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Curcumin activates SIRT3 to protect bone structure in diabetic mice

In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.

13 Aug 2025

Polyphenols and exercise show promise in fighting gliomas

A new review in Food Science & Nutrition highlights how combining dietary polyphenols with structured exercise can enhance brain function, regulate epigenetics, and support glioma management. The authors outline mechanisms, patient-centered strategies, and research gaps for turning this synergy into clinical practice.

12 Aug 2025

AI model advances prediction of microsatellite status in cancer

One in every three people is expected to have cancer in their lifetime, making it a major health concern for mankind.

5 Aug 2025

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Researchers identified a combination of two existing cancer drugs, letrozole and irinotecan, that reversed Alzheimer’s disease-related changes in brain cell networks and improved memory in mouse models. The study supports a multi-cell-type, network-correcting strategy as a promising path for future Alzheimer’s treatments.

22 Jul 2025

Allergies linked to lower lung cancer risk, new study finds

A meta-analysis of nearly 3.9 million participants shows people with allergies have significantly lower odds of developing lung cancer. Allergic rhinitis is particularly protective, while eczema’s effect appears limited to men.

20 Jul 2025

Nigerian botanicals restore hormonal balance and fight menstrual pain in preclinical study

Researchers tested five Nigerian medicinal plants in female rats and found that these botanicals reversed MSG-induced hormonal imbalance, oxidative stress, and lipid disruptions linked to dysmenorrhea. The findings support further investigation of plant-based therapies for menstrual pain and related metabolic risks.

20 Jul 2025

Caloric restriction may help delay decline in reproductive function associated with aging

A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 20, 2025, titled "Short-term moderate caloric restriction in the rhesus macaque attenuates markers of ovarian aging in select populations."

24 Jun 2025

How Fluidics is Powering Modern Healthcare and Medical Device Innovation

The future of fluidics in healthcare: Blake Webb shares trends in automation and microfluidics that are reshaping medical diagnostics and laboratory processes.

From Fluid Metering, Inc. 12 Jun 2025

Eliminating stellate cells reduces liver metastasis in mouse models

The prestigious journal Hepatology Communications reports on the discovery by the Cancer and Translational Medicine research group of the University of the Basque Country (EHU).

10 Jun 2025

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

The SWOG S2302 Pragmatica-Lung trial, which broke new ground with its streamlined pragmatic design, unusually broad eligibility criteria, and reduced data collection, has quickly answered its primary question, finding that the investigational combination it tested did not significantly extend overall survival compared to standard of care treatments.

4 Jun 2025

Wilms tumor found to contain millions of genetic changes

Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children's tumours and possibly opening up new or repurposed treatment options.

29 May 2025

New brain imaging method shows promise for early diagnosis of Parkinson's disease

An international team, led by researchers at the Champalimaud Foundation (CF), has shown – for the first time in a realistic way – that it may be possible to diagnose Parkinson's disease (PD) years before it becomes untreatable, by scanning people's brains with functional magnetic resonance imaging (fMRI).

8 May 2025

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal meaningful weight loss and improved cardiometabolic markers, with a favorable safety profile.

4 May 2025

Manipulating a master regulator prevents tumor growth in mice

A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system's response to cancer.

24 Apr 2025

N-acetylcysteine protects against acyclovir-induced nephrotoxicity

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity.

18 Apr 2025

Some lung cancer patients maintain long-term control after stopping immunotherapy

A subset of patients with non-small cell lung cancer (NSCLC) who discontinued immune checkpoint inhibitor (ICI) therapy due to immune-related adverse events (irAEs) continued to experience long-term disease control.

18 Apr 2025

FOXR2 activation found in multiple pediatric brain tumor types

Physicians classify brain tumors and determine treatment options, in part, by the genes they express. According to World Health Organization standards, the abnormal activation of oncogene FOXR2 only occurs in central nervous system (CNS) neuroblastoma, but that may not be true.

16 Apr 2025

Histology News and Research

Curcumin activates SIRT3 to protect bone structure in diabetic mice

Polyphenols and exercise show promise in fighting gliomas

AI model advances prediction of microsatellite status in cancer

Dual cancer drugs restore memory and rewire brain cells in Alzheimer’s mouse models

Allergies linked to lower lung cancer risk, new study finds

Nigerian botanicals restore hormonal balance and fight menstrual pain in preclinical study

Caloric restriction may help delay decline in reproductive function associated with aging

How Fluidics is Powering Modern Healthcare and Medical Device Innovation

Eliminating stellate cells reduces liver metastasis in mouse models

SWOG S2302 Pragmatica-Lung study demonstrates value of streamlined clinical trials in real world settings

Wilms tumor found to contain millions of genetic changes

New brain imaging method shows promise for early diagnosis of Parkinson's disease

Semaglutide clears liver inflammation and cuts fibrosis in MASH patients, trial shows

Manipulating a master regulator prevents tumor growth in mice

N-acetylcysteine protects against acyclovir-induced nephrotoxicity

Some lung cancer patients maintain long-term control after stopping immunotherapy

FOXR2 activation found in multiple pediatric brain tumor types

Understanding the complex spectrum of Castleman disease

Human dental stem cells can be transformed into excitable neuronal cells, study shows

Cancer recurrence linked to residual disease missed by imaging

Life Science Microscopy eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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