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Researchers find distinct effects of adversity in the genomes of men than women born preterm

Researchers at McMaster University have found distinct effects of adversity early in life in the genomes of men compared to women who were born extremely preterm.

21 Oct 2020

Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including the respiratory tract, blood vessels and neurons.

21 Oct 2020

Precision epidemiology could help explain variability in COVID-19 symptoms

Researchers from National Taiwan University have presented a multi-omics view of how mutations in angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) affect infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and progression of coronaviruses disease 2019 (COVID-19).

20 Oct 2020

Study helps restore retinal and visual functions of mice models of inherited retinal disease

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

20 Oct 2020

Researchers map the first draft sequence of human proteome

Twenty years after the release of the human genome, the genetic "blueprint" of human life, an international research team, including the University of British Columbia's Chris Overall, has now mapped the first draft sequence of the human proteome.

20 Oct 2020

The connection between severe COVID-19 and white blood cell counts

However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

19 Oct 2020

Cleveland Clinic joins new Center for Integrated Multi-Modal and Multi-Scale Nucleome Research

Cleveland Clinic has been named a participating institution for the newly established Center for Integrated Multi-Modal and Multi-Scale Nucleome Research, made possible by a recently awarded five-year, $6.5 million consortium grant from the National Institutes of Health Common Fund.

19 Oct 2020

Elevated birth weight is linked with atrial fibrillation later in life, shows study

Elevated birth weight is linked with developing atrial fibrillation later in life, according to research presented at the 31st Great Wall International Congress of Cardiology (GW-ICC).

19 Oct 2020

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

Scientists from Oxford University’s Department of Physics have developed an extremely rapid diagnostic test that detects and identifies viruses in less than five minutes.

16 Oct 2020

'Jumping genes' may frequently alter neural function

A new study by neuroscientists at the University of Oxford shows that mobile genetic elements that were active in the genomes of our ancestors could be closely linked to important functions in our brain and might help diversify our behavior, cognition and emotions.

16 Oct 2020

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Synthego, the genome engineering company, has collaborated with The Krogan Lab, a world-renowned scientific research unit at the Quantitative Biosciences Institute (QBI) at the University of California, San Francisco (UCSF), to deliver multiple CRISPR-based engineered cell lines to accelerate the study of potential treatment targets for SARS-CoV-2, the novel coronavirus that causes COVID-19 disease.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

Early trauma leads to changes in blood metabolites, study finds

A study by the Brain Research Institute at UZH reveals that early trauma leads to changes in blood metabolites - similarly in mice and humans.

15 Oct 2020

NIH grants 4D Nucleome award to support research by Gladstone scientists

The National Institutes of Health has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, PhD, and Katie Pollard, PhD.

15 Oct 2020

Mendelian randomization helps evaluate impact of circulating proteins in COVID-19

Researchers identify circulating proteins influencing COVID-19 susceptibility and severity by employing a large-scale two-sample Mendelian randomization (MR) study.

15 Oct 2020

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

In a recent paper available on the bioRxiv preprint server, US researchers show that individual particles of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) undergo structural destabilization at relatively mild but elevated temperatures – strengthening the case for coronavirus disease (COVID-19) resurgence in the winter.

15 Oct 2020

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

A large international consortium of almost 200 researchers from 14 leading institutions in six countries has studied three different coronaviruses - SARS-CoV-1, SARS-CoV-2, and MERS-CoV - with the aim of finding vulnerabilities shared by these three pathogens.

15 Oct 2020

Cloud-based tool can rapidly detect and track emerging pathogens

Published today in the journal GigaScience is a new open source, cloud-based tool called IDseq that makes it possible to rapidly detect, identify, and track emerging pathogens such as SARS-CoV-2.

15 Oct 2020

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision medicines to improve patient outcomes. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Nature Communications.

15 Oct 2020

Study shows how HGT can bend the rules of evolution

In a world first Monash University scientists have discovered that HGT can bend the rules of evolution. The discovery is outlined in a study published today in PNAS, which was led by ARC Future Fellow Dr Mike McDonald and PhD candidate Laura Woods, both from the Monash University School of Biological Sciences.

15 Oct 2020

Genome News and Research

Researchers find distinct effects of adversity in the genomes of men than women born preterm

Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

Precision epidemiology could help explain variability in COVID-19 symptoms

Study helps restore retinal and visual functions of mice models of inherited retinal disease

Researchers map the first draft sequence of human proteome

The connection between severe COVID-19 and white blood cell counts

Cleveland Clinic joins new Center for Integrated Multi-Modal and Multi-Scale Nucleome Research

Elevated birth weight is linked with atrial fibrillation later in life, shows study

New diagnostic test detects and identifies SARS-CoV-2 virus in less than five minutes

'Jumping genes' may frequently alter neural function

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Early trauma leads to changes in blood metabolites, study finds

NIH grants 4D Nucleome award to support research by Gladstone scientists

Mendelian randomization helps evaluate impact of circulating proteins in COVID-19

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

Researchers identify potential drugs that could be repurposed as pan-coronavirus treatments

Cloud-based tool can rapidly detect and track emerging pathogens

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Study shows how HGT can bend the rules of evolution

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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