Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

MannKind completes AFREZZA Phase 3 clinical study in patients with type 1 diabetes

MannKind Corporation today announced that all follow-up visits have been completed for the patients enrolled in Study 171, a Phase 3 clinical study of AFREZZA (insulin human [rDNA origin]) inhalation powder, an investigational, ultra rapid-acting mealtime insulin therapy, administered using MannKind's next-generation inhaler. MannKind expects to release data from this study later this summer.

1 Jun 2013

Calif.'s Supreme Court considers whether school workers who are not nurses can administer insulin shots to children

The justices appear cool to the idea that only licensed nurses should be able to give the shots, despite arguments by the state nurses association.

31 May 2013

Popular artificial sweetener can modify how the body handles sugar, find researchers

Researchers at Washington University School of Medicine in St. Louis have found that a popular artificial sweetener can modify how the body handles sugar.

30 May 2013

Restoring blood vessels may help cure type 1 diabetes, finds University of Missouri scientist

Millions of people with type 1 diabetes depend on daily insulin injections to survive. They would die without the shots because their immune system attacks the very insulin-producing cells it was designed to protect. Now, a University of Missouri scientist has discovered that this attack causes more damage than scientists realized.

30 May 2013

Adult stem cells combined with new drug could hold key to curing type 1 diabetes

29 May 2013

Patented nicotinamide riboside launched by Chromadex

ChromaDex Corporation, an innovative natural products company that provides proprietary, science-based solutions and ingredients to the dietary supplement, food & beverage, animal health, cosmetic and pharmaceutical industries, announced today the launch of NIAGEN, its novel, patented, branded nicotinamide riboside.

29 May 2013

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Scientists at UC Irvine reported this week that a synthetic compound ShK-186, originally derived from a sea anemone toxin, has been found to enhance metabolic activity and shows potential as a treatment for obesity and insulin resistance.

28 May 2013

Children with Type 2 diabetes are at high risk to develop heart, kidney and eye problems

The news about youth and diabetes keeps getting worse. The latest data from the national TODAY diabetes study shows that children who develop Type 2 diabetes are at high risk to develop heart, kidney and eye problems faster and at a higher rate than people who acquire Type 2 diabetes as adults.

26 May 2013

New evidence shows intensive insulin therapy does not provide substantial benefits

High blood glucose is associated with poor outcomes in hospitalized patients, and use of intensive insulin therapy (IIT) to control hyperglycemia is a common practice in hospitals. But the recent evidence does not show a consistent benefit and even shows harms associated with the use of IIT, according to the American College of Physicians' (ACP) Clinical Guidelines Committee in a new evidence-based paper published today online in the American Journal of Medical Quality.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

Obesity directly tied to several cancers

"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or on chemotherapy - worse by any measure." Karen Basen-Engquist, Ph.D., Director of MD Anderson's new Center for Energy Balance in Cancer Prevention and Survivorship and professor of Behavioral Science.

22 May 2013

Study provides comprehensive blueprint for understanding diabetes

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

22 May 2013

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Melbourne researchers have identified an immune protein that has the potential to stop or reverse the development of type 1 diabetes in its early stages, before insulin-producing cells have been destroyed.

21 May 2013

Research: Frequency of candy consumption is not associated with adverse health risks

At a time when the spotlight is focused on obesity more than ever, new research suggests that frequency of candy consumption is not associated with weight or certain adverse health risks.

21 May 2013

UIC researchers to study gender differences in how the heart uses and stores fat

Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat -- its main energy source -- and how changes in fat metabolism play a role in heart disease, under a new $2 million, 4-year grant from the National Heart, Lung and Blood Institute.

21 May 2013

Study shows treatment of sleep apnea in patients with prediabetes improves blood sugar levels

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in Philadelphia.

20 May 2013

Targeting glucagon action: A new frontier for regulating diabetes

For the first time, scientists at the Toronto General Research Institute showed that targeting glucagon action in the brain may be a new frontier for regulating diabetes.

20 May 2013

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

An exploration of electronic "screen time" and sleep on mood, memory and learning was given the top Addiction Science Award at the 2013 Intel International Science and Engineering Fair - the world's largest science competition for high school students.

20 May 2013

Newer class of diabetes medications may also improve cardiovascular health, researchers report

A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported in a new meta-analysis presented yesterday at the American Society of Hypertension's Annual Scientific Meeting and Exposition.

17 May 2013

FDA clears Oramed Pharmaceuticals' IND for ORMD-0801

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that the United States Food and Drug Administration has cleared the Company's Investigational New Drug application for ORMD-0801, its oral insulin capsule.

17 May 2013

Insulin News and Research

Further Reading

MannKind completes AFREZZA Phase 3 clinical study in patients with type 1 diabetes

Calif.'s Supreme Court considers whether school workers who are not nurses can administer insulin shots to children

Popular artificial sweetener can modify how the body handles sugar, find researchers

Restoring blood vessels may help cure type 1 diabetes, finds University of Missouri scientist

Adult stem cells combined with new drug could hold key to curing type 1 diabetes

Patented nicotinamide riboside launched by Chromadex

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Children with Type 2 diabetes are at high risk to develop heart, kidney and eye problems

New evidence shows intensive insulin therapy does not provide substantial benefits

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Obesity directly tied to several cancers

Study provides comprehensive blueprint for understanding diabetes

Newly discovered immune protein has potential to stop or reverse type 1 diabetes

Research: Frequency of candy consumption is not associated with adverse health risks

UIC researchers to study gender differences in how the heart uses and stores fat

Study shows treatment of sleep apnea in patients with prediabetes improves blood sugar levels

Targeting glucagon action: A new frontier for regulating diabetes

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

Newer class of diabetes medications may also improve cardiovascular health, researchers report

FDA clears Oramed Pharmaceuticals' IND for ORMD-0801

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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