Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead.

26 Sep 2025

Tumor cells adapt and thrive in damaged parts of the pancreas

Pancreatic cancer is one of the most aggressive cancer types. A new study from Karolinska Institutet, in collaboration with the Department of Pathology at Karolinska University Hospital, shows that tumor cells grow not only in the connective tissue-rich environment typical of the disease, but also in damaged parts of the pancreas where normal tissue is altered.

26 Sep 2025

Calcium-induced release identified as key driver of dangerous muscle disorders

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

25 Sep 2025

Big loopholes in hospital charity care programs mean patients still get stuck with the tab

Quinn Cochran-Zipp went to the emergency room three times with severe abdominal pain before doctors figured out she had early-stage cancer in the germ cells of her right ovary.

25 Sep 2025

Influenza infection in pregnant mice linked to fetal brain exposure

A new study from the University of Illinois Urbana-Champaign shows, for the first time, that severe flu infection in pregnant mice leads to a breakdown in placental and brain barriers, leading to the accumulation of potentially harmful molecules in the fetal brain.

24 Sep 2025

University of Utah launches landmark study linking blood pressure and brain health

In six massive laboratory freezers at the University of Utah, nearly 40,000 blood samples wait in frozen stasis.

24 Sep 2025

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.

24 Sep 2025

Review shows lecanemab and donanemab slow decline and explains who should get them

The Lancet review synthesises evidence on anti beta amyloid monoclonal antibodies and the wider Alzheimer’s care pathway, weighing efficacy, safety, economics, and health system readiness across disease, patient, and population perspectives.

24 Sep 2025

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

24 Sep 2025

How food choices and cooking methods drive brain inflammation and disease

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

24 Sep 2025

New diagnostic methods and treatments needed to fight against Alzheimer's disease

The diagnosis and medical treatment of Alzheimer's disease, a condition that according to leading researchers in the field should be treated, has now advanced significantly.

24 Sep 2025

UC Riverside receives $2 million grant to explore how gut bacteria shape human health

One day, bottles of probiotics might do more than keep you regular -- they could help prevent disease. To get there, a $2 million grant to UC Riverside will explore how gut bacteria shape human health.

23 Sep 2025

Study provides new insights into the mechanisms of fetal membrane healing

When a pregnant woman's water breaks too early, it often leads to preterm birth, with no effective method to prevent or treat it.

23 Sep 2025

UNM researcher develops new model for characterizing different forms of vascular dementia

Vascular dementia - cognitive impairment caused by disease in the brain's small blood vessels - is a widespread problem, but it has not been as thoroughly studied as Alzheimer's disease, in which abnormal plaques and protein tangles are deposited in neural tissue.

19 Sep 2025

New research links postictal symptoms in epilepsy to hidden brain waves

In everyday clinical practice, symptoms are regularly observed after epileptic seizures, known as "post-ictal symptoms", which, in contrast to the usually short duration of seizures, typically last several minutes to hours. Besides symptoms such as impaired speech and language comprehension, a state of disorientation may occur.

19 Sep 2025

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer's disease.

18 Sep 2025

Study identifies microstructural brain changes from heading in amateur soccer athletes

A brain imaging technique developed by Columbia researchers has identified areas in the brain's cerebral cortex-just behind the forehead-that are most damaged by the repetitive impacts from heading a soccer ball.

18 Sep 2025

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative Diseases (DZNE) have identified a neurobiological mechanism that could be responsible for this so-called post-ictal wandering and potentially other postictal symptoms.

18 Sep 2025

New molecule offers a more targeted and potent immunotherapy

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the "do not attack" signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects.

18 Sep 2025

Targeted radiation shows promise for rare solitary fibrous tumors

A novel targeted radiation approach for a rare form of malignant tumor-the solitary fibrous tumor (SFT)-has shown significant success, achieving a near-complete response in three patients.

17 Sep 2025

Pathology News and Research

Further Reading

IGF2BP3 protein drives leukemia growth by linking metabolism and RNA control

Tumor cells adapt and thrive in damaged parts of the pancreas

Calcium-induced release identified as key driver of dangerous muscle disorders

Big loopholes in hospital charity care programs mean patients still get stuck with the tab

Influenza infection in pregnant mice linked to fetal brain exposure

University of Utah launches landmark study linking blood pressure and brain health

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Review shows lecanemab and donanemab slow decline and explains who should get them

Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease

How food choices and cooking methods drive brain inflammation and disease

New diagnostic methods and treatments needed to fight against Alzheimer's disease

UC Riverside receives $2 million grant to explore how gut bacteria shape human health

Study provides new insights into the mechanisms of fetal membrane healing

UNM researcher develops new model for characterizing different forms of vascular dementia

New research links postictal symptoms in epilepsy to hidden brain waves

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Study identifies microstructural brain changes from heading in amateur soccer athletes

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

New molecule offers a more targeted and potent immunotherapy

Targeted radiation shows promise for rare solitary fibrous tumors

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News