Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Alefacept drug shows encouraging results in phase 2 trial for type 1 diabetes

A drug formerly used to treat the skin disorder psoriasis has shown encouraging results in a phase 2 trial to assess its effectiveness in treating type 1 diabetes, according to new research published in The Lancet Diabetes & Endocrinology.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Rice University researchers come up with touch-to-access security for implanted devices

Pacemakers, insulin pumps, defibrillators and other implantable medical devices often have wireless capabilities that allow emergency workers to monitor patients. But these devices have a potential downside: They can be hacked.

24 Sep 2013

FDA's final guidance outlines tailored approach to mobile medical apps

Today, the U.S. Food and Drug Administration issued final guidance for developers of mobile medical applications, or apps, which are software programs that run on mobile communication devices and perform the same functions as traditional medical devices. The guidance outlines the FDA's tailored approach to mobile apps.

24 Sep 2013

Addition of walnuts to diet can protect against diabetes and heart disease in at-risk individuals

Medical researchers from the Yale-Griffin Prevention Research Center in Connecticut have found evidence suggestive that adding walnuts to one's diet can protect against diabetes and heart disease in at-risk individuals.

24 Sep 2013

Researchers report encouraging results from T1DAL study on type 1 diabetes

Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby MD, PhD from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with additional support from JDRF, are published today in The Lancet Diabetes & Endocrinology.

23 Sep 2013

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

The Cardiovascular Research Foundation (CRF) has announced the late breaking trials and first report investigations that will be presented at next month's Transcatheter Cardiovascular Therapeutics (TCT) 2013 scientific symposium.

21 Sep 2013

DiaRem score predicts diabetes remission after gastric bypass

A new scoring system offers a “scientifically valid” way of predicting the 5-year likelihood for diabetes remission in patients undergoing gastric bypass surgery, say the researchers who developed the score.

20 Sep 2013

New islet transplantation improves results for patients with type 1 diabetes

The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes, and may offer a more durable alternative to a whole pancreas transplant.

20 Sep 2013

New research explores effects of avocado consumption in healthy overweight adults

New research findings on avocado consumption, presented as two posters at the IUNS 20th International Congress of Nutrition, in Granada, Spain suggest that although calorie consumption at dinner was unchanged, inclusion or addition of fresh Hass Avocado to a meal may help to reduce hunger and the desire to eat in overweight adults.

19 Sep 2013

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Boehringer Ingelheim and Eli Lilly and Company today announced they will feature five oral and 12 poster presentations for linagliptin and the investigational compound empagliflozin* at the 49th Annual Meeting of the European Association for the Study of Diabetes (EASD) which will take place in Barcelona, from 23 – 27 September. The presentations will add to the already existing body of data on safety and efficacy of these two compounds.

18 Sep 2013

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum, which is able to sense cellular stress and trigger either rescue responses or the death of the cell.

18 Sep 2013

Scientists isolate, grow stem cells from the pancreases of mice

Scientists have succeeded in growing stem cells that have the ability to develop into two different types of cells that make up a healthy pancreas. The research team led by Dr. Hans Clevers of the Hubrecht Institute, The Netherlands, have isolated and grown stem cells from the pancreases of mice using a 3-D culture system previously developed by the scientists.

18 Sep 2013

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

17 Sep 2013

Researchers identify new link between meal times and daily changes in immune system

A new link between meal times and daily changes in the immune system has been identified by UC San Francisco researchers, and has led them to question assumptions about the roles of specific immune cells in infection and allergy.

17 Sep 2013

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Vanderbilt's Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D.

17 Sep 2013

Researchers identify biomarker that can predict diabetes risk

Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

17 Sep 2013

Drug used in patients for cancer treatment has beneficial effects on diabetes

A pair of studies by researchers at the Stanford University School of Medicine has identified a molecular pathway - a series of interaction among proteins - involved in the development of diabetes. Furthermore, they have found that a drug already approved for use in humans can regulate the pathway.

16 Sep 2013

Novel DiaRem scoring system can predict diabetes remission after gastric bypass surgery

US Scientists have developed a simple scoring system (DiaRem), based on four readily available preoperative patient characteristics, that can predict which candidates for gastric bypass surgery are likely to achieve diabetes remission within 5 years.

13 Sep 2013

Diabetes Mellitus Incidence Cohort Registry study reveals mixture of diabetes phenotypes

The DiMelli (Diabetes Mellitus Incidence Cohort Registry) study examines the frequency and characteristics of diabetes phenotypes in children and young adults below the age of 20. The study was commissioned to investigate the increasing incidence of diabetes mellitus, particularly in childhood and early adulthood. The project is funded by the German Center for Diabetes Research (DZD).

13 Sep 2013

Insulin News and Research

Further Reading

Alefacept drug shows encouraging results in phase 2 trial for type 1 diabetes

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Rice University researchers come up with touch-to-access security for implanted devices

FDA's final guidance outlines tailored approach to mobile medical apps

Addition of walnuts to diet can protect against diabetes and heart disease in at-risk individuals

Researchers report encouraging results from T1DAL study on type 1 diabetes

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

DiaRem score predicts diabetes remission after gastric bypass

New islet transplantation improves results for patients with type 1 diabetes

New research explores effects of avocado consumption in healthy overweight adults

Efficacy and safety data on linagliptin and investigational compound empagliflozin* in various diabetes subpopulations presented by Boehringer Ingelheim and Eli Lilly and Company

Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Scientists isolate, grow stem cells from the pancreases of mice

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

Researchers identify new link between meal times and daily changes in immune system

Vanderbilt examines ability of drug abatacept to prevent type 1 diabetes

Researchers identify biomarker that can predict diabetes risk

Drug used in patients for cancer treatment has beneficial effects on diabetes

Novel DiaRem scoring system can predict diabetes remission after gastric bypass surgery

Diabetes Mellitus Incidence Cohort Registry study reveals mixture of diabetes phenotypes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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