Asthma News and Research

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Asthma is a common inflammatory disease affecting the airways that leads to shortness of breath, coughing and wheezing. Symptoms range from mild to severe but are generally manageable with appropriate treatment.

Some commonly used drugs cause bone loss: New research

New research helps to explain why some commonly used drugs come with a serious downside: They up your odds of breaking a bone. The drugs in question, glucocorticoids (e.g. cortisone and prednisone) and the insulin sensitizer rosiglitazone work through entirely different mechanisms as therapies for inflammatory diseases and diabetes respectively, and two studies in the June issue of Cell Metabolism now show that they lead to bone loss in different ways too.

9 Jun 2010

In the news: Senate and jobs bill; Obama appeals to seniors; States' Medicaid squeeze; Beyond COBRA

Today's headlines highlights President Obama's planned visit to a senior center to tout health reform, while several columns examine insurance issues, what doctors say about electronic medical record goals and military treatment of traumatic brain injuries is investigated.

9 Jun 2010

NexGen Biomedical offers RNAi / PSR platform technology for sale

NexGen Biomedical, Inc. announced today that it is offering its RNAi / PSR platform technology for sale. "While technologies like siRNA are well suited for disease conditions involving expression of a single protein, the RNAi / PSR technology is better suited for conditions involving expression of a broad spectrum of proteins such as happens with cell hyperproliferation, inflammation, and viral infections.

8 Jun 2010

Aerovance reports top-line results from Aerovant Phase 2b clinical trial for eosinophilic asthma

Aerovance Inc. today announced top-line results from its Phase 2b clinical trial that show the inhaled dry powder formulation of Aerovant (pitrakinra inhalation powder) is effective in a pre-defined subset of patients with eosinophilic asthma.

8 Jun 2010

Boosting levels of ABCG1 protein in diabetics will improve insulin production

If you think of diabetes onset like an elaborate molecular drama, then a research team led by a La Jolla Institute scientist has unmasked a previously unknown cellular player, which is critical to proper insulin secretion. "Defective insulin secretion is a hallmark of both type 1 and type 2 diabetes," said Catherine Hedrick, Ph.D., a scientist at the La Jolla Institute for Allergy & Immunology, who led the team, which included researchers from the University of Virginia.

8 Jun 2010

La Jolla Institute scientist finds protein key to insulin secretion

8 Jun 2010

Report finds racial and ethnic disparities in children's health and health care

Within a comprehensive health insurance system, black and Hispanic children appear more likely than white children to have asthma and their outcomes are often worse, according to a report posted online today that will appear in the August print issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

8 Jun 2010

Guardian Home Care Holdings, Cardiocom provide home telehealth technology to patients with chronic illnesses

Guardian Home Care Holdings, Inc., a leading provider of home care and hospice services, announced it has entered into a business relationship with Cardiocom to provide advanced home telehealth technology to patients with chronic illnesses. Cardiocom is a developer, manufacturer and clinical service provider of award-winning telehealth solutions.

7 Jun 2010

EDEMA4 study results of KALBITOR for treatment of acute attacks of HAE published

Dyax Corp. announced today the publication of results from its second Phase 3, placebo-controlled trial, known as EDEMA4, evaluating KALBITOR (ecallantide) for the treatment of acute attacks of hereditary angioedema. The results, published in the June 2010 issue of the Annals of Allergy, Asthma, and Immunology, indicate that KALBITOR is effective in ameliorating HAE attacks, resolving associated symptoms and preventing attack progression.

7 Jun 2010

Smoke-free laws protect both children and adults from exposure to secondhand smoke

Researchers at the Harvard School of Public Health (HSPH) have found that children and adolescents living in non-smoking homes in counties with laws promoting smoke-free public places have significantly lower levels of a common biomarker of secondhand smoke exposure than those living in counties with no smoke-free laws.

7 Jun 2010

Study sheds light on how IMT improves performance in endurance sports

An Indiana University study found that strengthening inspiratory muscles by performing daily breathing exercises for six weeks significantly reduced the amount of oxygen these same breathing muscles required during exercise, possibly making more oxygen available for other muscles.

4 Jun 2010

Unhealthy diet and lifestyle linked to childhood asthma - study

Asthma in children is on the rise worldwide and scientists have often blamed the environment for this trend. Britain has more than 1.1 million children and the US has nearly 10 million children with asthma. In a new international study diet has been cited to be a factor that affects asthma in children. The study on Allergies and Asthma in Childhood has shown what many parents knew for a while now – burgers are not good for children.

