Therapeutics News and Research

RSS

Research shows how a protein's small change leads to big trouble for cells

In molecular biology, chaperones are a class of proteins that help regulate how other proteins fold. Folding is an important step in the manufacturing process for proteins. When they don't fold the way they're supposed to, it can lead to the development of diseases such as cancer.

30 Jun 2020

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

30 Jun 2020

Newly identified molecules can help develop COVID-19 therapeutics

SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells.

30 Jun 2020

A glycan analysis of SARS-CoV-2 ACE2 complex

Researchers in the U.S. have produced molecular dynamic simulations of the Spike protein found on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its interaction with the host cell receptor angiotensin-converting enzyme 2 (ACE2).

29 Jun 2020

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

Scientists have new evidence that overactive neutrophils--a common type of circulating immune cell--may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19.

29 Jun 2020

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells.

29 Jun 2020

New rapid genomic testing can improve therapy selection for colorectal cancer patients

Genomic mutation testing is critical to therapeutic selection and management of patients with colorectal cancer. In a new multicenter study, researchers compared a new cartridge-based laboratory testing device called the Idylla automated system (Biocartis) to current standard-of-care testing methods.

26 Jun 2020

Chemically engineered peptides could help fight persistent human health challenges

Chemically engineered peptides, designed and developed by a team of researchers at Rensselaer Polytechnic Institute, could prove valuable in the battle against some of the most persistent human health challenges.

26 Jun 2020

Dotmatics acquires BioBright to innovate and drive lab data automation

Dotmatics Ltd., a scientific informatics software and services company that is driving the automation of laboratory data workflows for scientific discovery and innovation research, has today announced that it has entered into an agreement to acquire BioBright LLC, a leader in automating the flow of data from laboratory instruments to a secure cloud.

From Dotmatics 26 Jun 2020

Study shows why ApoE4 increases risk of Alzheimer's disease

Apolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients, including with polyunsaturated fatty acids - which are building blocks of the membranes surrounding the neurons.

26 Jun 2020

Researchers identify new molecules to study specific glial cells integral to synapses

While the brain is composed of two types of cells, glia tend to receive far less attention for their importance in brain function and disease than the more celebrated neurons.

26 Jun 2020

USask researchers receive $900,000 to help strengthen Canada's rapid response to COVID-19

The Canadian Institutes of Health Research has awarded three University of Saskatchewan research teams a total of $900,000 to help strengthen Canada's rapid response to the COVID-19 pandemic which had killed more than 450,000 people worldwide.

25 Jun 2020

Synthesis of bioactive natural compounds for the battle against cancer

Phytoalexins are bioactive phytochemicals that have attracted much attention in recent years due to their health-promoting effects in humans and their vital role in plant health.

25 Jun 2020

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

A seminal study by US researchers, currently available on the bioRxiv* preprint server, demonstrates how structure-based design can be efficiently employed to develop molecular probes targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike and its domains, with possible future use in diagnostics, treatment and vaccine development.

24 Jun 2020

Face masks can slow the spread of COVID-19

Regions with an early interest in face masks had milder COVID-19 epidemics, according to a new letter-to-the-editor published in the American Journal of Respiratory and Critical Care Medicine.

24 Jun 2020

New dengue virus serotype DENV3 has re-emerged in Singapore after three decades

Dengue infections are rising, even as public health authorities are battling to contain the spread of the coronavirus. Dengue virus serotype 2 (DENV2) had previously been the predominant serotype but DENV3 has re-emerged in Singapore after almost three decades.

23 Jun 2020

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies

23 Jun 2020

Study identifies new gene variants tied to type-2 diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration's Corporal Michael J. Crescenz Veterans Affairs Medical Center found hundreds of genetic variants never before linked to the disease.

23 Jun 2020

ILC Therapeutics announces research partnership with University of St Andrews to fight against COVID-19

UK-based biotechnology firm ILC Therapeutics has announced a research partnership with the University of St Andrews in a bid to progress a therapeutic drug which can treat COVID-19 towards clinical trials.

23 Jun 2020

Jubilant Therapeutics announces preclinical data of dual LSD1 and HDAC6 inhibitor at AACR 2020

Jubilant Therapeutics Inc., a biopharmaceutical company advancing small molecule modulators to address unmet medical needs in oncology and autoimmune diseases, today announced that preclinical data of dual LSD1 and HDAC6 inhibitor JBI-802, will be presented in a poster session at the American Association for Cancer Research 2020 Virtual Annual Meeting II.

23 Jun 2020

Therapeutics News and Research

Research shows how a protein's small change leads to big trouble for cells

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Newly identified molecules can help develop COVID-19 therapeutics

A glycan analysis of SARS-CoV-2 ACE2 complex

Overactive neutrophils may drive life-threatening blood clots in some COVID-19 patients

Clinically approved drugs could disrupt SARS-CoV-2 from hijacking cells

New rapid genomic testing can improve therapy selection for colorectal cancer patients

Chemically engineered peptides could help fight persistent human health challenges

Dotmatics acquires BioBright to innovate and drive lab data automation

Study shows why ApoE4 increases risk of Alzheimer's disease

Researchers identify new molecules to study specific glial cells integral to synapses

USask researchers receive $900,000 to help strengthen Canada's rapid response to COVID-19

Synthesis of bioactive natural compounds for the battle against cancer

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

Face masks can slow the spread of COVID-19

New dengue virus serotype DENV3 has re-emerged in Singapore after three decades

UK announces research partnership with Atomwise to explore potential COVID-19 therapies

Study identifies new gene variants tied to type-2 diabetes

ILC Therapeutics announces research partnership with University of St Andrews to fight against COVID-19

Jubilant Therapeutics announces preclinical data of dual LSD1 and HDAC6 inhibitor at AACR 2020

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News