Opioids News and Research

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An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects and the side effects of opioids.

New tool helps identify fake medicines through pill dissolution patterns

Fake news can be tricky to spot, but spotting fake drugs just got a little easier. Researchers have devised a low-cost way to help distinguish legitimate medications from counterfeit ones.

19 Mar 2026

Maker of device to treat addiction withdrawal seeks counties’ opioid settlement cash

In the early 2000s, Michelle Warfield worked at a factory, hauling heavy seats for Ford trucks on and off an assembly line. To suppress daily aches in her back and hips, her doctor prescribed opioid painkillers.

18 Mar 2026

Weekly buprenorphine injections improve opioid abstinence during pregnancy

In a clinical trial supported by the National Institutes of Health (NIH), a research team found that administering weekly injectable extended-release buprenorphine for treatment of opioid use disorder (OUD) during pregnancy led to higher rates of abstinence from illicit opioids than buprenorphine given daily under the tongue (sublingual), one of the standard methods of treatment.

16 Mar 2026

New release Wiley's Mass Spectra of Designer Drugs 2026 expands coverage of emerging novel psychoactive substances

Wiley, a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation and learning, today announced the 2026 release of Mass Spectra of Designer Drugs, the essential GC‑MS spectral database used by forensic laboratories worldwide for the rapid identification of illicit substances.

From John Wiley and Sons - Scientific Publishers 16 Mar 2026

Cannabis, cocaine and amphetamines linked to higher stroke risk

Cannabis and other illicit drugs are associated with higher stroke risk, underscoring the importance of addressing substance use disorders in health strategies.

11 Mar 2026

Could GLP-1 drugs help curb addiction? Large veteran study points to potential benefit

A large cohort study of more than 600,000 US veterans with type 2 diabetes found that initiating GLP-1 receptor agonists was associated with lower risks of developing substance use disorders compared with SGLT-2 inhibitors. Among veterans with existing substance use disorders, GLP-1 receptor agonist use was also linked to fewer overdose events, hospitalizations, and suicide-related outcomes.

8 Mar 2026

GLP-1 drugs may be effective at treating and preventing substance use disorders

Researchers at Washington University School of Medicine in St. Louis show in a new study that GLP-1 medications may be effective at treating and preventing substance use disorders across all major addictive substances studied, suggesting these drugs target a common biological pathway underlying addiction.

4 Mar 2026

UCF researcher explores insulin signaling as new target for diabetic neuropathy

Neuropathy – chronic pain, numbness and tingling in the hands and feet – is a challenging fact of life for many patients with Type 1 diabetes.

2 Mar 2026

NIH’s continued investment fuels TMJ pain research

Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported type, followed closely by head and face pain linked to the jaw joint, in the form of temporomandibular joint (TMJ) disorder.

27 Feb 2026

Study finds sharp drop in benzodiazepine use among older adults

Benzodiazepine treatment declined among U.S. adults between 2018 and 2022, with the steepest drop among adults ages 56 and older, according to a new study by researchers at the Columbia University Mailman School of Public Health and Columbia University Irving Medical Center.

25 Feb 2026

Opioids offer limited short-term relief for acute pain

The world's largest review of opioid pain relievers prescribed for acute pain found these medicines provide only small, short-term relief for some acute conditions and are ineffective for some others.

25 Feb 2026

Study finds widespread off-label use of antipsychotics among older people

The use of antipsychotic medications for purposes other than those officially approved is common among older adults in Finland.

23 Feb 2026

As more Americans embrace anxiety treatment, MAHA derides medications

After a grueling year of chemotherapy, surgery, and radiation to treat breast cancer, Sadia Zapp was anxious — not the manageable hum that had long been part of her life, but something deeper, more distracting.

23 Feb 2026

Cannabis legalization may lead to a decline in daily opioid use

Legalizing cannabis for both medical and recreational use may lead to a decline in daily opioid use among people who inject drugs in the United States, according to a new study led by a Boston University School of Public Health researcher (BUSPH).

9 Feb 2026

Research sheds light on the UK's growing synthetic opioid problem

Deaths due to synthetic opioids nitazenes have likely been underestimated by up to a third.

9 Feb 2026

Electroacupuncture relieves pain-induced anxiety through prefrontal neural circuits

Neuropathic pain, caused by injury or disease of the somatosensory nervous system, is a major clinical challenge and often evolves into a chronic condition.

7 Feb 2026

Preoperative factors predict persistent opioid use after surgery

For many Americans, a routine surgical procedure serves as their first introduction to opioid pain medication.

5 Feb 2026

Artificial intelligence enables faster detection of substance use disorder

Diagnosing substance-use disorder can be difficult because of patient denial related to the stigma attached to addiction.

5 Feb 2026

Smartwatch data may help detect opioid misuse risk

Opioid overdoses continue to take a devastating toll across the United States. According to the U.S. Centers for Disease Control and Prevention (CDC), in 2023, the nation recorded roughly 105,000 drug overdose deaths overall, with nearly 80,000 deaths involving opioids.

5 Feb 2026