Therapeutics News and Research

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Improving cancer therapies by exploiting drug resistance in cancer

News-Medical talks to Professor David Thomas about his recent research identifying the mechanisms behind cancer cells developing resistance to drugs.

23 Jun 2020

SARS-CoV-2 induces broad T cell response in recovering patients

A new study published on the preprint server bioRxiv in June 2020 shows that T cell responses in COVID-19 patients are broader and more robust in severe disease and are explicitly directed against spike, memory, and ORF3a proteins.

23 Jun 2020

Organoids can help provide new level of accuracy in prescribing anti-cancer therapies

Precision medicine, using the power of the human genome to diagnose and treat patients, is about to get even more precise.

22 Jun 2020

Manipulating macrophages could be a viable strategy for treating cancer

Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell.

22 Jun 2020

Researchers identify mouse model that mimics HFpEF syndrome in humans

A receptor that plays an essential role in safely clearing chronic unresolved cardiac inflammation may offer new targets for treating an increasing type of heart failure associated with age-related obesity, suggests a preclinical study led by researchers at the University of South Florida Health Heart Institute, Morsani College of Medicine.

22 Jun 2020

Researchers show new way to help the body efficiently repair injuries

By softening a cell's nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believe they've demonstrated a new way to help the body efficiently repair injuries.

22 Jun 2020

Scientists show how harmless adenovirus disrupts the heart's electrical signaling

Adenovirus, which typically can cause a common cold, has a far more dangerous impact if it reaches the heart.

22 Jun 2020

Human trials to commence using SARS-CoV-2 antibodies from cow's blood

The coronavirus pandemic has sparked a sense of urgency as it actively spreads across the globe. The number of reported cases has now surpassed 8.46 million people, with a death toll of more than 453,000. Scientists and pharmaceutical companies are racing to develop an effective treatment and vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Jun 2020

Blood types and COVID-19 risk confirmed

Blood type may play a pivotal role in driving disease severity among coronavirus disease (COVID-19) patients. Genetic analysis of COVID-19 patients has shown that people with blood type O seemed to be protected against severe disease. In contrast, those with blood type A may experience complications tied to the viral infection.

18 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

By performing a genome-wide CRISPR screen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), U.S. researchers identified novel proviral genes and pathways, and highlighted host genes that may regulate coronavirus disease (COVID-19) pathogenesis, as well as revealing potential targets for novel treatment approaches. Their findings are currently available on the bioRxiv* preprint server.

18 Jun 2020

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug may be repurposed as a treatment for resurgent or chemotherapy-resistant leukemia.

18 Jun 2020

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Lonza and the Swedish company CELLINK have partnered to offer a comprehensive 3-dimensional bioprinting solution designed to optimize and increase access to complete 3D cell culture workflows.

18 Jun 2020

Impact Biomedical's COVID-19 research published in peer-reviewed scientific journal

SGX-listed Singapore eDevelopment Limited's wholly owned subsidiary Impact Biomedical Inc. announced today that their COVID-19 research with Global Research and Discovery Group Sciences, conducted in collaboration with Harvard Medical School and Vilotos Pharmaceutical, Inc., was published in the peer-reviewed scientific journal Molecules on June 11, 2020.

18 Jun 2020

Thin adhesive film upgrades consumer smartwatch into a powerful health-monitoring system

UCLA engineers have designed a thin adhesive film that could upgrade a consumer smartwatch into a powerful health-monitoring system.

18 Jun 2020

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

Now, a team of scientists at Scripps Research has developed new molecules that can restore the balance in gut bacteria in the intestines and as a result, lowers cholesterol levels and reverses the narrowing of the arteries, also known as atherosclerosis.

18 Jun 2020

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

Critical Path Institute announced today that its Transplant Therapeutics Consortium has received a positive response to its Letter of Intent from the U.S. Food and Drug Administration detailing the decision to accept the Composite Biomarker Panel (iBox Scoring System) into the Center for Drug Evaluation and Research (CDER) Biomarker Qualification Program.

17 Jun 2020

NAU research centers receive grants from Flinn Foundation to support COVID-19 response

Scientists at two Northern Arizona University research centers--the Pathogen and Microbiome Institute and the Center for Health Equity Research--recently received grants totaling $175,000 from the Flinn Foundation in support of projects directed at responding to the COVID-19 threat.

17 Jun 2020

Researchers call for caution of using CAR-T immunotherapy against AML

Acute myeloid leukemia is a hematological malignancy which incidence increases with age, that is biologically, phenotypically, and genetically very heterogeneous.

17 Jun 2020

Researchers solve structure of key enzyme critical for biofilm formation in fungal pathogen

Aspergillus fumigatus is a species of fungus that can cause serious illnesses in immunocompromised individuals such as those who are undergoing transplantation or cancer chemotherapy.

17 Jun 2020

Therapeutics News and Research

Improving cancer therapies by exploiting drug resistance in cancer

SARS-CoV-2 induces broad T cell response in recovering patients

Organoids can help provide new level of accuracy in prescribing anti-cancer therapies

Manipulating macrophages could be a viable strategy for treating cancer

Researchers identify mouse model that mimics HFpEF syndrome in humans

Researchers show new way to help the body efficiently repair injuries

Scientists show how harmless adenovirus disrupts the heart's electrical signaling

Human trials to commence using SARS-CoV-2 antibodies from cow's blood

Blood types and COVID-19 risk confirmed

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

Overcoming leukemia treatment resistance with nanoparticle drug delivery system

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Impact Biomedical's COVID-19 research published in peer-reviewed scientific journal

Thin adhesive film upgrades consumer smartwatch into a powerful health-monitoring system

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

C-Path's Transplant Therapeutics Consortium receives positive FDA response for its Letter of Intent

NAU research centers receive grants from Flinn Foundation to support COVID-19 response

Researchers call for caution of using CAR-T immunotherapy against AML

Researchers solve structure of key enzyme critical for biofilm formation in fungal pathogen

Advancing therapeutic biopolymer development eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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