Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

The number and severity of lower limb amputations have decreased in US

There have been dramatic decreases in the number and severity of lower limb amputations over the past decade, according to a new study published in the July 2013 issue of Foot & Ankle International.

12 Jul 2013

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Six graduate students and one undergraduate were named as recipients of Genetics Society of America poster awards at the 19th International C. elegans Meeting, held June 26 on the campus of the University of California, Los Angeles.

12 Jul 2013

Researchers identify receptor mutation that blocked estrogen action in young woman

A receptor mutation that essentially blocks estrogen's action has been identified for the first time a female, researchers report.

12 Jul 2013

Study shows rates of brain loss caused by aging and AD are higher for women

The rates of regional brain loss and cognitive decline caused by aging and the early stages of Alzheimer's disease (AD) are higher for women and for people with a key genetic risk factor for AD, say researchers at the University of California, San Diego School of Medicine in a study published online July 4 in the American Journal of Neuroradiology.

10 Jul 2013

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

In the constant cross talk between our brain and our gut, two gut hormones are already known to tell the brain when we have had enough to eat. New research suggests that boosting levels of these hormones simultaneously may be an effective new weapon in the fight against obesity.

10 Jul 2013

Study shows female obesity may reduce receptivity of uterus to embryo implantation

An analysis of almost 10,000 first cycles of egg donation treatment at one of Europe's largest IVF centres shows that female obesity reduces the receptivity of the uterus to embryo implantation and thereby compromises reproductive outcome.

10 Jul 2013

Acorda Therapeutics acquires two neuropathic pain management assets from NeurogesX

Acorda Therapeutics, Inc. today announced that it has acquired two neuropathic pain management assets from NeurogesX, Inc. Qutenza is approved by the U.S. Food and Drug Administration for the management of neuropathic pain associated with postherpetic neuralgia.

9 Jul 2013

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Two drugs, telmisartan and valsartan, which are used to reduce blood pressure in people with diabetes, are associated with a lower risk of hospitalization for heart attack, stroke or heart failure, according to a study published in CMAJ (Canadian Medical Association Journal).

9 Jul 2013

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

Why do so many mothers have difficulty making enough milk to breastfeed? A new study by scientists at Cincinnati Children's Hospital Medical Center and the University of California Davis adds to their previous research implicating insulin's role in lactation success.

6 Jul 2013

State highlights: Calif. bill to fine firms with workers on Medi-Cal fails; Pa. eyes disallowing apologies used against doctors in court-proceedings

A California proposal to fine large companies that have workers on Medi-Cal came up short in an initial vote in the Assembly amid strong business opposition. The proposed fines could reach about $5,000 per full-time employee who receives Medi-Cal, the state Medicaid program for the poor. The bill, AB 880, garnered 46 votes in the 80-member chamber Thursday, short of the 54 votes, or two-thirds majority, needed. The measure could come up for reconsideration as early as next week (Terhune, 6/27).

2 Jul 2013

Researchers discover an important mechanism that regulates proteasome activity

Dysfunction of the ubiquitin-proteasome system (UPS) has been detected in many neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, and certain types of cancer. Such dysfunction is also believed to be related to some degenerative muscle diseases. Researchers at the University of Helsinki, Finland, have now discovered an important mechanism that regulates proteasome activity.

1 Jul 2013

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M), has found that patients receiving the transplants, when compared to a control group of TD2M patients who did not receive transplantation, required less insulin post-transplantation.

30 Jun 2013

People have differing abilities to release and react to insulin depending on ethnicity, says study

People have differing abilities to release and react to insulin depending on ethnicity, according to a new study from researchers at Lund University in Sweden, Stanford University and Kitasato University.

28 Jun 2013

New approaches to regenerate insulin-producing cells for type I diabetes

They have also shown that any pancreatic β cells can be regenerated several times and that chemically-induced diabetes in mice can thus be "treated" repeatedly. The challenge for the researchers is now to show that these procedures can be applied to humans.

28 Jun 2013

Research shows food contaminants are responsible for metabolic changes in obese mice

In order to get a better understanding of these effects, researchers from the Inserm cardiovascular, metabolism, diabetology and nutrition unit introduced a "cocktail" of contaminants mixed with low doses of dioxin, PCB, bisphenol A and phtalates into the feeding of mice that had already been rendered obese by a high-fat diet.

28 Jun 2013

Study shows "bioadhesive" coating can increase intestinal uptake of protein-based drugs

For protein-based drugs such as insulin to be taken orally rather than injected, bioengineers need to find a way to shuttle them safely through the stomach to the small intestine where they can be absorbed and distributed by the bloodstream.

28 Jun 2013

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find. A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta (Αβ) plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found.

28 Jun 2013

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Type 1 diabetes is an attack by the immune system of the islet of Langerhans within the pancreas. Basically, the islet of Langerhans harbor beta cells, which produce insulin and when the islets are attacked, the beta cells destruct and there is no more insulin. When the insulin level goes low, blood glucose levels go high and that creates a problem.

28 Jun 2013

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

Two UC Irvine research groups have received $2.27 million from the JDRF to develop innovative methods of treating and possibly curing Type 1 diabetes.

27 Jun 2013

A paradigm shift for treatment of muscular dystrophy

Researchers at Boston University College of Health & Rehabilitation Sciences: Sargent College have identified a combinatorial therapeutic approach that has proven effective in treating muscular dystrophy in a mouse model.

26 Jun 2013

Insulin News and Research

Further Reading

The number and severity of lower limb amputations have decreased in US

Seven named recipients of GSA poster awards at 19th International C. elegans Meeting

Researchers identify receptor mutation that blocked estrogen action in young woman

Study shows rates of brain loss caused by aging and AD are higher for women

Research: Boosting levels of gut hormones may be effective weapon in fight against obesity

Study shows female obesity may reduce receptivity of uterus to embryo implantation

Acorda Therapeutics acquires two neuropathic pain management assets from NeurogesX

Drugs used to control BP associated with lower risk of heart failure in diabetic patients

Study describes how human mammary gland becomes highly sensitive to insulin during lactation

State highlights: Calif. bill to fine firms with workers on Medi-Cal fails; Pa. eyes disallowing apologies used against doctors in court-proceedings

Researchers discover an important mechanism that regulates proteasome activity

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

People have differing abilities to release and react to insulin depending on ethnicity, says study

New approaches to regenerate insulin-producing cells for type I diabetes

Research shows food contaminants are responsible for metabolic changes in obese mice

Study shows "bioadhesive" coating can increase intestinal uptake of protein-based drugs

Study suggests amylin deposits are a new biomarker for age-related dementia and Alzheimer's

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

UCI researchers receive $2.27M to develop innovative methods of treating Type 1 diabetes.

A paradigm shift for treatment of muscular dystrophy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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