Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

FDA recalls Nova Max Blood Glucose Test Strips due to faulty readings

The U.S. Food and Drug Administration is working with Nova Diabetes Care to recall 21 lots of glucose test strips marketed under the brand names Nova Max Blood Glucose Test Strips and Nova Max Plus Glucose Meter Kits. Nova Diabetes Care announced a recall on July 26, 2013.

1 Aug 2013

Genetics could help women at risk of developing gestational diabetes

New Northwestern Medicine- research on the genetics of diabetes could one day help women know their risk for developing gestational diabetes before they become pregnant -- and lead to preventive measures to protect the health of offspring.

1 Aug 2013

Adocia, Lilly terminate collaboration agreement relating to fast-acting insulin analog

Adocia, a biotechnology company specializing in the development of ‘best-in-class’ medicines from already approved therapeutic proteins, announced today that it had agreed with Eli Lilly and Company not to continue further joint research under the licensing agreement signed in December 2011 relating to use of Adocia's BioChaperone(R) technology for the formulation of fast acting insulin analog formulated with the BioChaperone(R) technology. Consequently, the two companies have terminated the collaboration.

30 Jul 2013

Glucose intolerance, insulin resistance not associated with pathological features of AD

Glucose intolerance or insulin resistance do not appear to be associated with pathological features of Alzheimer disease (AD) or detection of the accumulation of the brain protein β-amyloid (Αβ), according to a report published by JAMA Neurology, a JAMA Network publication.

30 Jul 2013

FDA acknowledges receipt of NDA resubmission of dapagliflozin drug for treatment of type 2 diabetes

AstraZeneca (NYSE: AZN) and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of the New Drug Application (NDA) resubmission for investigational drug dapagliflozin for the treatment of adults with type 2 diabetes.

26 Jul 2013

Artificial pancreas for type 1 diabetes patients: an interview with John Pritchard, Cambridge Consultants

Essentially, what an artificial pancreas would be doing is taking the blood glucose results from a continuous monitor and taking the data that the patient puts in about the amount she/he is eating, and then adjusting the amount of insulin being delivered by the pump based on a mathematical formula that would be very personalized to that patient.

25 Jul 2013

FDA takes action to remove illegal diabetes products from market

The U.S. Food and Drug Administration is taking action to remove from the market illegal products, including some labeled as dietary supplements, that claim to mitigate, treat, cure or prevent diabetes and related complications.

24 Jul 2013

Potential breakthrough to help prevent diabetes

The resistance to insulin seen in type 2 diabetics is caused partly by the lack of a protein that has not previously been associated with diabetes. This breakthrough could potentially help to prevent diabetes.

23 Jul 2013

Study shows that eating more eggs is not associated with high serum cholesterol in adolescents

Although in the late 20th century it was maintained that eating more than two eggs a week could increase cholesterol, in recent years experts have begun to refute this myth. Now, a new study has found that eating more eggs is not associated with higher serum cholesterol in adolescents, regardless of how much physical activity they do.

19 Jul 2013

Study examines relationship between religious practices and obesity among Indian immigrants

Asian Indians are one of the fastest growing ethnic groups in the United States, and roughly half a million people of Indian ancestry live in California - more than any other state. Individuals from this group are strongly predisposed to obesity-related conditions such as diabetes and heart disease, due in large part to physical inactivity, diets low in fruit and vegetables, and insulin resistance.

19 Jul 2013

FDA grants orphan drug designation to ARMAGEN's AGT-182 for treatment of Hunter syndrome

ARMAGEN announced today that the U.S. Food and Drug Administration has granted orphan drug designation to its lead product AGT-182 for the treatment of mucopolysaccharidosis type II (also known as Hunter syndrome or MPS II).

19 Jul 2013

Researchers develop new drug delivery technique for diabetes treatment

Researchers have developed a drug delivery technique for diabetes treatment in which a sponge-like material surrounds an insulin core. The sponge expands and contracts in response to blood sugar levels to release insulin as needed. The technique could also be used for targeted drug delivery to cancer cells.

19 Jul 2013

One step closer to understanding how to control cancer cells without harming healthy ones

The nasty side effects of radiation and chemotherapy are well known: fatigue, hair loss and nausea, to name a few. Cancer treatment can seem as harsh as the disease because it can't differentiate healthy cells from cancerous cells, killing both.

17 Jul 2013

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Alize Pharma, a company specialized in the development of drugs for the treatment of metabolic diseases and rare diseases, announces today the launch of the first Phase I clinical trial for AZP-531, its unacylated ghrelin analog, in type 2 diabetes.

16 Jul 2013

‘Risking It’ campaign to raise awareness on coronary heart disease

A health expert from Sheffield Hallam University has become the face of a national campaign against heart disease after making significant improvements to his own lifestyle.

From Sheffield Hallam University 15 Jul 2013

Scientists successfully transplant insulin-producing cells from one species to another

In the first step toward animal-to-human transplants of insulin-producing cells for people with type 1 diabetes, Northwestern Medicine- scientists have successfully transplanted islets, the cells that produce insulin, from one species to another. And the islets survived without immunosuppressive drugs.

15 Jul 2013

Patients with early AD also have undiagnosed pre-diabetes, says Georgetown neurologist

When Georgetown University neurologist R. Scott Turner, MD, PhD, began enrolling people with mild to moderate Alzheimer's disease into a nationwide study last year, he expected to find only a handful of participants with undiagnosed glucose intolerance, as all the patients were already under a doctor's care and those with known diabetes were excluded.

15 Jul 2013

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

These scientists under the leadership of Martin Bilban from the Clinical Institute of Laboratory Medicine at the MedUni Vienna discovered a chain of molecular mechanisms, which is kick-started by the formation of glucocorticoids.

12 Jul 2013

Risk-factor screening of high-risk children may delay or prevent chronic health conditions later in life

Mexican American children are experiencing substantial burdens of obesity, pre-diabetes, and other health problems which historically would have been expected to develop much later in life. The findings of a new study by Texas Biomed scientists in San Antonio argue for early screening and intervention to delay or avoid chronic health problems as these children age.

12 Jul 2013

Insulin News and Research

Further Reading

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

FDA recalls Nova Max Blood Glucose Test Strips due to faulty readings

Genetics could help women at risk of developing gestational diabetes

Adocia, Lilly terminate collaboration agreement relating to fast-acting insulin analog

Glucose intolerance, insulin resistance not associated with pathological features of AD

FDA acknowledges receipt of NDA resubmission of dapagliflozin drug for treatment of type 2 diabetes

Artificial pancreas for type 1 diabetes patients: an interview with John Pritchard, Cambridge Consultants

FDA takes action to remove illegal diabetes products from market

Potential breakthrough to help prevent diabetes

Study shows that eating more eggs is not associated with high serum cholesterol in adolescents

Study examines relationship between religious practices and obesity among Indian immigrants

FDA grants orphan drug designation to ARMAGEN's AGT-182 for treatment of Hunter syndrome

Researchers develop new drug delivery technique for diabetes treatment

One step closer to understanding how to control cancer cells without harming healthy ones

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

‘Risking It’ campaign to raise awareness on coronary heart disease

Scientists successfully transplant insulin-producing cells from one species to another

Patients with early AD also have undiagnosed pre-diabetes, says Georgetown neurologist

Scientists discover chain of molecular mechanisms set in motion by glucocorticoids

Risk-factor screening of high-risk children may delay or prevent chronic health conditions later in life

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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