Disease Modeling News and Research

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Innovative technique converts fibroblasts into functional cardiomyocytes

Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year.

24 Dec 2024

Global analysis highlights antibiotic consumption trends and AMR threat

A new study highlights recent, but fluctuating, growth in global human antibiotic consumption, one of the main drivers of growing antimicrobial resistance (AMR).

19 Nov 2024

Space-grown stem cells show promise for accelerating biotherapies

Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease, two Mayo Clinic researchers say.

4 Nov 2024

Human midbrain organoids: A promising tool in the fight against Parkinson's disease

Advancements in organoid technology are crucial for Parkinson's disease research, providing human-relevant models for studying disease and testing therapies.

23 Oct 2024

Transformative tissue engineering research in space

An "out-of-this-world" project has the potential to transform the future of tissue engineering and liver transplantation through innovative research conducted aboard the International Space Station (ISS).

18 Oct 2024

Tissue chips help translate respiratory disease research into clinical applications

Scientists are developing advanced tools to understand and treat neurological symptoms such as brain fog associated with respiratory diseases like influenza.

17 Oct 2024

Researchers uncover distinct cell vulnerabilities in Alzheimer’s progression with novel multiomics approach

Researchers used single-cell and spatial genomics to map cell-type-specific changes in the middle temporal gyrus, identifying distinct disease phases in Alzheimer’s progression.

16 Oct 2024

New imaging technology enhances real-time observation of living organoids

Organoids, which are 3D miniature organs that mimic the structure and function of human organs, play an essential role in disease research and drug development.

15 Oct 2024

Patient-derived gut organoids reveal new insights into Crohn's disease subtypes

Crohn's disease - an autoimmune disorder - is characterized by chronic inflammation of the digestive tract, resulting in a slew of debilitating gastrointestinal symptoms that vary from patient to patient.

26 Sep 2024

Centenarians' stem cells unlock secrets to healthy aging

Individuals who display exceptional longevity provide evidence that humans can live longer, healthier lives.

25 Sep 2024

New kidney chip offers breakthrough for drug development and personalized medicine

Developing advanced drug screening tools is crucial for the advancement of personalized medicine and the creation of more effective treatments. One organ receiving particular attention in this area is the kidney.

19 Sep 2024

Stem cell study identifies unique glial contributions to multiple sclerosis

A team of scientists from The New York Stem Cell Foundation (NYSCF) Research Institute and Case Western Reserve University has created the largest reported collection of stem cell models from multiple sclerosis (MS) patients and used them to identify unique ways in which glia – integral support cells in the brain – contribute to the disease.

26 Aug 2024

Study reveals how brain pathways aid motor recovery after injury

Stroke and spinal cord injuries can severely impair motor functions, and understanding how to promote recovery is a critical challenge.

23 Aug 2024

New treatment boosts pluripotent stem cell production in mice

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.

7 Aug 2024

Salk Institute receives CIRM funding for stem cell research on aging and neurodegeneration

The Salk Institute was awarded $3.6 million by the California Institute for Regenerative Medicine (CIRM), one of the world's largest institutions dedicated to regenerative medicine.

31 Jul 2024

2024 is shaping up to be “the year of iPSCs"

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From Axol Bioscience Ltd 31 Jul 2024

Breakthrough humanized mouse model offers new insights for immunotherapy development

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.

5 Jul 2024

New electrospinning innovations transform wearable and implantable medical devices

In a groundbreaking advancement that could reshape the landscape of precise medicine, researchers from the Beijing Institute of Technology and Rutgers University have unveiled a series of innovative electrospinning techniques capable of significantly enhancing the functionality and effectiveness of medical devices. This pioneering study, recently published in the Cyborg Bionic Systems journal, promises to revolutionize the creation and implementation of nano/microrobots, wearable/implantable biosensors, and organ-on-chip systems.

27 Jun 2024

New MOBE technology revolutionizes multiplexed genome editing

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

21 May 2024

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO).