advanced AI algorithms, these models achieve unprecedented accuracy in early cancer screening, treatment planning, and prognosis prediction.

14 Nov 2025

Bruker announces advancements in immunopeptidomics, de novo PTM analysis, and proteoform profiling

international HUPO, Bruker Corporation today announced new machine learning additions to Bruker ProteoScape™ software for immunopeptidomics and PTM analysis.

From Bruker Daltonics 14 Nov 2025

Scientists map the genetic control system behind FOXP3 in immune cells

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

13 Nov 2025

New approach revives DNA from historic medical tissues

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

13 Nov 2025

Scientists discover hidden weakness in Lyme disease bacterium

For decades, Lyme disease has frustrated both physicians and patients alike. Caused by the corkscrew-shaped bacterium Borrelia burgdorferi, the infection, if left untreated, can linger for months, leading to fever, fatigue and painful inflammation.

13 Nov 2025

Research provides new insights into postoperative risk stratification for ampullary adenocarcinoma

Despite advances in cancer care, treatment strategies for ampullary adenocarcinoma (AAC) remain uncertain. Its anatomic location and biological diversity lead to variable clinical behavior and outcomes.

13 Nov 2025

Scientists develop innovative technique to locate microplastics

While microplastic pollution continues to advance, research into its possible effects on health remains hampered by technical hurdles: to date, there are no suitable methods for precisely identifying the particles in the body without destroying tissue.

13 Nov 2025

Stanford scientists discover unexpected cancer resistance in aged mice

Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led by Stanford University researchers.

12 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Common antibiotic can improve survival and neurological outcomes in CNS-TB

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated that doxycycline, a commonly available and inexpensive antibiotic, can improve survival rates and neurological outcomes in Central Nervous System Tuberculosis (CNS-TB) in a preclinical non-human study.

12 Nov 2025

Pathology News and Research

Further Reading

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

First-of-its-kind provincial registry opens to build Ontario’s hereditary cancer database

T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus

Polymer physics offers fresh perspectives on neurodegenerative diseases

Study highlights need for XDP specific diagnostic assays

Johns Hopkins study links mild pancreatic duct dilatation to higher cancer risk

Uncovering hidden causes of recurrent pregnancy loss with optical genome mapping

Innovative test for Lyme disease offers hope for faster diagnosis

New molecular test revolutionizes fungal infection diagnosis

Transforming precision oncology with medical imaging foundation models

Bruker announces advancements in immunopeptidomics, de novo PTM analysis, and proteoform profiling

Scientists map the genetic control system behind FOXP3 in immune cells

New approach revives DNA from historic medical tissues

Scientists discover hidden weakness in Lyme disease bacterium

Research provides new insights into postoperative risk stratification for ampullary adenocarcinoma

Scientists develop innovative technique to locate microplastics

Stanford scientists discover unexpected cancer resistance in aged mice

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Common antibiotic can improve survival and neurological outcomes in CNS-TB

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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