Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Study: Green tea extract with polyethylene glycol could help control body weight gain

Evidence has shown that green tea extract may be an effective herbal remedy useful for weight control and helping to regulate glucose in type 2 diabetes.

30 Apr 2013

Merck, Pfizer sign collaboration agreement for development and commercialization of ertugliflozin

Merck & Co., Inc., known as MSD outside the United States and Canada, and Pfizer Inc. today announced that they have entered into a worldwide (except Japan) collaboration agreement for the development and commercialization of Pfizer's ertugliflozin (PF-04971729), an investigational oral sodium glucose cotransporter (SGLT2) inhibitor being evaluated for the treatment of type 2 diabetes.

From Pfizer, Inc. 30 Apr 2013

Oramed to report results of T1DM oral insulin formulation at Diabetes Summit 2013

Oramed Pharmaceuticals Inc., a developer of oral delivery systems of drugs currently administered by injection, announced today that its abstract, entitled "Oral insulin capsules toward management of Type 1 diabetes mellitus," will be presented at the Global Technology Community Diabetes Summit 2013.

29 Apr 2013

Study may pave way for new strategies to fight cancer cells

For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells.

29 Apr 2013

Intermittent fasting: A path to weight loss and improved cardiovascular risk

Intermittent fasting is all the rage, but scientific evidence showing how such regimes affect human health is not always clear cut. Now a scientific review in the British Journal of Diabetes and Vascular Disease published by SAGE, suggests that fasting diets may help those with diabetes and cardiovascular disease, alongside established weight loss claims.

29 Apr 2013

Metabolic risk factors in overweight children linked with mild artery wall stiffness

Metabolic disorders, such as excess abdominal fat, raised blood pressure, higher levels of insulin, glucose and triglycerides and lower levels of the beneficial HDL cholesterol can be found in children as young as 6 to 8 years of age, according to a study carried out at the University of Eastern Finland.

26 Apr 2013

GI nematode infections combat obesity and improve related metabolic disorders

Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders.

26 Apr 2013

Serum C-peptide levels predict cardiovascular death risk

Levels of C-peptide predict the risk for death from cardiovascular disease in nondiabetic adults, show data from the US National Health and Nutrition Examination Survey.

25 Apr 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

Findings open new possibilities for research, testing treatments to combat obesity

Joslin scientists report significant findings about the location, genetic expression and function of human brown adipose tissue and the generation of new BAT cells.

23 Apr 2013

Eli Lilly reports positive results from Phase III AWARD trials of type 2 diabetes drug, dulaglutide

Eli Lilly and Company today announced positive top-line results of two additional Phase III AWARD trials for dulaglutide, an investigational, long-acting glucagon-like peptide 1 (GLP-1) receptor agonist being studied as a once-weekly treatment for type 2 diabetes.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

Obesity epidemic in the Asia Pacific region: an interview with Prof Drexel, European Society of Cardiology

The prevalence of obesity is about 20 % in Australia, 17 % in Japan, but only 3 – 4 % in China. Thus, Asia Pacific is a very heterogeneous region.

15 Apr 2013

Protein EPAC2 plays major role in development of type 2 diabetes

A team of researchers at the Johns Hopkins Children's Center has found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly 26 million people in the United States alone and counts as one of the leading causes of heart disease, stroke and kidney, eye and nerve damage.

12 Apr 2013

CCS Medical named winner in national Competitive Bidding Program of CMS

CCS Medical, a leading provider of home delivery medical equipment and supplies, announced today that it has been named a winner in the national Competitive Bidding Program of the Centers for Medicare & Medicaid Services.

12 Apr 2013

Discovery suggests new therapeutic target for treating dysfunctional beta cells, type 2 diabetes

Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release insulin.

12 Apr 2013

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes.

11 Apr 2013

Non-invasive battery recharger system for electronic implants

Ant-nio Abreu, a Sustainable Energy Systems PhD Student under the MIT Portugal Program, currently developing research work at LNEG (Laborat-rio Nacional de Energia e Geologia I.P.) has developed a non-invasive battery recharger system for electronic implants that allows a longer life for the internal implantable devices in the human body such as, pacemakers, defibrillators, electric heart, delaying considerable the usual customary surgery intervention for replacement.

10 Apr 2013

Mother's stress associated with development of pathologies related with obesity

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated with the development of pathologies related with obesity.

10 Apr 2013

Relationship between obesity and PCOS may be exaggerated, say researchers

The relationship between obesity and polycystic ovary syndrome may be exaggerated, likely because the women who actively seek care for the condition tend to be heavier than those identified through screening of the general population, researchers report.

9 Apr 2013

Insulin News and Research

Further Reading

Study: Green tea extract with polyethylene glycol could help control body weight gain

Merck, Pfizer sign collaboration agreement for development and commercialization of ertugliflozin

Oramed to report results of T1DM oral insulin formulation at Diabetes Summit 2013

Study may pave way for new strategies to fight cancer cells

Intermittent fasting: A path to weight loss and improved cardiovascular risk

Metabolic risk factors in overweight children linked with mild artery wall stiffness

GI nematode infections combat obesity and improve related metabolic disorders

Serum C-peptide levels predict cardiovascular death risk

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

Findings open new possibilities for research, testing treatments to combat obesity

Eli Lilly reports positive results from Phase III AWARD trials of type 2 diabetes drug, dulaglutide

UTMB researchers identify protein that can interfere with the brain's response to leptin

Obesity epidemic in the Asia Pacific region: an interview with Prof Drexel, European Society of Cardiology

Protein EPAC2 plays major role in development of type 2 diabetes

CCS Medical named winner in national Competitive Bidding Program of CMS

Discovery suggests new therapeutic target for treating dysfunctional beta cells, type 2 diabetes

Coenzyme Q10 offsets cellular changes that are linked to side-effect of some statin drugs: Study

Non-invasive battery recharger system for electronic implants

Mother's stress associated with development of pathologies related with obesity

Relationship between obesity and PCOS may be exaggerated, say researchers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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