Lupus Erythematosus News and Research

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Endometriosis linked to higher odds of autoimmune conditions

New research links endometriosis to autoimmune diseases, revealing shared mechanisms that may lead to earlier diagnosis and targeted treatments for patients.

23 Jun 2025

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of diseases, particularly cancers.

20 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

SLIRP protein identified as key regulator of immune responses

Even after the COVID-19 pandemic, various new infectious diseases continue to emerge, posing ongoing viral threats that demand robust and sustained immune defenses.

15 May 2025

Cardiovascular mortality higher in women with rheumatoid arthritis and lupus

Women with the autoimmune diseases rheumatoid arthritis, lupus or systemic sclerosis may have a higher rate of death related to cardiovascular disease than men with the autoimmune diseases, according to new research published in the American Heart Association's journal Circulation: Cardiovascular Quality and Outcomes.

6 May 2025

Mediterranean diet helps manage rheumatoid arthritis and Hashimoto’s, study shows

The Mediterranean diet shows promise in managing both systemic and organ-specific autoimmune diseases, including rheumatoid arthritis and autoimmune thyroiditis. Its anti-inflammatory and microbiota-modulating properties may reduce disease activity and improve metabolic outcomes.

23 Apr 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Fighting cancer, inflammation and unlocking dementia diagnostics

In recognition of their discovery of one of our immune system’s foundations, physician Andrea Ablasser, virologist Glen Barber and biochemist Zhijian J. Chen will be awarded the Paul Ehrlich and Ludwig Darmstaedter Prize 2025, endowed with €120,000, in Frankfurt’s Paulskirche today.

14 Mar 2025

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Lupus is an autoimmune disease where the body’s immune system attacks its own tissues and organs, causing inflammation and damaging organs.

12 Mar 2025

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

A new study of more than 2,900 patients provides evidence that it's likely best to use as little corticosteroid medicine as possible when treating people who have lupus pericarditis, a common heart complication of the autoimmune disease Systemic Lupus Erythematosus (SLE).

26 Feb 2025

Granzyme K identified as key trigger of complement system in autoimmune diseases

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that patrols our body, ever vigilant for signs of infection or injury

6 Feb 2025

Study uncovers why lupus patients have weaker response to COVID-19 vaccines

A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases.

16 Jan 2025

Dexter software platform reveals connection between early life trauma and immune disorders

University of Birmingham venture Dexter has demonstrated the power of its Dexter software platform in a study showing that people whose childhoods featured abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.

15 Jan 2025

Next-generation cell-penetrating antibodies could transform cancer treatment

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, 2024, titled "Advancements in cell-penetrating monoclonal antibody treatment."

11 Dec 2024

Women with infertility have higher risk of developing systemic autoimmune diseases

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

4 Dec 2024

Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

The Lupus Research Alliance (LRA) is excited to announce the first-ever recipients of the Translational Bridge Award (TBA), established this year to accelerate the translation of groundbreaking research into potential treatments and diagnostics for lupus.

8 Nov 2024

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

COVID-19 survivors may develop autoimmune conditions long-term, with risks varying by severity and vaccination status, necessitating continued health vigilance.

8 Nov 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

The Lupus Research Alliance (LRA), the largest private funder of lupus research worldwide, today announced that a total of 33 studies, funded by the organization or supported by its clinical research affiliate Lupus Therapeutics, will be presented at ACR Convergence 2024.

5 Nov 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research indicates elevated cardiovascular risk in vitiligo patients, underscoring the necessity for enhanced monitoring and preventive healthcare measures.

29 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024