Retinopathy News and Research

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AI algorithm proves more accurate than experts in glaucoma detection

While artificial intelligence (AI)-powered screening has been validated for diabetic retinopathy, applying the technology to glaucoma has proved more challenging because glaucoma is not one disease. A glaucoma diagnosis is based on a constellation of symptoms, diagnostic tests, and longitudinal data.

22 Oct 2025

Live retinal imaging uncovers early signs of diabetic eye disease

A new method of taking microscopic images of a live mouse's retina through the eye allows to record the reaction of brain cells to disease and treatment.

6 Oct 2025

Precision probiotics lower blood sugar and cholesterol in mice

Researchers developed a precision probiotic cocktail comprising three Lactobacillus strains that improved glucose control, reduced weight gain, and lowered cholesterol levels in mice fed a high-fat diet. Metabolomic and microbiome analyses revealed host metabolic adaptations and beneficial shifts in gut bacteria, highlighting translational potential for future clinical trials.

28 Sep 2025

New eyedrop raises hopes for less invasive treatment of serious vision conditions

A new eyedrop has shown early success in delivering protective compounds to where they're needed most in the eye, raising hopes for less invasive treatment of serious vision conditions.

22 Sep 2025

Holder vs Retort: How milk pasteurization shapes preterm infants’ gut health

Researchers at Vanderbilt University Medical Center found that pasteurization methods shape the gut microbiomes of preterm infants fed donor human milk. Holder pasteurization preserved microbial diversity and beneficial taxa better than Retort, producing microbiomes more similar to those from mothers’ own milk.

17 Sep 2025

Tai chi improves memory and sleep in older adults with type 2 diabetes

A 12-week randomized trial found that remotely delivered Tai Chi significantly enhanced cognitive performance and sleep quality in older adults with Type 2 Diabetes. These gains surpassed those from supervised fitness walking or usual care, without increasing adverse events.

17 Sep 2025

GLP-1 drugs found to protect against diabetic retinopathy

GLP-1 receptor agonist drugs protect against diabetic retinopathy, a common complication of diabetes that can lead to sight loss, suggests new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Pharmaceutics.

17 Sep 2025

Cleveland Clinic study shows lasting benefits of weight-loss surgery over GLP-1 medicines

A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo weight-loss surgery live longer and face fewer serious health problems compared with those treated with GLP-1 receptor agonist medicines alone.

16 Sep 2025

SLIT2 protein levels in the eye and blood linked to cognitive function

Neurocognitive impairments are classified by pathological changes with potential for destruction of neural tissue. One change known to occur in neurodegenerative disorders is an accumulation of proteins causing pathological damage.

11 Sep 2025

Faster progression to severe diabetes observed in people with learning disabilities

People with learning disabilities progress faster to severe type 2 diabetes and are at greater risk of dying from their condition than people without these disabilities, suggests research published in the open access journal BMJ Open Diabetes Research & Control.

2 Sep 2025

Heparanase 2 emerges as key protector of blood vessel integrity

An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessels' integrity.

2 Sep 2025

Research shows GLP-1 drugs safeguard vision despite small retinopathy risk

A large study of over 185,000 adults with type 2 diabetes found that GLP-1 receptor agonist use was linked to a slight increase in new diabetic retinopathy cases but fewer severe eye complications, including a reduced risk of blindness. Patients with existing retinopathy on these drugs also needed fewer invasive eye treatments over two years.

13 Aug 2025

Exonate plans 'CLEAR-DE' Phase IIb clinical trial of lead candidate EXN407 for diabetic eye disease

Exonate Ltd., a biotechnology company developing novel, non-invasive, small-molecule therapeutics for patients with retinal vascular diseases, today announced plans to initiate a Phase IIb clinical trial for its lead candidate EXN407.

29 Jul 2025

Novel AI-powered retina tracker detects eye disease in under one second

A novel AI-powered retina tracker can analyze retinal images with near-perfect accuracy in under one second, according to a study being presented Monday at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif.

15 Jul 2025

Why vitamin B6 could raise the risk of hypoglycemia for people with diabetes

A large-scale Mendelian randomization study found no genetic evidence that vitamins A, C, or D reduce the risk of major diabetic complications. However, higher genetically predicted vitamin B6 levels were strongly associated with increased risk of diabetic hypoglycemia, warranting caution with supplementation.

8 Jul 2025

Targeting ADAM10 may offer hope for retinal disease treatment

New research has found that the endothelial cell-specific A disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) regulates abnormal blood vessel growth in the damaged retina, which can cause vision loss or impairment.

25 Jun 2025

How early-life factors raise lifelong diabetes risks in youth

The surge in diabetes among young people highlights critical gaps in care and the urgent need for comprehensive preventative actions to address this crisis.

19 Jun 2025

Microfluidic contact lenses emerge as next generation tools for eye care

The tear film coating the eye offers a window into a person's systemic and ocular health, carrying biomarkers such as glucose, electrolytes, and proteins.

31 May 2025

NIH grant supports Wayne State University research on protecting vision in people with diabetes

A four-year, $2.33 million grant from the National Eye Institute of the National Institutes of Health to Wayne State University is supporting research focused on improving and preserving vision and eye health in those with diabetes.

13 May 2025

How urine caffeine levels may help detect diabetic eye damage early

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANES 2009–2014 data and highlights potential biomarkers for early detection in diabetic populations.

7 May 2025