Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Research opens new avenues for treating asthma and other inflammatory diseases

For decades, scientists have thought they understood the biochemical machinery that causes asthma-inflammation in the lungs that constricts airways and makes it hard to breathe.

23 Oct 2025

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

Biodesix, Inc., a leading diagnostics solutions company, today announced the signing of an expanded partnership agreement under which Biodesix will conduct the development, clinical validation, and regulatory submissions of in vitro diagnostic (IVD) assays to enable highly sensitive detection of multiple genomic markers focused on oncology applications, utilizing Bio-Rad's Droplet Digital™ PCR (ddPCR™) technology on Bio-Rad's QX600 platform.

23 Oct 2025

UC San Diego receives $6.2 million grant to establish REACH Center for Translational Science on Whole Person Health

The University of California San Diego School of Medicine's Centers for Integrative Health has received a five-year, $6.2 million grant from the National Center for Complementary and Integrative Health (NCCIH) at the National Institutes of Health (NIH) to establish the REACH Center for Translational Science on Whole Person Health.

22 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

21 Oct 2025

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

A new cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) shows that a drug that utilizes the body's immune system to target and eliminate cancer cells appeared to reduce the risk of distant metastases for an aggressive form of skin cancer when given immediately after surgery, but did not significantly reduce the overall risk of recurrence, which was a co-primary endpoint of the trial.

21 Oct 2025

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and amyloid-tau pathology through shared molecular pathways. The review highlights emerging therapies, targeting TLR4, GSK-3β, and metabolic dysfunction, that may mitigate alcohol-induced neurodegeneration.

20 Oct 2025

Social and environmental inequality linked to risk of Alzheimer’s

The study uncovers links between neighborhood disadvantage and Alzheimer's biomarkers, stressing the importance of addressing social inequalities in healthcare.

20 Oct 2025

Thymic health found to predict immunotherapy success in cancer patients

The health of the thymus - a key part of the body's immune system - is associated with cancer patients' outcomes to immune checkpoint inhibitor treatment, according to a ground-breaking international study reported at ESMO 2025.

16 Oct 2025

Uncovering a molecular weakness in Ewing sarcoma for targeted therapy

A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) to certain chemotherapy drugs, such as irinotecan.

16 Oct 2025

Blood test shows promise for faster ALS diagnosis

New research by UCLA Health has found a simple blood test could provide faster and more accurate diagnosis of ALS by measuring cell-free DNA.

15 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

Keensight Capital acquires majority stake in Bedfont® Scientific Ltd., a global leader in non-invasive breath analysis devices

Keensight Capital (“Keensight”), one of the leading private equity managers dedicated to pan-European Growth Buyou investments, today announced it has acquired a majority stake in Bedfont® Scientific Ltd. (“Bedfont”), which designs and manufactures non-invasive breath analysis medical devices.

From Bedfont® Scientific Ltd 15 Oct 2025

New wearable sensor tracks vitamin B6 levels in sweat

Vitamin B6, which is absorbed from a broad range of foods, helps bolster immune system function and neurotransmitters in the brain.

14 Oct 2025

Psychedelics could alter treatment paradigms for stress-related mental health conditions

A peer-reviewed viewpoint article published today in Psychedelics by Prof. Xiaohui Wang and colleagues examines the therapeutic potential of psychedelic substances for treating stress-related psychiatric disorders through novel neurobiological mechanisms.

14 Oct 2025

Rapid heart rate changes predict response to magnetic brain stimulation in depression

Researchers led by Dr. Roberto Goya-Maldonado at the University Medical Center Göttingen have identified a rapid physiological marker that predicts which patients with major depression will respond to magnetic brain stimulation therapy.

14 Oct 2025

CN Bio launches all-in-one Organ-on-a-chip system

CN Bio, a leading provider of benchtop Organ-on-a-chip (OOC) solutions that accelerate drug discovery and development, today announced the launch of PhysioMimix® Core.

14 Oct 2025

New advances improve cough detection in wearable health monitors

Researchers have improved the ability of wearable health devices to accurately detect when a patient is coughing, making it easier to monitor chronic health conditions and predict health risks such as asthma attacks.

13 Oct 2025

Digital test plus blood biomarker boosts accuracy of Alzheimer’s diagnosis in primary care

A Swedish-led study validated a self-administered digital cognitive test (BioCog) in primary care, showing it can accurately detect objective cognitive impairment before blood biomarkers are applied. When paired with a targeted amyloid blood test, this stepwise pathway outperformed standard assessments for diagnosing clinical Alzheimer’s disease.

12 Oct 2025

Biomarker News and Research

Further Reading

Research opens new avenues for treating asthma and other inflammatory diseases

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

UC San Diego receives $6.2 million grant to establish REACH Center for Translational Science on Whole Person Health

People with multiple sclerosis found to have dysbiotic oral microbiome

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Researchers develop a novel approach to monitor CD8⁺ T cell activity over time

Largest trial of adjuvant pembrolizumab in Merkel cell carcinoma reports key benefit

Heavy drinking fuels Alzheimer’s disease by igniting brain inflammation and protein damage

Social and environmental inequality linked to risk of Alzheimer’s

Thymic health found to predict immunotherapy success in cancer patients

Uncovering a molecular weakness in Ewing sarcoma for targeted therapy

Blood test shows promise for faster ALS diagnosis

Study links gut dysbiosis with severe steatosis in MASLD

Keensight Capital acquires majority stake in Bedfont® Scientific Ltd., a global leader in non-invasive breath analysis devices

New wearable sensor tracks vitamin B6 levels in sweat

Psychedelics could alter treatment paradigms for stress-related mental health conditions

Rapid heart rate changes predict response to magnetic brain stimulation in depression

CN Bio launches all-in-one Organ-on-a-chip system

New advances improve cough detection in wearable health monitors

Digital test plus blood biomarker boosts accuracy of Alzheimer’s diagnosis in primary care

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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