Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when cultured outside the diabetic environment. This recovery, driven by specific gene expression changes, identifies JAK inhibitors as potential therapeutic candidates to restore β-cell function.

14 Oct 2025

Skipping breakfast raises metabolic syndrome risk

Research shows that skipping breakfast increases the risk of metabolic syndrome, emphasizing the need for a nutritious morning meal to support long-term health.

13 Oct 2025

Home blood tests could spot early heart risks in young adults

Self-administered dried blood spot kits show potential for cardiometabolic screening in young adults, but success relied heavily on clear guidance and researcher support. High rates of at-risk biomarkers highlight an urgent need for early prevention in this population.

12 Oct 2025

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumor growth.

9 Oct 2025

Using a lab-designed protein to regulate blood glucose levels

Researchers at the Indiana University School of Medicine have discovered a new way to regulate blood glucose levels using a lab-designed protein, possibly opening the door to a new treatment avenue for people with Type 1 diabetes.

9 Oct 2025

Diabetic teens with poor glycemic control more likely to develop neuropathy in adulthood

Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes, research co-led by University of Michigan suggests.

9 Oct 2025

Air pollution plays a significant role in the development of metabolic disorders

Long-term exposure to fine air pollution can impair metabolic health by disrupting the normal function of brown fat in mice. A study co-led by the University of Zurich shows that this occurs through complex changes in gene regulation driven by epigenetic mechanisms.

9 Oct 2025

Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin-a critical hormone that regulates blood sugar in the body.

8 Oct 2025

Depression during pregnancy raises risk of gestational diabetes

Findings indicate that antenatal depression increases the risk of gestational diabetes, underscoring the need for early intervention and lifestyle support.

8 Oct 2025

Healthy diet may double life expectancy benefits for frail adults

Research shows that improved diet quality significantly enhances life expectancy in frail older adults, highlighting the importance of nutrition in aging.

8 Oct 2025

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has revealed.

7 Oct 2025

SMOC1 gene plays a surprising role in the development of type 2 diabetes

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S., and a leading research center for diabetes and other life-threatening illnesses, have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into those that increase blood sugar.

7 Oct 2025

Exercise beats yoga for improving heart and blood vessel health

Researchers compare the effects of physical exercise and yoga on cardiovascular function.

7 Oct 2025

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

A major new study reveals that both sugar-sweetened beverages (SSBs) and low- or non-sugar-sweetened beverages (LNSSBs) are significantly associated with a higher risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD).

6 Oct 2025

Visceral fat activity linked to advanced endometrial cancer

High metabolic activity of visceral fat may be associated with more aggressive endometrial cancer, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has shown.

5 Oct 2025

Elderberry juice boosts key genes for metabolic flexibility in overweight adults

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight adults during meal challenges.

3 Oct 2025

Exploring exercise's physiological response to fight diabetes

Don't love the gym? Neither does exercise scientist Ryan Montalvo. But he goes anyway. While any workout can seem daunting, the physical stress of exercise often affords long-term benefits. One advantage is that it triggers a physiological response that allows our cells to adjust to meet future energy demand in what's known as a hormetic response.

3 Oct 2025

New tool enables and enhances protein investigations

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators. The technology should enable and enhance investigations in both fundamental biology and disease research.

3 Oct 2025

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with diabetes and help them avoid dangerous hypoglycemia.

3 Oct 2025

Prediabetes can go into remission without weight loss

Research shows up to 22% of prediabetic individuals achieve remission without weight loss, emphasizing metabolic health over weight loss in diabetes prevention.

2 Oct 2025

Insulin News and Research

Further Reading

Scientists revive diabetic beta cells, revealing a new path to restore insulin function

Skipping breakfast raises metabolic syndrome risk

Home blood tests could spot early heart risks in young adults

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Using a lab-designed protein to regulate blood glucose levels

Diabetic teens with poor glycemic control more likely to develop neuropathy in adulthood

Air pollution plays a significant role in the development of metabolic disorders

Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Depression during pregnancy raises risk of gestational diabetes

Healthy diet may double life expectancy benefits for frail adults

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

SMOC1 gene plays a surprising role in the development of type 2 diabetes

Exercise beats yoga for improving heart and blood vessel health

Artificially-sweetened and sugary drinks linked to higher risk of non-alcoholic fatty liver disease

Visceral fat activity linked to advanced endometrial cancer

Elderberry juice boosts key genes for metabolic flexibility in overweight adults

Exploring exercise's physiological response to fight diabetes

New tool enables and enhances protein investigations

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

Prediabetes can go into remission without weight loss

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