Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

Raman spectroscopy enhances surgical precision for pediatric epilepsy treatment

More than 50 million people worldwide live with epilepsy, with approximately half of them being children. For about one-third of these patients, medications do not control their seizures, leaving surgery as the only viable option for seizure relief.

11 Mar 2025

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

11 Mar 2025

Feeding strategies in preterm infants do not alter brain growth or cognition

Early nutrition in very preterm infants does not significantly impact brain growth or neurodevelopment when following standardized clinical guidelines, despite initial unadjusted associations.

5 Mar 2025

Surprising study reveals dads’ weight and diet don’t impact baby’s size

A study shows paternal health factors like BMI and diet do not influence birth weight or length, emphasizing maternal diet's critical role in pregnancy.

4 Mar 2025

European project aims to develop new treatments for rare eye diseases

The Ocular Neurobiology laboratory at the Institute for Neurosciences, a joint center of Miguel Hernández University (UMH) in Elche and the Spanish National Research Council (CSIC), is participating in the European project RESTORE VISION, an ambitious initiative aimed at developing new treatments for rare eye diseases such as aniridia and neurotrophic keratopathy.

28 Feb 2025

Advancements in molecular diagnostics for hematopoietic and lymphocytic neoplasms

Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from manageable conditions to fatal diseases.

27 Feb 2025

Scientists aim to regenerate lungs for premature infants with BPD

Understanding resilience - the ability of injured lung tissue to heal and regenerate - may be key to advancing the treatment and prevention of life-threatening lung disease that occurs in extremely premature babies, a new study suggests.

25 Feb 2025

AI-powered tool improves the detection of focal cortical dysplasia

Scientists have developed an AI-powered tool that detects 64% of brain abnormalities linked to epilepsy that human radiologists miss.

24 Feb 2025

New study reveals LRP1's crucial role in bone formation and joint development

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development.

19 Feb 2025

HPV16 vaccine shows promise in treating precancerous cervical lesions

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

24 Jan 2025

New insights into respiratory syncytial virus and prevention strategies

Respiratory syncytial virus (RSV) is a major cause of respiratory infections, particularly in infants, children under 5 years, and older adults. Its rapid spread makes RSV a serious public health concern. Currently, there are no effective medications for RSV, and current treatment focuses on providing supportive care and preventing its spread.

20 Dec 2024

Using impulse oscillometry for lung function testing in preterm children

Infants born preterm remain vulnerable to numerous health complications, such as respiratory distress syndrome, chronic lung disease, and pulmonary dysfunction.

19 Dec 2024

Daily tablet shows promise in treating achondroplasia in children

A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study.

18 Nov 2024

Traditional and cutting-edge endoscopic modalities in colorectal cancer diagnosis

The evolution of gastrointestinal (GI) endoscopy has transformed CRC diagnostics since its early 20th-century origins.

8 Nov 2024

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to five percent of the adult population and can lead to high blood pressure, heart attack, or stroke.

14 Sep 2024

ANNs can identify lung disease in preterm infants by analyzing sleep breathing patterns

Artificial Neural Networks (ANNs) can be trained to detect lung disease in premature babies by analyzing their breathing patterns while they sleep, according to research presented at the European Respiratory Society (ERS) Congress in Vienna, Austria.

9 Sep 2024

Defective ZNRF3 gene causes opposing brain sizes and potential tumor risk

A gene called ZNRF3, known to be involved in cancer, also messes with the mind. The human brain relies on two copies of this gene to build a right-sized brain. If one of the copies is defective, the brain will be either too small or too large - known as mirror effect -, leading to various neurological symptoms.

23 Aug 2024

Expanding the TTN mutation spectrum for dilated cardiomyopathy diagnosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Dilated cardiomyopathy (DCM), a severe heart disease, is the leading cause of heart failure and sudden cardiac death worldwide.

19 Aug 2024

Increased skin-to-skin time linked to better neurodevelopment

Skin-to-skin cuddling with a parent has lasting cognitive benefits for premature babies, according to a new Stanford Medicine study. Preemies who received more skin-to-skin contact, also known as kangaroo care, while hospitalized as newborns were less likely to be developmentally delayed at 1 year of age, the study found.

8 Aug 2024

Novel blood test could predict chronic lung disease in preterm babies within hours of birth

A blood test can help predict which preterm babies will go onto develop chronic lung disease, allowing for earlier diagnosis and more targeted treatments, according to a new study.

7 Aug 2024