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Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

In this interview, News-Medical speaks to Professor Weibke Arlt about her recent research into how the contraceptive pill affects type 2 diabetes in women with PCOS.

22 Nov 2021

A canine coronavirus zoonotic spillover and tropism shift

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21 Nov 2021

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

A new study published in the journal mBio investigates different antibodies from convalescent donors that bind three separate domains of the SARS-CoV-2 spike. The results of this study suggest that the individuals exposed to the SARS-CoV-2 from the first wave have neutralizing antibodies against current variants.

21 Nov 2021

Sheep at low-risk for infection with SARS-CoV-2

A team of scientists from the US has recently evaluated the susceptibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in sheep. The findings reveal that sheep are generally less susceptible to SARS-CoV-2 infection. However, the susceptibility is relatively higher for the alpha variant of the virus. The study is currently available on the bioRxiv preprint server.

21 Nov 2021

Study explores connections between COVID-19 severity and gene expression in immune cells

New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

21 Nov 2021

A trio of proteins found to drive inflammation in psoriasis

About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies - and for many, the relief is temporary.

21 Nov 2021

Naturally occurring phage A1-1 kills dysentery-causing bacteria in sub-Saharan Africa, southern Asia

Phages are viruses that infect bacteria and can also be used to treat human infections. However, as with antibiotics, bacteria can readily evolve resistance to phage attack, highlighting a key limitation to the use of phages as therapeutics.

21 Nov 2021

Scientists unravel near-atomic-scale structure of depression-linked brain receptor

Scientists at Scripps Research, Florida have determined the near-atomic-scale structure of an unusual brain-cell receptor called GPR158, which has been linked to depression and anxiety.

20 Nov 2021

How to achieve fast, accurate and reliable quantitation of AAV serotypes

In this interview, News-Medical talks to Indrani Chakraborty from GatorBio about how they have achieved accurate and reliable quantitation of AAV serotypes.

From Gator Bio, Inc. 19 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Researchers identified a subset of species in which the threat of spillback infection appears the most significant due to location and increased contact with humans in areas with a high prevalence of SARS-CoV-2.

19 Nov 2021

A nasal COVID vaccine using a weakened influenza vector

The authors of a new study, published on the bioRxiv* preprint server, constructed a COVID-19 nasal vaccine candidate by inserting a gene encoding the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2, named CA4-dNS1-nCoV-RBD (dNS1-RBD) in a live attenuated influenza virus (LAIV) vector.

18 Nov 2021

Severe COVID-19 patients have significantly higher NK and T cell frequency

A new study published in the open-access journal Cells aimed to clarify the role of NK and T cell subsets in SARS-CoV-2 infection in hospitalized COVID-19 patients to unravel their potential association with disease severity.

18 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021