Crohn’s Disease News and Research

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Sulfide-producing bacteria may explain lingering symptoms in Crohn's disease

A study from University of Michigan researchers may provide an explanation for why some patients with Crohn's disease continue to experience symptoms, even in the absence of inflammation.

19 Dec 2024

Mediterranean diet linked to reduced risk of inflammatory bowel disease

Research suggests the Mediterranean diet supports inflammatory bowel disease management, enhancing gut microbiota with nutrients like omega-3 fatty acids.

10 Dec 2024

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

Women with premature ovarian insufficiency face higher risk of autoimmune diseases

Research reveals a significant association between premature ovarian insufficiency and autoimmune diseases, highlighting hypothyroidism as a common condition.

2 Dec 2024

Western diet accelerates endometriosis growth and disrupts gut health

This study found that a Western diet doubles the growth of endometriotic lesions in mice and depletes the gut microbiome's beneficial bacterium, Akkermansia muciniphila, which may exacerbate endometriosis symptoms.

12 Nov 2024

Progress in early detection and screening methods for pancreatic cancer

The evolution of pancreatic cancer screening technologies is pivotal for early detection, addressing key challenges to enhance survival rates and patient care.

11 Nov 2024

New insights on the association between genes, gut microbiota, and mental health

The study identifies links between gut microbiota, genetic variants in IBD, and mental health disorders, offering insights into potential biomarkers for CMDs.

31 Oct 2024

How carnitine transporters boost reproductive health

Research uncovers the critical role of carnitine transporters in maintaining fertility by regulating energy metabolism and protecting reproductive cells from oxidative stress. It suggests new pathways for treating infertility through carnitine supplementation and targeted therapies.

6 Oct 2024

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Study reveals significant gut microbial differences across diseases in the Chinese population, identifying universal microbial signatures that could predict disease states with high accuracy.

2 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease - an autoimmune disorder - is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

Researchers compare the therapeutic efficacy of risakizumab and ustekinumab for the treatment of moderate-to-severe Crohn’s disease.

23 Aug 2024

APOE ε4 carrier status increases the long-term cognitive decline risk associated with herpes zoster

The long-term subjective cognitive decline risk associated with Herpes zoster infections.

19 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.

6 Aug 2024

New research may help explain recurrent Crohn's disease in children

Remarkable new research by a University of Virginia undergraduate may help explain recurrent Crohn's disease in children and open the door to new ways to treat or even cure the devastating condition.

28 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

The role of banana lectin in mitigating inflammatory bowel disease

The therapeutic role of recombinant banana lectin (rBanLec) concerning IBD control and raising vaccination rates.

3 Jun 2024

Podcast: New online tool helps young people better manage Crohn's disease

Aston University's Dr Cassie Screti joined the latest Aston Originals Health Matters podcast recorded for World Inflammatory Bowel Disease Day to discuss a new online tool to help young people better manage Crohn's disease, a type of inflammatory bowel disease (IBD).

17 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024