Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Researchers at the University of Michigan School of Kinesiology have received a $1 million grant to study how exercise and other therapies might work differently in lean and obese individuals.

28 Feb 2013

Study indicates how gastric bypass reverses diabetes

In a substudy of the STAMPEDE trial (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently), Cleveland Clinic researchers have found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function in moderately obese patients with uncontrolled type 2 diabetes.

28 Feb 2013

Protamine–heparin complex antibodies raise concerns

Almost a third of patients treated with protamine for heparin reversal during cardiopulmonary bypass develop antibodies to circulating protamine–heparin complexes, study findings suggest.

25 Feb 2013

GLP-1 may increase risk of hospitalization for people with acute pancreatitis

People who take the newest class of diabetes drugs to control blood sugar are twice as likely as those on other forms of sugar-control medication to be hospitalized with pancreatitis, Johns Hopkins researchers report.

25 Feb 2013

Disruption in the body's circadian rhythm can increase risk of diabetes, heart disease

Disruption in the body's circadian rhythm can lead not only to obesity, but can also increase the risk of diabetes and heart disease.

22 Feb 2013

Study describes pharmacological action of TZDs directly on pancreas

A scientific study published on the journal Diabetes, edited by the American Diabetes Association, describes for the first time the pharmacological action of thiazolidinediones (TZDs) —anti-diabetic drugs— directly on pancreas, the organ which produces insulin.

18 Feb 2013

Artificial pancreas improves on insulin pump therapy in Type 1 diabetes

The dual-hormone closed-loop delivery system, a type of artificial pancreas, could offer significant advantages over conventional insulin pump therapy in Type 1 diabetes patients, report researchers.

15 Feb 2013

Oramed to submit new oral insulin IND with FDA

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has been in communication with the U.S. Food and Drug Administration (FDA) regarding its Investigational New Drug (IND) application for oral insulin.

15 Feb 2013

Cardinal Health announces plans to acquire AssuraMed

Cardinal Health today announced plans to acquire privately held AssuraMed, a leading provider of medical supplies to patients in the home, for $2.07 billion, or $1.94 billion, net of the present value of tax benefits.

15 Feb 2013

Excess weight gain, obesity during pregnancy may increase risk of macrosomia

Epidemiologists at Boston University School of Public Health (BUSPH) have found that pre-pregnancy obesity and excess weight gain during pregnancy in African-American women are associated with an increased risk of giving birth to an abnormally large baby.

13 Feb 2013

Study finds reduced insulin effectiveness, high blood pressure in first-born children

Long a source of sibling rivalry, birth order may raise the risk of first-born children developing diabetes or high blood pressure, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

12 Feb 2013

MannKind fourth quarter total operating expenses increase to $33.5 million

MannKind Corporation today reported financial results for the fourth quarter and year ended December 31, 2012.

12 Feb 2013

Long-acting reversible contraception with progestin may increase risk of type 2 diabetes in women

A first-of-its-kind study by researchers at the Keck School of Medicine of the University of Southern California (USC) indicates that healthy, obese, reproductive-age women who use long-acting reversible contraception (LARC) containing the hormone progestin have a slightly increased risk for developing type 2 diabetes when compared to those who use non-hormonal contraception.

11 Feb 2013

Virginia Tech researchers reveal how 'bad' gut bacteria may help control diabetes

A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists at the Virginia Bioinformatics Institute of Virginia Tech.

10 Feb 2013

Single gene therapy session can cure diabetes

Researchers from the Universitat Aut-noma de Barcelona (UAB), led by F-tima Bosch, have shown for the first time that it is possible to cure diabetes in large animals with a single session of gene therapy. As published this week in Diabetes, the principal journal for research on the disease, after a single gene therapy session, the dogs recover their health and no longer show symptoms of the disease.

10 Feb 2013

Academic medical centers play an integral role in developing new treatments and cures

As an internationally recognized researcher into aging and dementia, Suzanne Craft is keenly aware of the importance of volunteers in clinical studies.

9 Feb 2013

Tumor necrosis factor receptor 2 involved in renal decline in diabetes

Researchers have found that circulating levels of tumor necrosis factor receptor 2 are independently associated with the development of chronic kidney disease in nonobese Japanese patients with Type 2 diabetes.

8 Feb 2013

Study finds two biomarkers of acute kidney injury

Acute kidney injury strikes large numbers of hospitalized patients, including those with no prior kidney-related illness, and is one of the most costly and deadly conditions affecting critically ill patients.

7 Feb 2013

Paternal obesity may alter genetic mechanisms in next generations

A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.

6 Feb 2013

U.S. adults with diabetes report increased satisfaction with Roche's ACCU-CHEK products

Adults living with diabetes in the United States reported highest satisfaction using Roche Diabetes Care's ACCU-CHEK products compared with other blood glucose meter manufacturers, according to the inaugural J.D. Power and Associates 2012 Blood Glucose Meter Satisfaction Study.

6 Feb 2013