3 Jun 2010

FDA issues letter directing GSK to revise product labeling for Serevent and Advair

GlaxoSmithKline today announced that it has received a letter from the U.S. Food and Drug Administration directing revisions to product labeling for its respiratory products Serevent and Advair. The letter concludes discussions between GSK and the agency following FDA advisory committee meetings regarding the safety profile of long-acting beta2-agonists in the treatment of asthma, including salmeterol, the active ingredient in Serevent and one of the active ingredients in Advair.

3 Jun 2010

Top physicians offer health advice to help people survive during summer

This summer a variety of top physicians at NewYork-Presbyterian Hospital are offering health advice to help survive the travails that come with one of the most active seasons of the year.

3 Jun 2010

Entelos' T1D PhysioLab platform published in Clinical and Experimental Immunology

Entelos, Inc. has announced a publication in the peer-reviewed journal Clinical and Experimental Immunology describing the Type 1 Diabetes (T1D) PhysioLab® platform, an in silico solution for rapidly streamlining preclinical research through the evaluation of alternative scenarios for therapeutic strategies.

2 Jun 2010

Centocor Ortho Biotech acquires RespiVert

Centocor Ortho Biotech Inc. today announced that it has acquired RespiVert Ltd., a privately held drug discovery company focused on developing small-molecule, inhaled therapies for the treatment of pulmonary diseases. The company's lead compounds, RV-568 and RV-1088, narrow spectrum kinase inhibitors with a unique profile of anti-inflammatory activities, are progressing into clinical development as potential first-in-class treatments for moderate to severe asthma, Chronic Obstructive Pulmonary Disease (COPD) and Cystic Fibrosis (CF).

1 Jun 2010

Allergic reactions prevent people with allergic asthma from generating healthy immune response to influenza

New research from UT Southwestern Medical Center suggests that allergic reactions to pet dander, dust mites and mold may prevent people with allergic asthma from generating a healthy immune response to respiratory viruses such as influenza.

29 May 2010

One-quarter of all hospital patients experience readmission for same conditions: AHRQ

Roughly one-quarter of all hospital patients were readmitted over a two-year period for the same conditions that prompted their initial hospitalization, according to the latest News and Numbers by the Agency for Healthcare Research and Quality.

28 May 2010

Weill Cornell Medical College commences construction of 18-story, $650 million Medical Research Building

Weill Cornell Medical College today celebrated the start of construction on its new Medical Research Building, a state-of-the-art facility that will more than double the institution's existing research space. The 18-story, $650 million building is the centerpiece of Weill Cornell's $1.3 billion Discoveries that Make a Difference Campaign, the country's largest for a medical college. A total of $1 billion has been raised toward this goal in a record time of less than four years.

27 May 2010

Amira announces UK patent grant for heteroalkyl antagonists of prostaglandin D2 receptors

Amira Pharmaceuticals, Inc. today announced that the U.K. Intellectual Property Office has granted patent number GB2461629, titled, "HETEROALKYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS," which includes coverage of Amira's AM461 DP2 receptor antagonist.

27 May 2010

Asthma News and Research

Further Reading

Some commonly used drugs cause bone loss: New research

In the news: Senate and jobs bill; Obama appeals to seniors; States' Medicaid squeeze; Beyond COBRA

NexGen Biomedical offers RNAi / PSR platform technology for sale

Aerovance reports top-line results from Aerovant Phase 2b clinical trial for eosinophilic asthma

Boosting levels of ABCG1 protein in diabetics will improve insulin production

La Jolla Institute scientist finds protein key to insulin secretion

Report finds racial and ethnic disparities in children's health and health care

Guardian Home Care Holdings, Cardiocom provide home telehealth technology to patients with chronic illnesses

EDEMA4 study results of KALBITOR for treatment of acute attacks of HAE published

Smoke-free laws protect both children and adults from exposure to secondhand smoke

Study sheds light on how IMT improves performance in endurance sports

Unhealthy diet and lifestyle linked to childhood asthma - study

FDA issues letter directing GSK to revise product labeling for Serevent and Advair

Top physicians offer health advice to help people survive during summer

Entelos' T1D PhysioLab platform published in Clinical and Experimental Immunology

Centocor Ortho Biotech acquires RespiVert

Allergic reactions prevent people with allergic asthma from generating healthy immune response to influenza

One-quarter of all hospital patients experience readmission for same conditions: AHRQ

Weill Cornell Medical College commences construction of 18-story, $650 million Medical Research Building

Amira announces UK patent grant for heteroalkyl antagonists of prostaglandin D2 receptors

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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