Clinical Trial News and Research

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Low-income middle-aged African-American women with hypertension commonly suffer from depression

Low-income middle-aged African-American women with high blood pressure very commonly suffer from depression and should be better screened for this serious mental health condition, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Feb 2021

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

11 Feb 2021

HIV self-testing increases testing uptake and frequency in trans people

HIV self-testing could reduce the time between HIV infection and HIV diagnosis amongst trans people when compared to standard testing services, suggests new research in EClinicalMedicine.

11 Feb 2021

New study shares preliminary data on Pfizer vaccine’s effectiveness in Israel

Researchers have shown that by mid-January, the number of COVID-19 cases and hospitalizations in Israel began to decline with a larger and earlier decrease among older people.

11 Feb 2021

Scientists avert drug resistance in subtype of brain tumors

In far too many cases over the years, scientists have discovered promising new cancer treatments, only to report later that the tumor cells found ways to become resistant. These disappointing results have made overcoming drug resistance a major goal in cancer research.

11 Feb 2021

Minimally-invasive deep aging clocks could improve response to COVID-19 vaccine

Deep Longevity, a fully-owned subsidiary of Regent Pacific (SEHK:0575.HK), specializing in the development and the application of next-generation artificial intelligence (AI) for aging and longevity research, today announced the publication of an article in Lancet Healthy Longevity titled "The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19".

11 Feb 2021

Virtual reality app can help reduce fear of heights

Researchers from the University of Basel have developed a virtual reality app for smartphones to reduce fear of heights.

10 Feb 2021

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

The University of Texas MD Anderson Cancer Center and Mirati Therapeutics, Inc. today announced a strategic research and development collaboration to expand the evaluation of Mirati's two investigational small molecules, potent and selective KRAS inhibitors - adagrasib (MRTX849), a G12C inhibitor in clinical development, and MRTX1133, a G12D inhibitor in preclinical development, as monotherapy and in combination with other agents - which target two of the most frequent KRAS mutations in cancer.

10 Feb 2021

Lundquist Institute receives grant to evaluate safety, efficacy of compound for treating psychological distress

The Lundquist Institute has received a $1.75 million grant from the Steven & Alexandra Cohen Foundation to fund a multi-site clinical trial to evaluate the efficacy and safety of the compound psilocybin in individuals with severe psychological distress associated with a terminal medical illness.

10 Feb 2021

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for bamlanivimab and etesevimab administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) who test positive for SARS-CoV-2 and who are at high risk for progressing to severe COVID-19.

10 Feb 2021

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

McMaster University researchers are leading a large international study to test drugs to treat COVID-19 patients.

9 Feb 2021

New combination treatment approach improves overall survival in mice with glioblastoma

In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma.

9 Feb 2021

Older patients often do not receive optimal therapy for esophageal cancers due to perceived risks

Elderly patients (70 years and over) with locally advanced esophageal (E) and esophagogastric junction (EGJ) cancer (located in the stomach and esophagus) should be considered for optimal therapy that has the potential to cure.

9 Feb 2021

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

A new animal study, published in the Journal of Clinical Biochemistry and Nutrition, suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with Helicobacter pylori (H. pylori) infection, a widespread bacterial infection that affects more than half of the world's population.

9 Feb 2021

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

An interview with Madeleine Swortwood of Sam Houston State University, on the symposia she will give at Pittcon 2022 about the analytical challenges of cannabis and its impacts on driving and public health.

From Pittcon 9 Feb 2021

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

A clinical study led by Dr. Jordan Feld, a liver specialist at Toronto Centre for Liver Disease, University Health Network (UHN), showed an experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients – patients who do not need to be hospitalized.

8 Feb 2021

Anticancer drug may reduce mortality and speed up recovery for severe COVID-19 patients

Treating severe COVID-19 patients with the anticancer drug bevacizumab may reduce mortality and speed up recovery, according to a small clinical study in Italy and China that was led by researchers at Karolinska Institutet in Sweden between February and April 2020.

6 Feb 2021

$FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma$

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Today, the U.S. Food and Drug Administration approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients with certain types of large B-cell lymphoma who have not responded to, or who have relapsed after, at least two other types of systemic treatment.

5 Feb 2021

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

Researchers at UPMC Hillman Cancer Center and the National Cancer Institute demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy - which has a failure rate of 40% for this type of cancer - into patients who do.

5 Feb 2021

Clinical Trial News and Research

Low-income middle-aged African-American women with hypertension commonly suffer from depression

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

HIV self-testing increases testing uptake and frequency in trans people

New study shares preliminary data on Pfizer vaccine’s effectiveness in Israel

Scientists avert drug resistance in subtype of brain tumors

Minimally-invasive deep aging clocks could improve response to COVID-19 vaccine

Virtual reality app can help reduce fear of heights

MD Anderson and Mirati Therapeutics collaborate to expand evaluation of potent KRAS inhibitors

Lundquist Institute receives grant to evaluate safety, efficacy of compound for treating psychological distress

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

New study to evaluate the effectiveness of drugs on preventing COVID-19 progression

New combination treatment approach improves overall survival in mice with glioblastoma

Older patients often do not receive optimal therapy for esophageal cancers due to perceived risks

Regular walnut intake may help protect against negative outcomes associated with H. pylori infection

Challenges of Cannabis Analysis and Impacts on Driving and Public Health

A precursor to remdesivir shows therapeutic potential for COVID-19

Experimental antiviral drug can significantly speed up recovery for COVID-19 outpatients

Anticancer drug may reduce mortality and speed up recovery for severe COVID-19 patients

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Fecal transplant overcomes resistance to immunotherapy in melanoma patients

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