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Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads to blocked arteries, by looking at how cells in our blood vessels change their function.

1 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Repair defect in neurons hints at possible therapy for preventing ALS

Houston Methodist researchers have discovered a repair defect in nerve cells that send messages to the brain, opening the door to a possible therapy for preventing or slowing down ALS.

1 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

UA scientists aim to identify drug targets for rare pediatric cancer

Rhabdomyosarcoma is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes).

1 Nov 2018

Toxic protein assemblies found to play beneficial role in muscle generation

Toxic protein assemblies, or "amyloids," long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers have found.

1 Nov 2018

Researchers discover biomarker for most common type of heart failure

A team led by a Cedars-Sinai physician-scientist has discovered a biomarker--a protein found in the blood--for the most common type of heart failure, a new study published today in JAMA Cardiology shows.

1 Nov 2018

Researchers discover how protein pair regulates cellular calcium signals

All mammalian cells need a ready supply of calcium ions to execute functions as diverse as neurotransmission, muscle contraction, hormone release, or immune responses. So fundamental is this requirement that cells protect themselves from disaster by storing calcium in a network of intracellular cisterns called the endoplasmic reticulum, or ER.

31 Oct 2018

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine.

31 Oct 2018

Using genome editing to prevent sudden cardiac death

Each year, at least 3 million people worldwide die of sudden cardiac death. In the U.S., this number reaches up to 450,000 people.

30 Oct 2018

Individual heart cells respond differently to high blood pressure

A team of cardiologists have found that single cells within the heart are affected by high blood pressure in different ways. Some adapt, whilst others fail.

30 Oct 2018

Individual cells within the same heart cope differently with high blood pressure, study shows

Individual cells within the same heart cope differently with high blood pressure, according to a study in human cells and mice by a team of cardiologists and computational biologists at the University of Tokyo.

30 Oct 2018

Cephalopods could become new source of protein for people around the world

Among chefs and researchers in gastronomy there is a growing interest in exploring local waters in order to use resources in a more diverse and sustainable manner, including using the cephalopod population as a counterweight to the dwindling fishing of bonefish, as well as an interest in finding new sources of protein that can replace meat from land animals.

30 Oct 2018

Elite coaches and athletes use Humon's muscle oxygen monitor to improve performance

Humon today revealed its latest list of elite coaches and athletes endorsing the company's muscle oxygen monitor.

30 Oct 2018

Researchers develop new app that reminds users to relax and prevent stress

Whether at work or at leisure - more and more people are feeling stressed. This makes it all the more important to learn to consciously relax in order to get stress under control.

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S announced study results on the safety and efficacy of brexpiprazole in the treatment of patients with schizophrenia experiencing severe psychotic symptoms during an acute episode. The data will be presented at the upcoming Psych Congress, held in Orlando from October 25-28, 2018.

26 Oct 2018

New discovery may unlock development of next-generation sleeping pill

Insomnia is one of the major sleep problems with an estimated prevalence of 10% to 15% in the general population and 30% to 60% in the older population. Moreover, insomnia frequently co-occurs with a wide range of psychiatric disorders, including depression and anorexia.

26 Oct 2018

Good mental ability and grip strength may prevent or delay disability in older adults

As we age, we may develop certain disabilities that make it difficult to walk, climb, balance, or maintain our fine motor skills.

25 Oct 2018

Protein-filled snack before bed appears to have positive effect on health

Eager to eat a snack before bedtime? A protein-filled snack like cottage cheese is the way to go, say Florida State University researchers.

25 Oct 2018

Muscle News and Research

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Repair defect in neurons hints at possible therapy for preventing ALS

CNIO researchers link MASTL protein to origin of thrombocytopenia

UA scientists aim to identify drug targets for rare pediatric cancer

Toxic protein assemblies found to play beneficial role in muscle generation

Researchers discover biomarker for most common type of heart failure

Researchers discover how protein pair regulates cellular calcium signals

CRISPR genome editing has foreseeable implications for plastic and reconstructive surgery

Using genome editing to prevent sudden cardiac death

Individual heart cells respond differently to high blood pressure

Individual cells within the same heart cope differently with high blood pressure, study shows

Cephalopods could become new source of protein for people around the world

Elite coaches and athletes use Humon's muscle oxygen monitor to improve performance

Researchers develop new app that reminds users to relax and prevent stress

Getting right level of leptin may help protect cardiovascular health

Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

New discovery may unlock development of next-generation sleeping pill

Good mental ability and grip strength may prevent or delay disability in older adults

Protein-filled snack before bed appears to have positive effect on health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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