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PhoreMost demonstrates new approach to rationalize molecular glue drug discovery

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced the publication of a study demonstrating the capabilities of its high-throughput GlueSEEKER platform to accelerate the design and development of novel molecular glue degraders.

22 Jul 2025

PFAS exposure may increase the risk of developing type 2 diabetes

Exposure to a class of synthetic chemicals known as per- and polyfluoroalkyl substances (PFAS)-often called "forever chemicals"-may increase the risk of developing type 2 diabetes, according to a new study led by Mount Sinai researchers.

22 Jul 2025

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

Gene editing in the brain offers hope for ultra-rare neurological disease

Scientists have corrected gene mutations in mice causing an ultra-rare disease by editing DNA directly in the brain with a single injection, a feat with profound implications for patients with neurological diseases.

21 Jul 2025

Fluorescent bacteria enable real-time tumor visualization during surgery

Accurate removal of tumors is the most critical aspect of cancer surgery, yet it remains a significant challenge in clinical practice.

21 Jul 2025

AI reshapes ARDS care by predicting risk, guiding ventilation, and personalizing treatment

Artificial intelligence and machine learning are transforming acute respiratory distress syndrome (ARDS) management, enabling earlier detection, precision risk stratification, and tailored therapies. Emerging AI techniques promise to improve outcomes, but real-world clinical validation and integration remain critical challenges.

21 Jul 2025

Research highlights guselkumab's impact on Crohn's endoscopic healing

In a major advance for patients with Crohn's disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief.

18 Jul 2025

Measles outbreaks surge worldwide, driven by declining immunization coverage

The Global Virus Network (GVN), a coalition of leading human and animal virologists from 80+ Centers of Excellence and Affiliates in more than 40 countries, is sounding the alarm over a sharp resurgence of measles cases in the United States and globally.

17 Jul 2025

Robotic-assisted neuroendovascular aneurysm embolization shows promising 6-month results

The six-month follow-up results from the pioneering trial of robotic-assisted neuroendovascular aneurysm embolization using the CorPath GRX system were presented today by Vitor Pereira, MD on behalf of the investigators at the Society of NeuroInterventional Surgery's (SNIS) 22nd Annual Meeting.

17 Jul 2025

Prestigious Stephenson Scholar Grants support cutting-edge pancreatic cancer studies

The Stephenson Global Pancreatic Cancer Research Institute and its partner City of Hope, one of the country's largest and most advanced cancer research and treatment organizations, today announced the six inaugural recipients of the prestigious Stephenson Scholar Grants, awarding $5.25 million to support high-impact research aimed at transforming the understanding, early detection and treatment of pancreatic cancer.

16 Jul 2025

Van Andel Institute scientists develop improved technique to profile DNA methylation in single cells

Van Andel Institute scientists have developed an improved technique to comprehensively profile DNA methylation in single cells, an advance that will help researchers better study the role of epigenetics in cancer and other diseases.

16 Jul 2025

FAU neuroscientist receives NIH grant to study amphetamine effects on the brain

Lucia Carvelli, Ph.D., associate professor of neuroscience at Florida Atlantic University's Harriet L. Wilkes Honors College and a member of the FAU Stiles-Nicholson Brain Institute, has received a $571,675 grant from the National Institutes of Health to advance critical research into how amphetamines affect brain function.

15 Jul 2025

Elegen and Nutcracker Therapeutics to pilot first fully cell-free manufacturing process for RNA-based personalized cancer therapeutics

Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot program to demonstrate the industry's first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer therapeutics (PCTs).

From Elegen Corporation 15 Jul 2025

New cellular entry pathway improves gene therapy outcomes

Scientists from the Centenary Institute and the University of Sydney have made a landmark discovery that could lead to safer and more effective gene therapies for a range of serious genetic disorders including Duchenne muscular dystrophy, Pompe disease and hemophilia.

15 Jul 2025

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Researchers engineered a nanobody-conjugated liposome (A5-LNP-DOX) that targets CD155 and delivers doxorubicin directly to lung adenocarcinoma cells, dramatically suppressing tumor growth in preclinical models. This approach not only inhibited cancer cell migration and invasion but also showed strong potential for safer, more precise lung cancer therapy.

14 Jul 2025

Next Generation News and Research

PhoreMost demonstrates new approach to rationalize molecular glue drug discovery

PFAS exposure may increase the risk of developing type 2 diabetes

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Gene editing in the brain offers hope for ultra-rare neurological disease

Fluorescent bacteria enable real-time tumor visualization during surgery

AI reshapes ARDS care by predicting risk, guiding ventilation, and personalizing treatment

Research highlights guselkumab's impact on Crohn's endoscopic healing

Measles outbreaks surge worldwide, driven by declining immunization coverage

Robotic-assisted neuroendovascular aneurysm embolization shows promising 6-month results

Prestigious Stephenson Scholar Grants support cutting-edge pancreatic cancer studies

Van Andel Institute scientists develop improved technique to profile DNA methylation in single cells

FAU neuroscientist receives NIH grant to study amphetamine effects on the brain

Elegen and Nutcracker Therapeutics to pilot first fully cell-free manufacturing process for RNA-based personalized cancer therapeutics

New cellular entry pathway improves gene therapy outcomes

New nanobody-liposome combo stops lung cancer growth and delivers targeted chemotherapy

Early-career physician-scientists receive major support from Damon Runyon Cancer Research Foundation

Sino Biological sets new industry standard with ProPure™ endotoxin-free proteins made in the USA

EAGLE model predicts key lung cancer mutations from routine biopsy

New microchip tracks antibody-virus interactions from a single drop of blood

Prefrontal cortex RNA drives female-specific brain resilience to depression

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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