Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Walking speed before hip replacement predicts long-term recovery success

Total hip arthroplasty (hip replacement) is a common treatment for hip osteoarthritis, a degenerative joint disease caused by cartilage in the hip joint wearing down.

1 Dec 2025

Study finds surprising differences in knee injuries between men and women

One of the largest MRI-based studies comparing knee injuries between men and women reveals surprising differences in injury patterns based on gender and age.

1 Dec 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

Breakthrough in bone regeneration using nanoparticle-stem cell hybrid

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

12 Nov 2025

Football injuries, not injections, explain why retired players face higher osteoarthritis risk

Retired UK male footballers face a markedly higher risk of foot and ankle osteoarthritis (OA), primarily due to prior injuries sustained during their careers. While corticosteroid injections were linked with OA, this association likely reflects treatment for injury rather than a direct cause.

23 Oct 2025

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

A new paper in Rheumatology, published by Oxford University Press, finds that retired UK male professional football players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement.

22 Oct 2025

Aerobic exercise found to be most effective for knee osteoarthritis

For patients with knee osteoarthritis, aerobic activities such as walking, cycling, or swimming are likely to be the best exercise for improving pain, function, gait performance, and quality of life, finds a study published by The BMJ today.

15 Oct 2025

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.

29 Sep 2025

Artificial intelligence transforms lumbar spine modeling for faster patient care

Nearly 3 in 10 adults in the United States have experienced lower back pain in any three-month period, making it the most common musculoskeletal pain.

17 Sep 2025

Smart material delivers drugs in response to arthritis flare-ups

Researchers have developed a material that can sense tiny changes within the body, such as during an arthritis flare-up, and release drugs exactly where and when they are needed.

8 Sep 2025

Gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

1 Sep 2025

Insights into the clinical presentation and management of sellar chondrosarcomas

Chondrosarcomas are a malignant form of bone cancer that is composed of cartilage-forming tumor cells. Sellar chondrosarcomas, which occur in the sellar region at the base of the skull, are a very rare manifestation of chondrosarcoma, making up only around 0.2% of all tumors found in the skull.

22 Aug 2025

Investigation raises concerns over tooth stem cell banking claims

Parents are spending thousands of pounds to bank stem cells from their children's milk teeth – but the recipient companies' claims about their future medical value are unproven and potentially misleading, reveals an investigation by The BMJ, published today.

21 Aug 2025

Patient's own cartilage cells from surgery offer hope for hip repair

Researchers at the University of Missouri are on a mission to help patients recover from hip surgery with less pain, and they may have found an innovative solution: using the patient's own cartilage cells.

19 Aug 2025

Electromechanical reshaping could be a gentler alternative to LASIK

Millions of Americans have altered vision, ranging from blurriness to blindness. But not everyone wants to wear prescription glasses or contact lenses.

18 Aug 2025

Researchers capture first 3D real-time images of human embryo implantation

Researchers at the Institute for Bioengineering of Catalonia (IBEC) in collaboration with the Dexeus University Hospital have captured unparalleled images of a human embryo implanting.

18 Aug 2025

Scaffold-free cellular spheroids generate integrated osteochondral grafts

A new study in the peer-reviewed journal Tissue Engineering, Part A demonstrates the potential to produce cellular spheroids, from a clinically relevant embryonic stem cell derived mesenchymal stem cell (ES-MSC) source, to generate scaffold-free chondrogenic or osteochondrogenic graft tissues.

14 Aug 2025

New research explores foot positioning to treat knee osteoarthritis

Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an uncurable disease in which the cartilage cushion inside a joint breaks down.

13 Aug 2025