Systemic Lupus Erythematosus News and Research

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Systemic lupus erythematosus (SLE) is the form of the disease that most people are referring to when they say "lupus." The word "systemic" means the disease can affect many parts of the body. The symptoms of SLE may be mild or serious. Although SLE usually first affects people between the ages of 15 and 45 years, it can occur in childhood or later in life as well.

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Lupus is an autoimmune disease where the body’s immune system attacks its own tissues and organs, causing inflammation and damaging organs.

12 Mar 2025

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

A new study of more than 2,900 patients provides evidence that it's likely best to use as little corticosteroid medicine as possible when treating people who have lupus pericarditis, a common heart complication of the autoimmune disease Systemic Lupus Erythematosus (SLE).

26 Feb 2025

Granzyme K identified as key trigger of complement system in autoimmune diseases

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that patrols our body, ever vigilant for signs of infection or injury

6 Feb 2025

Study uncovers why lupus patients have weaker response to COVID-19 vaccines

A recent study by Emory University researchers provides new insights into why the mRNA vaccines developed to fight COVID-19 in 2021 are less effective in patients with autoimmune diseases.

16 Jan 2025

Dexter software platform reveals connection between early life trauma and immune disorders

University of Birmingham venture Dexter has demonstrated the power of its Dexter software platform in a study showing that people whose childhoods featured abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.

15 Jan 2025

Next-generation cell-penetrating antibodies could transform cancer treatment

A news feature on the research paper "Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition" by Rackear et al. was published in Oncotarget's Volume 15 on November 22, 2024, titled "Advancements in cell-penetrating monoclonal antibody treatment."

11 Dec 2024

Women with infertility have higher risk of developing systemic autoimmune diseases

Women who experience infertility but do not use fertility treatments have a higher risk of developing a group of conditions called systemic autoimmune rheumatic diseases (SARD) in the nine years after a naturally conceived birth compared to women without fertility problems.

4 Dec 2024

Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

The Lupus Research Alliance (LRA) is excited to announce the first-ever recipients of the Translational Bridge Award (TBA), established this year to accelerate the translation of groundbreaking research into potential treatments and diagnostics for lupus.

8 Nov 2024

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

COVID-19 survivors may develop autoimmune conditions long-term, with risks varying by severity and vaccination status, necessitating continued health vigilance.

8 Nov 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

The Lupus Research Alliance (LRA), the largest private funder of lupus research worldwide, today announced that a total of 33 studies, funded by the organization or supported by its clinical research affiliate Lupus Therapeutics, will be presented at ACR Convergence 2024.

5 Nov 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

Research indicates elevated cardiovascular risk in vitiligo patients, underscoring the necessity for enhanced monitoring and preventive healthcare measures.

29 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

Systemic Lupus Erythematosus News and Research

Understanding the role of iron-dependent ferroptosis in immune suppression

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

Granzyme K identified as key trigger of complement system in autoimmune diseases

Study uncovers why lupus patients have weaker response to COVID-19 vaccines

Dexter software platform reveals connection between early life trauma and immune disorders

Next-generation cell-penetrating antibodies could transform cancer treatment

Women with infertility have higher risk of developing systemic autoimmune diseases

Lupus Research Alliance launches first Translational Bridge Award to accelerate lupus treatments

Link between COVID-19 and long-term risk of autoimmune and autoinflammatory connective tissue disorders

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

Vitiligo linked to increased risk of heart disease and stroke, study finds

New study reveals mechanism of inflammation in lupus

The new science behind the health benefits of caffeine

Caffeine's anti-inflammatory effects may help protect blood vessels

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Autoimmune diseases more common in women who stop ovulating before 40

Over 80% of women are iron deficient by their third trimester

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Lupus Research Alliance announces 2024 Diversity in Lupus Research Award recipients

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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