Lymph Nodes News and Research

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Hidden viral reservoirs in tonsils may explain school-year respiratory outbreaks

A study conducted at the University of São Paulo (USP) in Brazil reveals that tissues such as the tonsils and adenoids can serve as hiding places for the rhinovirus, which causes the common cold and is responsible for most respiratory infections worldwide.

17 Apr 2026

New imager separates UV and infrared light to find cancerous nodes

Researchers have developed a compact camera that captures ultraviolet, near-infrared and visible images using a single chip. Inspired by the multiwavelength vision capability of the mantis shrimp, the camera could help surgeons identify lymph nodes connected to a tumor and assess whether cancer has spread to them, making cancer surgery safer and less invasive.

17 Apr 2026

Mitochondrial activity keeps dendritic cells ready to fight disease

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" state, linking cellular metabolism to gene regulation and T-cell activation.

15 Apr 2026

CAR T therapy induces remission in multiple autoimmune diseases

For the first time, scientists have used a cutting-edge cell therapy called CAR-T to treat a patient with three different life-threatening autoimmune diseases that had resisted years of treatment.

9 Apr 2026

Lung cancer scans can reveal signs of other undiagnosed cancers

When doctors review diagnostic medical scans for lung cancer, they sometimes spot abnormalities unrelated to the lungs.

31 Mar 2026

APOE4 alters brain immunity and cognition differently in females and males

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive vulnerability. Suppressing innate immunity improved some cognitive outcomes in female E4/E4 mice but worsened them in male E4/E4 mice, underscoring the need for sex-tailored approaches.

29 Mar 2026

Study reveals how inflammation disrupts lymph node structure in lymphoma

In aggressive lymphomas, inflammatory messengers reprogram the "conductors" of the immune system, causing lymph nodes structure to collapse.

26 Mar 2026

Circulating tumor DNA predicts breast cancer relapse after treatment

Fragments of tumor DNA circulating in the bloodstream of patients with breast cancer can predict whether they are likely to relapse, especially when samples are taken after the patients have received treatments prior to surgery.

26 Mar 2026

Immunotherapy plus chemotherapy improves outcomes in stage III dMMR colon cancer

A new study from researchers at the Alliance for Clinical Trials in Oncology (Alliance) shows that patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR) had significantly better outcomes when the immunotherapy drug atezolizumab (Tecentriq®) was added to standard chemotherapy after surgery.

25 Mar 2026

Breast cancer patients may avoid lymphedema with radiotherapy approach

Patients with breast cancer may be able to avoid lymphedema, which can occur after surgery to remove lymph nodes in the armpit (the axilla), by having radiotherapy instead.

25 Mar 2026

Personalized radiotherapy reduces the risk of breast cancer recurrence

The chances of breast cancer recurring remain very low when patients are treated with radiotherapy that is tailored to their individual risk following chemotherapy and surgery. These are the findings of a ten-year study presented at the 15th European Breast Cancer Conference (EBCC15) in Barcelona today (Wednesday).

24 Mar 2026

Redesigned lipid nanoparticles improve mRNA delivery to lymph nodes

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery to the liver.

24 Mar 2026

Modified lipid nanoparticles boost mRNA vaccines while reducing side effects

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever and general malaise.

17 Mar 2026

Geographic location strongly influences stage of breast cancer diagnosis

Where a woman lives significantly affects whether her breast cancer is diagnosed at an early or late stage, according to a national analysis published in the Journal of the American College of Surgeons (JACS).

11 Mar 2026

Minimally invasive ablation effective for early-stage kidney cancers

A large national study in Denmark following nearly 1,900 patients over almost a decade found that a minimally invasive procedure called ablation is as effective as surgery for treating small kidney cancers, with faster recovery and fewer complications. Results of the study were published today in Radiology, a journal of the Radiological Society of North America (RSNA).

3 Mar 2026

$8.7 million award supports faster genetic diagnosis of lymphatic diseases

A team of researchers led by Columbia University Vagelos College of Physicians and Surgeons has been awarded an up to two-year $8.7 million contract from the Advanced Research Projects Agency for Health (ARPA-H) to create genetic tests to speed the diagnosis of patients born with defects in the lymphatic system.

19 Feb 2026

Preoperative combination treatment shows promise for some patients with pancreatic cancer

A new UCLA investigator-initiated study sponsored by the UCLA Health Jonsson Comprehensive Cancer Center has found that adding immunotherapy to standard chemotherapy before surgery is safe and shows promise for some patients with borderline-resectable pancreatic cancer, a disease that has historically been difficult to treat.

17 Feb 2026

Trial highlights promising frontline therapy for blastic plasmacytoid dendritic cell neoplasm

Seventy-five percent of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) who were treated with the antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) had a complete response, according to new data from the Phase I/II multicenter international CADENZA trial led by researchers at The University of Texas MD Anderson Cancer Center.

11 Feb 2026

Engineered CAR-T cells reduce Alzheimer’s plaques in mice

Chimeric antigen receptor (CAR) T cell therapy, a type of immunotherapy that leverages the immune system to combat diseases, is a powerful treatment option for certain cancers.

9 Feb 2026

Study reveals evidence of silent mpox exposure in healthy Nigerians

New evidence suggests that mpox may be circulating quietly among healthy Nigerians, with some infections occurring without the symptoms that typically trigger detection by health authorities.

5 Feb 2026