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Loyola announces plans to produce CAR-T cells for treating cancer

Loyola University Chicago and Loyola Medicine have announced plans to become the first Chicago center to produce cancer-fighting CAR-T cells to treat leukemia and lymphoma.

28 Sep 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

Obese mothers who underwent bariatric surgery can have safer deliveries

Obese mothers who lose weight through bariatric surgery can have safer deliveries. The positive effects are many, including fewer cesarean sections, infections, tears and hemorrhages, and fewer cases of post-term delivery or uterine inertia.

27 Sep 2018

UH pharmacologist receives NIH grant to improve kidney function in older people

Mohammad Asghar, associate professor of pharmacology at the University of Houston, has been awarded $459,000 from the National Institutes of Health/National Institute on Aging to improve kidney function in people 65 and older, a population at higher risk for developing impaired kidney function.

27 Sep 2018

Researchers to explore sex differences in cardiovascular and renal physiology

A person's sex can be a defining factor in how well--or how poorly--they respond to disease, therapy and recovery. Experts at the forefront of sex-specific research will convene next week at the sixth APS conference on sex differences in cardiovascular and renal physiology.

26 Sep 2018

Research reveals three-dimensional structure of membrane channel that controls blood pressure

New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure.

26 Sep 2018

Urine exRNA may be source of biomarkers for muscular dystrophy

Massachusetts General Hospital researchers have found that extracellular RNA in urine may be a source of biomarkers for the two most common forms of muscular dystrophy, noninvasively providing information about whether therapeutic drugs are having the desired effects on a molecular level.

26 Sep 2018

UCI study finds new cause of cerebral microbleeds

A team of researchers including UCI project scientist Rachita Sumbria, PhD and UCI neurologist Mark J. Fisher, MD have provided, for the first time, evidence that blood deposits in the brain may not require a blood vessel tear.

25 Sep 2018

Organs actively fighting back against autoimmune diseases, finds study

Organs affected by autoimmune disease could be fighting back by "exhausting" immune cells that cause damage using methods similar to those used by cancer cells to escape detection, according to a study by researchers at the University of Pittsburgh School of Medicine published today in the Journal of Clinical Investigation.

25 Sep 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

Obese pregnant women can restrict weight gain safely with proper nutrition guidance

Being obese or overweight during pregnancy can result in serious health problems for the mother and child. Obstetricians are often reluctant to recommend restricted weight gain for pregnant women due to safety concerns for the baby and lack of time and tools to safely guide women in their weight control efforts.

24 Sep 2018

Academics receive prestigious awards for achievements in blood pressure research

Two academics from Queen Mary University of London have received prestigious awards from the International Society of Hypertension 2018 in recognition of their achievements in blood pressure research.

24 Sep 2018

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Non-steroidal anti-inflammatory drugs, or NSAIDs, are commonly used as inflammation blockers worldwide. However, recent clinical data show these painkillers can have serious side effects that create some risk of heart attacks, strokes, and kidney or heart failure.

21 Sep 2018

Study reveals promising new drug candidate to treat acute renal failure

A protein produced by the human body appears to be a promising new drug candidate to treat conditions that lead to acute renal failure. This is shown by a study conducted at São Paulo State University in São José do Rio Preto, Brazil.

20 Sep 2018

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

Sesen Bio, Inc., a late-stage clinical company developing fusion protein therapies for the treatment of cancer, today announced that the company will present its three-month Phase 3 VISTA Trial data during a poster session at the Global Congress on Bladder Cancer 2018.

20 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

Young children's oral microbiota could serve as early indicator for obesity

Weight gain trajectories in early childhood are related to the composition of oral bacteria of two-year-old children, suggesting that this understudied aspect of a child's microbiota -- the collection of microorganisms, including beneficial bacteria, residing in the mouth -- could serve as an early indicator for childhood obesity.

19 Sep 2018

New study reveals mechanisms that lead to cognitive decline in Type 2 diabetes

Type 2 diabetes has been linked with an increased risk of cognitive dysfunction and dementia, but the underlying mechanisms are uncertain.

19 Sep 2018

NIH funds CWRU to investigate new imaging approach for diagnosing peripheral arterial disease

Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. More than 200 million people worldwide suffer from the condition.

18 Sep 2018

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.

18 Sep 2018

Kidney News and Research

Loyola announces plans to produce CAR-T cells for treating cancer

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Obese mothers who underwent bariatric surgery can have safer deliveries

UH pharmacologist receives NIH grant to improve kidney function in older people

Researchers to explore sex differences in cardiovascular and renal physiology

Research reveals three-dimensional structure of membrane channel that controls blood pressure

Urine exRNA may be source of biomarkers for muscular dystrophy

UCI study finds new cause of cerebral microbleeds

Organs actively fighting back against autoimmune diseases, finds study

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

Obese pregnant women can restrict weight gain safely with proper nutrition guidance

Academics receive prestigious awards for achievements in blood pressure research

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Study reveals promising new drug candidate to treat acute renal failure

Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Young children's oral microbiota could serve as early indicator for obesity

New study reveals mechanisms that lead to cognitive decline in Type 2 diabetes

NIH funds CWRU to investigate new imaging approach for diagnosing peripheral arterial disease

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

Free guide - Everything about renal proximal tubule cells eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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