Metabolic Disease News and Research

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Uninherited parental genes leave lasting imprint on children's lives

Our parents' genes, even the ones we didn't inherit, leave a measurable lasting imprint on our lives. An international team led by researchers at the Institute of Science and Technology Austria (ISTA) and the Norwegian Institute of Public Health developed a new approach to analyze genetic data from tens of thousands of families.

9 Jun 2026

Tobacco giants helped push ultra-processed foods into global markets

New research reveals how major tobacco companies used cigarette-era business tactics to expand packaged food empires, raising fresh questions about the global spread of ultra-processed and hyper-palatable foods.

4 Jun 2026

Continuing gout therapy during remission lowers future flare risk

The European Alliance of Associations for Rheumatology - held its 2026 annual Congress in London, where gout was high on the agenda.

3 Jun 2026

GLP-1 treatments may reduce knee replacement surgery rates

GLP-1 receptor agonist drugs, used for the treatment of diabetes, and more recently, weight loss, are associated with a significantly lower long term risk of knee replacement surgery as a result of osteoarthritis, finds an analysis of medical records data, published in the open access journal Regional Anesthesia & Pain Medicine.

2 Jun 2026

Gut microbes may reveal who is at risk of type 2 diabetes years before diagnosis

A large Swedish prospective cohort study found that specific gut microbial species and metabolic pathways measured years before diagnosis were associated with future type 2 diabetes risk. The findings suggest that gut microbiome composition and functional potential may help explain T2D development, but replication is needed before clinical use.

28 May 2026

LSU study examines how restrained sitting limits early childhood movement

Researchers at LSU's Pennington Biomedical Research Center, in collaboration with investigators from 32 countries participating in the SUNRISE International Study, have published new findings examining how restrained sitting contributes to daily movement patterns in early childhood.

28 May 2026

Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence

The review highlights nanocarriers, microspheres, hydrogels, microneedles, long-acting formulations, and co-formulations as promising but mostly early-stage strategies that still require stronger long-term clinical evidence.

27 May 2026

True toll of long COVID may be double that of current estimates, research shows

The true toll of long COVID may be double that of current estimates and hidden from current surveillance systems that rely on capturing diagnostic codes, according to new research led by Mass General Brigham.

27 May 2026

Pennington and Vanderbilt launch major study on childhood obesity treatment

Pennington Biomedical Research Center, in collaboration with Vanderbilt University Medical Center, has launched a research study, the COACH trial, to test different ways to help children and their families improve their health through lifestyle changes delivered by primary care clinics in communities in Louisiana and Tennessee.

19 May 2026

Pregnancy-related disorders may shape offspring heart health into adulthood

Hypertensive disorders in pregnancy may lead to lasting cardiovascular issues in offspring, highlighting the need for improved maternal health strategies.

19 May 2026

Researchers use living human cells on a chip to study memory loss

A University of Bath-led project has secured £500,000 to develop a first-of-its-kind 'organ-on-chip' device that replicates connections between the brain, gut and pancreas.

19 May 2026

Adding GLP-1 drugs to behavioral interventions silences food noise

New research presented at this year's European Congress on Obesity in Istanbul, Turkey, shows that use of obesity drugs alongside behavioral interventions leads to a larger drop in so called 'food noise' than in those using the behavioral therapy alone.

13 May 2026

Why is the US falling behind other high-income nations on survival?

A JAMA Network Open study found that the US recorded 12.7 million excess deaths compared with 17 peer high-income countries between 1999 and 2022. Circulatory and metabolic diseases drove much of the burden, while drug poisonings, alcohol-related deaths, and suicide sharply widened the gap among younger Americans.

12 May 2026

Cannabis compounds may improve metabolism and reduce diabetes risk

A University of California, Riverside preclinical study is shedding light on a long-observed but poorly understood phenomenon: chronic cannabis users tend to have lower body weight and a reduced risk of developing type 2 diabetes, despite the drug's well-known tendency to increase appetite.

11 May 2026

Urges for cardiologists to screen patients for UPF intake

The European Society of Cardiology identifies ultra-processed foods as a key cardiovascular risk, urging a shift in dietary guidelines for better heart health.

11 May 2026

Asthma medication formoterol shows promise for treating fatty liver disease

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide.

8 May 2026

UK restaurant chains miss most government sugar and salt targets

A study reveals low adherence to UK nutrition targets in major restaurant chains, raising concerns about dietary risks for cardiovascular disease and diabetes.

8 May 2026

Six genes found to connect pancreatic cancer with metabolic dysfunction

New research shows that the same genes are active in pancreatic cancer, obesity and diabetes, helping to explain why people with metabolic disease often face poorer cancer outcomes and pointing to future ways to predict recurrence and develop more targeted treatments.

6 May 2026

Exercise remains essential alongside GLP-1 obesity treatments

As GLP-1 receptor agonists reshape obesity treatment, a new medical perspective published in the Journal of the American Medical Association, or JAMA, underscores a persistent gap in care: integrating exercise into weight management in ways patients can sustain.

5 May 2026

Obesity and Alzheimer’s linked through early metabolic disruptions

By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease (AD), affecting about 1 in 9 adults over 65.

5 May 2026