immunity News and Research

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4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The Journal of Nuclear Medicine.

8 Feb 2021

Moderna's COVID-19 vaccine effective against emerging variants

Researchers have conducted a study showing that the Moderna mRNA-1273 vaccine effectively protects against recently emerged variants of SARS-CoV-2 – the agent that causes COVID-19.

8 Feb 2021

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Researchers at the University of Nebraska Medical Center have developed a bacterial strategy for the expression and purification of the SARS-CoV-2 spike protein receptor-binding domain (RBD).

8 Feb 2021

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

A team of researchers recently examined the SARS-CoV-2 transcriptome and the dynamics of the S gene furin cleavage site in primary human airway epithelia.

8 Feb 2021

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

A new study describes the use of DARPin (designed ankyrin repeat proteins) therapeutic agents, each of which contains three different DARPin domains within the same molecule.

8 Feb 2021

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

A recent study describes the experimental selection of SARS-CoV-2 mutants associated with resistance to antibodies, with important implications for vaccine development and therapeutic antibody use.

8 Feb 2021

Why the U.S. is underestimating Covid reinfection

Kaitlyn Romoser first caught Covid-19 in March, likely on a trip to Denmark and Sweden, just as the scope of the pandemic was becoming clear. Romoser, who is 23 and a laboratory researcher in College Station, Texas, tested positive and had a few days of mild, coldlike symptoms.

8 Feb 2021

Healthy people volunteering to be infected with SARS-CoV-2 should be paid, experts suggest

Multidisciplinary team of international experts suggests participants should receive a "substantial" amount, be paid ethically.

7 Feb 2021

Gut fungi teach the immune system how to respond to their dangerous relatives

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections.

7 Feb 2021

Novel immunotherapy approach to revert the main hallmarks of cat allergy

Researchers from the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) brought forward the potential of high doses of a specific adjuvant molecule, namely CpG oligonucleotide, in successfully modulating the immune system's allergic response to the main cat allergen Fel d 1, thereby inducing a tolerance-promoting reaction and reverting the main hallmarks of cat allergy.

5 Feb 2021

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

Researchers at the University of Pittsburgh School of Pharmacy and West Health Policy Center found that in many parts of the country, Black people are less likely than white people to live near a pharmacy, clinic, hospital or health center that can administer COVID-19 vaccines.

5 Feb 2021

Study indicates that 2019-2020 flu season was driven by a new, more transmissible strain

The 2019-2020 flu season in the U.S. was unusual in a number of ways. Cases picked up in August rather than the more typical fall and early winter months, and it hit children particularly hard. It was also dominated early on by a Type B influenza virus instead of one of the much more common Type A viruses like H1N1 or H3N2.

5 Feb 2021

Zinc supplements can improve infertility issues during COVID-19 pandemic

Wayne State University School of Medicine researchers have reported that zinc supplements for men and women attempting to conceive either naturally or through assisted reproduction during the COVID-19 pandemic may prevent mitochondrial damage in young egg and sperm cells, as well as enhance immunity against the virus.

5 Feb 2021

Study: COVID-19 cases in India are nearly 95 times greater than reported

A new study, led by professors at the University of Chicago and Duke University, found that COVID-19 cases in the southern state of Karnataka, India, are nearly 95 times greater than reported.

5 Feb 2021

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system. Both mast cells and neutrophils are white blood cells and are critical for the body's immune defense.

5 Feb 2021

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.

4 Feb 2021

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

A new preprint posted to the bioRxiv server demonstrates that similar mucins and mucin-like proteins cannot only suppress HIV-1 infectivity via blockage of viral attachment to the host cells but can block infection by multiple enveloped viruses.

4 Feb 2021

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Among these is the B.1.1.7 SARS-CoV-2 variant, with its characteristic N501Y mutation. A new preprint on the bioRxiv server reports the impact of this mutation on CD4 T cell responses, including antigen presentation on cells expressing Major Histocompatibility Complex (MHC) class II molecules.

4 Feb 2021

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

In the canton of Bern, only 14% of the adult population were infected with the coronavirus and developed antibodies against SARS-CoV-2.

4 Feb 2021

immunity News and Research

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

Moderna's COVID-19 vaccine effective against emerging variants

Scientists produce active antigen in bacteria to help combat SARS-CoV-2

Furin cleavage SARS-CoV-2 spike deletions mostly suppressed within infected airway epithelium, says study

Bioengineered ankyrin compounds show high in vitro activity against SARS-CoV-2 mutants

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

Why the U.S. is underestimating Covid reinfection

Healthy people volunteering to be infected with SARS-CoV-2 should be paid, experts suggest

Gut fungi teach the immune system how to respond to their dangerous relatives

Novel immunotherapy approach to revert the main hallmarks of cat allergy

Study: Black people are less likely to live near hospitals that administer COVID-19 vaccines

Study indicates that 2019-2020 flu season was driven by a new, more transmissible strain

Zinc supplements can improve infertility issues during COVID-19 pandemic

Study: COVID-19 cases in India are nearly 95 times greater than reported

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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