Therapeutics News and Research

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Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

Dementia is one of the most debilitating consequences of Parkinson's disease, a progressive neurological condition characterized by tremors, stiffness, slow movement and impaired balance.

6 Feb 2020

Targeting a protein could be key to suppressing breast cancer metastasis

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as heat shock protein 47 (Hsp47) could be key for suppressing breast cancer metastasis.

5 Feb 2020

Smart insulin-delivery patch could monitor and manage glucose levels in people with diabetes

UCLA bioengineers and colleagues at UNC School of Medicine and MIT have further developed a smart insulin-delivery patch that could one day monitor and manage glucose levels in people with diabetes and deliver the necessary insulin dosage.

5 Feb 2020

UH professor examines life cycle of drug-resistant persister cells in recurrent infections

A University of Houston engineering professor is examining the life cycle of stubborn, drug-resistant persister cells in recurrent infections to find a way to destroy them.

4 Feb 2020

Research identifies link between chronic kidney disease and heart failure

People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Now, for the first time in humans, research led by Navkaranbir Bajaj, M.D., of the University of Alabama at Birmingham, has identified a pathological change that appears to link kidney disease to progressive heart disease.

3 Feb 2020

Comparing DNA-repair gene mutations in African American and Caucasian men with prostate cancer

Pathogenic or likely pathogenic alterations in these 14 DNA repair genes were less likely to be detected in African Americans as compared to Caucasians.

3 Feb 2020

New combination treatment could help fight advanced melanoma

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center suggests that using an immunotherapy drug called NKTR-214, also known as bempegaldesleukin, in combination with an infusion of anti-tumor immune cells, or T cells, may produce a stronger immune response that could help fight advanced melanoma.

31 Jan 2020

Advances in tuberculosis research yield immune responses

A new study published in January 2020 in the journal Science Translational Medicine depicts for the first time ever a beautifully detailed map of the way three different species reacts to tuberculosis, based on their genetic and immune differences.

30 Jan 2020

Scientists discover small molecule that may slow or stop Parkinson's disease progression

A collaboration between scientists at Rutgers University and Scripps Research led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

30 Jan 2020

Study maps immune responses to tuberculosis across 3 species

Tuberculosis is one of the world's most vexing public health problems. About 1.5 million people died from this bacterial lung infection in 2018, and the World Health Organization estimates that one-quarter of the world's population -- some 2 billion people, mostly in developing countries -- are infected with the bacteria that causes TB.

30 Jan 2020

Novel inhibitor to fight metastatic prostate cancer shows promise

When prostate cancer spreads it is often a deadly disease, but now a Stony Brook University-led research team believes a new approach that inhibits a specific fatty acid binding protein (FABP) may be the key to halting disease progression.

30 Jan 2020

Pre-existing anticancer drug could help treat common form of heart failure

When it comes to finding new treatments for disease, reinventing the wheel is not always necessary - drugs already in use for other conditions may do the job.

29 Jan 2020

Why new cancer drugs take so long to reach the market

A new analysis of cancer drug development by researchers at the Institute of Cancer Research, London, shows that the more revolutionary a new cancer drug is, the longer it takes to reach patients in the UK’s National Health Service healthcare system. In other words, refinements on earlier drugs or drugs which are more conventional in their effects make it to the marketplace faster

28 Jan 2020

New micro-scale technology holds promise for improved tumor diagnosis

Using a single-needle biopsy and new technology for tumor diagnosis developed by Baylor College of Medicine and the Broad Institute of MIT and Harvard, researchers have been able to provide a more detailed and wider window into cancer biology, tumor type and the mechanisms of response and resistance to therapy than with conventional approaches.

27 Jan 2020

A microdose lithium formulation could halt signs of Alzheimer's pathology

Ncardia and Bluerock Therapeutics announce collaboration agreement and licensing of process development technologies for the manufacture of iPSC-derived cardiomyocytes

Ncardia and BlueRock Therapeutics today announced an agreement covering process development technologies for the manufacture of induced pluripotent stem cell (iPSC)-derived cardiomyocytes.

From Ncardia 23 Jan 2020

Therapeutics News and Research

Scientists identify gene as potential therapeutic target for dementia in people with Parkinson's

Targeting a protein could be key to suppressing breast cancer metastasis

Smart insulin-delivery patch could monitor and manage glucose levels in people with diabetes

UH professor examines life cycle of drug-resistant persister cells in recurrent infections

Research identifies link between chronic kidney disease and heart failure

Comparing DNA-repair gene mutations in African American and Caucasian men with prostate cancer

New combination treatment could help fight advanced melanoma

Advances in tuberculosis research yield immune responses

Scientists discover small molecule that may slow or stop Parkinson's disease progression

Study maps immune responses to tuberculosis across 3 species

Novel inhibitor to fight metastatic prostate cancer shows promise

Pre-existing anticancer drug could help treat common form of heart failure

Why new cancer drugs take so long to reach the market

New micro-scale technology holds promise for improved tumor diagnosis

A microdose lithium formulation could halt signs of Alzheimer's pathology

Scientists discover small molecule that may slow or stop Parkinson's progression

Researchers solve long-standing mystery linked to contraction of heart cells

New study gives hope for potentially developing a cure for HIV

Carterra closes financing round for continued growth of the LSA platform for next generation antibody discovery

Ncardia and Bluerock Therapeutics announce collaboration agreement and licensing of process development technologies for the manufacture of iPSC-derived cardiomyocytes

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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