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New study uncovers bacterial route to testosterone production

Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects.

4 Sep 2026

Mitochondrial stress triggers long-term protection against heart damage

Mitochondria are popularly known as the "powerhouse of the cell," but these cellular structures do so much more-including acting as signaling hubs.

4 Sep 2026

Gut bacterial metabolite linked to inflammation in liver disease

Researchers have identified a link between specific activities in gut bacteria and the liver disease PSC.

4 Sep 2026

Gut bacterial molecule discovered to drive serious bile duct disease

Researchers at the University of Oslo and Oslo University Hospital have, together with international collaborators, discovered that a small molecule made exclusively by gut bacteria can actively drive disease in the bile ducts and worsen primary sclerosing cholangitis (PSC), a serious liver and bile duct disease.

4 Sep 2026

Extreme long-distance running triggers major surge in body's cannabis-like molecules

A marathon, 100 kilometers or even 230 kilometers in one go: Anyone running such distances puts enormous strain on their body.

4 Sep 2026

The obesity-microbiome story is more complicated than ‘good’ and ‘bad’ bacteria

This review finds that obesity is linked to reciprocal interactions between diet, the gut microbiome, microbial metabolites, and host metabolic pathways that influence appetite, insulin sensitivity, inflammation, and energy balance across the lifespan. It highlights diet as a particularly tractable way to influence this system, while emphasizing that microbiome changes associated with GLP-1 therapies remain difficult to separate from weight loss and that functional multi-omics approaches may help enable more personalized interventions.

3 Sep 2026

Cancer-fighting T cells need small amounts of ROS to attack tumors, study finds

New research reveals a promising new target for treating cancer by harnessing a type of molecule previously thought to do more harm than good.

3 Sep 2026

Shared biological pathways may explain chronic fatigue across diseases

A shared biological secret that helps explain chronic exhaustion in conditions including long Covid and PTSD has been discovered by researchers at the University of East Anglia and Oxford BioDynamics.

2 Sep 2026

Blocking a naturally occurring molecule reverses deadly lung disease in preclinical models

Researchers blocked a naturally occurring molecule to reverse pulmonary arterial hypertension in preclinical models, a finding that could point to a new treatment approach for people with a rare and often fatal lung disease.

2 Sep 2026

Cellular atlas offers clues to childhood Crohn’s treatment response

Researchers have created a detailed map of childhood Crohn's disease before and after treatment to help understand progression of the disease.

1 Sep 2026

New tool amplifies and visualizes tiny protein changes

Imagine a brain teaser where the challenge is to spot the difference between two nearly identical sandcastles.

1 Sep 2026

Study reveals how melanoma weakens skin cell immune defenses

Cancers actively remodel their surrounding cells and tissues to create a microenvironment that favors their growth, survival, and spread.

1 Sep 2026

Modified AlphaFold3 successfully predicts complex protein conformational changes

Conformational changes in proteins are vital to their function yet remain challenging for state-of-the-art artificial intelligence, such as AlphaFold3, to predict.

1 Sep 2026

BeOne Medicines announces voluntary agreement with U.S. Government to expand access to innovative cancer medicines

BeOne Medicines, Ltd., a global oncology company, today announced a voluntary agreement with the U.S. Government to expand access to innovative cancer medicines for American patients while strengthening our U.S manufacturing footprint and further expanding the capabilities needed to deliver medicines at scale.

1 Sep 2026

Newly discovered lung immune cells could transform future flu vaccine design

Influenza continues to cause major illness each year in the United States, leading to more than 35,000 deaths annually. Children, older adults, pregnant individuals, people with weakened immune systems, and those with chronic conditions such as heart disease, metabolic disorders, and cancer are especially vulnerable.

31 Aug 2026

Experts call for safer weight loss as concerns grow over GLP-1 use

An editorial in Diabetology International argues that inappropriate GLP-1 use should be judged not only by regulatory compliance or off-label prescribing, but also by whether weight reduction is medically safe, nutritionally adequate, and properly supervised. Drawing on Japanese reports of ketosis and ketoacidosis following inappropriate tirzepatide use, the authors call for greater attention to the risks of unsafe weight-loss practices alongside medication-related harms.

30 Aug 2026

Newly developed radiotheranostic pair identifies and treats renal tumors

A newly developed radiotheranostic pair, 68Ga/177Lu-NYM096, can identify tumors and effectively deliver targeted radiotherapy to patients with metastatic clear cell renal cell carcinoma (ccRCC).

28 Aug 2026

Study reveals how SGLT2 inhibitors improve failing heart function

Researchers have discovered that SGLT2 inhibitors, a class of drugs originally developed to treat diabetes and now widely used for heart failure, work by activating a key enzyme that helps heart cells produce and use energy more efficiently.

27 Aug 2026

Scientists reviewed 20 edible and medicinal fungi for clues to better prebiotics

A review of 20 non-toxic edible and medicinal fungal species found that their polysaccharides can resist digestion, interact with gut microbes, and influence microbial metabolites linked to intestinal and metabolic health. The evidence suggests potential benefits for conditions including colitis, type 2 diabetes, and obesity, although most findings currently come from laboratory and animal studies.

27 Aug 2026

Unexpected discovery points to a possible route for childhood brain tumor treatments

When researchers at Lund University investigated how the molecule UM171 works, a molecule used to make blood stem cells multiply, they made an unexpected connection.

27 Aug 2026