Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Breast and prostate cancer survival worsens with metabolic syndrome

A SEER-Medicare analysis of more than 200,000 adults aged 66 and older found that metabolic syndrome was associated with about twice the adjusted hazard of death from any cause after breast or prostate cancer. The condition was also linked to higher cancer-specific, cardiovascular-specific, and liver-failure-specific mortality, although the observational design prevents causal conclusions.

14 Jul 2026

Cultural engagement linked to slower physiological aging in older adults

Higher levels of cultural engagement are significantly associated with lower physiological aging, suggests an analysis published online in the Journal of Epidemiology and Community Health.

14 Jul 2026

Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome

Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes in metabolic syndrome (MetS).

14 Jul 2026

Yogurt, prebiotics, and probiotics link to lower colorectal cancer odds in U.S. adults

A national NHANES analysis of 9,405 U.S. adults aged 50 and older found that any yogurt, prebiotic, or probiotic consumption was associated with about 50% lower odds of self-reported colorectal cancer. Because the study was cross-sectional, it cannot prove causation but supports further research into microbiota-targeted dietary strategies.

8 Jul 2026

Updated ABCs framework gives clinicians a clearer path to prevent heart disease

A 2026 State-of-the-Art review updates the ABCs of cardiovascular disease prevention to help clinicians apply contemporary risk assessment, lifestyle, pharmacologic, and cardiometabolic strategies in routine care. The framework emphasizes PREVENT™ risk equations, Life’s Essential 8, CKM syndrome, obesity care, lipid lowering, blood pressure control, healthy aging, heart failure prevention, and atrial fibrillation management.

7 Jul 2026

Thirty years of data reveal changing heart health trends in obesity

A study reveals narrowing gaps in blood pressure and cholesterol between obesity and normal BMI, highlighting evolving cardiometabolic risks over three decades.

6 Jul 2026

Plant-based diets offer heart benefits but may require supplements

A study reveals unsupplemented vegan diets in Northeast China lead to micronutrient deficiencies, despite benefits for body composition and cholesterol levels.

2 Jul 2026

Blood pressure and cholesterol gaps shrink among older adults with obesity

Over the last three decades, differences in unhealthy cholesterol levels and blood pressure between older adults with obesity and those with a normal Body Mass Index (BMI) have narrowed or disappeared in several high-income countries, suggests a study published in The Lancet.

1 Jul 2026

Experts reframe steatotic liver disease as a dynamic continuum

The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof. Tacke from Charité - Universitätsmedizin Berlin argue that metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol-associated liver disease (MetALD), and alcohol-associated liver disease (ALD) should not be regarded as rigid diagnostic categories, but rather as interconnected and evolving disease trajectories.

30 Jun 2026

UTSA researchers develop bait pellets to combat Lyme disease

A breakthrough in the fight against Lyme disease is moving from the laboratory to the hardware store.

30 Jun 2026

Okra supplements may lower cholesterol and inflammation markers in diabetes

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29 Jun 2026

Gene linked to lower BMI points researchers toward a new obesity target

A review in Cardiology in Review highlights GPR75, a receptor for 20-HETE, as a promising therapeutic target for obesity and metabolic syndrome. Evidence from genetic studies, cell experiments, and mouse models suggests that blocking this pathway could influence weight gain, insulin resistance, hypertension, inflammation, and vascular dysfunction.

25 Jun 2026

Elite athletes with higher vitamin D show healthier lipid profiles

Higher serum 25-hydroxyvitamin D levels were independently associated with lower LDL-C, triglycerides, and lipoprotein(a) in 773 male professional athletes. The cross-sectional study cannot establish causality, but it suggests that vitamin D status may be linked to cardiovascular risk-related lipid markers, even in elite athletic populations.

23 Jun 2026

Statins may trigger muscle side effects by activating inflammatory danger signals

An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, reduced protein synthesis, and weakened muscle function.

22 Jun 2026

Oral semaglutide improves blood sugar, weight, and liver markers in real-world diabetes care

A nationwide Finnish registry study of 7,249 GLP-1RA-naïve adults with type 2 diabetes found that once-daily oral semaglutide was associated with 12-month improvements in HbA1c, body weight, lipid markers, and ALT.

11 Jun 2026

Obesity drug mazdutide reduces weight and waist size in major trial

Once-weekly 9 mg mazdutide produced clinically meaningful weight loss in Chinese adults with obesity, reducing body weight by 16.65% after 60 weeks versus 1.50% with placebo. The phase 3 GLORY-2 trial also found improvements in waist circumference, systolic blood pressure, and lipid markers, but gastrointestinal adverse events were common.

9 Jun 2026

Blood protein signature can predict lung cancer risk before diagnosis

Researchers at the Francis Crick Institute and University College London (UCL), funded by Cancer Research UK and the European Research Council (ERC), have identified a 14-protein signature in the blood that can predict lung cancer risk more than five years before diagnosis.

4 Jun 2026

How common spices may improve gut, brain, and metabolic health

The health effects of spices are explored, revealing their potential to influence blood sugar, inflammation, and brain function through various mechanisms.

28 May 2026

One-time gene editing cuts LDL cholesterol in early hypercholesterolemia trial

A phase 1 NEJM interim analysis found that a single infusion of the investigational base-editing therapy VERVE-102 produced dose-dependent reductions in circulating PCSK9 protein and LDL cholesterol in adults with heterozygous familial hypercholesterolemia or premature coronary artery disease.

26 May 2026

Ensitrelvir cuts household COVID-19 risk when given after exposure

Ensitrelvir, an oral SARS-CoV-2 3C-like protease inhibitor, reduced symptomatic RT-PCR-confirmed COVID-19 among household contacts when given within 72 hours after symptom onset in the infected index patient. In the phase 3 SCORPIO-PEP trial, COVID-19 occurred in 2.9% of ensitrelvir recipients versus 9.0% of placebo recipients, with similar overall adverse-event rates.

20 May 2026