Green Fluorescent Protein (GFP) News and Research

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What is the potential role of sphingosine kinase inhibitors as antiviral agents?

In a new study, researchers explored sphingosine kinases inhibitors and characterized the role of SKs in Ebola virus (EBOV) entry.

16 Aug 2022

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

In a new study, researchers developed nanocomposite coatings to prevent surface contamination by a human coronavirus (HCoV).

4 Aug 2022

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

A recent study published in the Journal of Food Biochemistry discovered that peimine from Fritillaria might be a possible SARS-CoV-2 variant infection inhibitor.

2 Aug 2022

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

The study findings showed that the rapid antigen tests with the DMS approach could accurately identify antibody escape mutations in the SARS-CoV-2 N protein.

24 May 2022

Comparison of COVID-19 vaccination schemes

Researchers assessed SARS-CoV-2 neutralizing antibodies in Chile.

9 May 2022

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

In a recent study published in the journal Cell, researchers investigated distinguishing virological characteristics of Omicron sub-variant BA.2.

3 May 2022

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Researchers evaluated the importance of the P681 residue within the furin cleavage site of SARS-CoV-2 spike protein in determining the fusogenicity and syncytia formation ability of SARS-CoV-2 strains.

2 May 2022

Green tea catechin as pan-coronavirus attachment inhibitor

In a recent study posted to the Research Square* preprint server, researchers assessed the impact of green tea catechin epigallocatechin gallate (EGCG) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

27 Apr 2022

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

Researchers assessed the binding pocket of linoleic acid, an essential free-fatty acid in the receptor-binding domains of the spike protein of beta-coronaviruses.

26 Apr 2022

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Researchers investigated variations in the host immune response-elicited by non-structural protein 1 of coronaviruses.

22 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Researchers identified mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleoproteins (NP) epitope flanking regions and their potential effects on CD8+ T cell activation.

12 Apr 2022

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

A new study demonstrated that vascular inflammation leads to heightened SARS-CoV-2 infection in perivascular cells.

8 Apr 2022

SARS-CoV-2 spike S375F mutation triggered the explosive spread of Omicron

In a recent study posted to the bioRxiv* preprint server, researchers investigated the mutation in the viral spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 variant (referred to as Omicron in the present study) that is responsible for the variant’s virological features.

7 Apr 2022

Green Fluorescent Protein (GFP) News and Research

What is the potential role of sphingosine kinase inhibitors as antiviral agents?

Polymer-embedded copper-based nanoparticles prevent surface contamination by viruses

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

The impact of SARS-CoV-2 nucleocapsid protein mutations on the performance of rapid antigen tests

Comparison of COVID-19 vaccination schemes

SARS-CoV-2 BA.2 poses greater risk to global health than BA.1

P681 mutations in SARS-CoV-2 spike protein determine fusogenicity

Green tea catechin as pan-coronavirus attachment inhibitor

Free fatty acid-binding pocket found to be preserved across spike proteins of beta coronaviruses

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

SARS-CoV-2 mutations change proteasome processing to alter CD8+ T cell responses

Substantial SARS-CoV-2 infection in perivascular cells of inflamed blood vessels

SARS-CoV-2 spike S375F mutation triggered the explosive spread of Omicron

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Minimal system for SARS-CoV-2 based virus-like particle production to study viral assembly and entry

Glycogen synthase kinase-3 inhibitors found to attenuate COVID-19-associated cytokine storm

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

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