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G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even regulate our mood and immunity.

14 Oct 2020

Alternate primers for whole-genome SARS-CoV-2 sequencing

A new study published on the preprint server bioRxiv* in October 2020 describes the gap frequencies and positions in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and a set of alternative primers with a sequencing scheme to provide better genomic coverage and quality.

14 Oct 2020

Modification of DNA structure plays key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage.

14 Oct 2020

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

EuCanImage has been launched. This project from the Horizon 2020 program is coordinated by Karim Lekadir, Ramón y Cajal postdoctoral researcher at the Faculty of Mathematics and Computer Science.

13 Oct 2020

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

12 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Peer reviewers flag misleading studies on COVID-19

The preprints selected for review in Rapid Reviews: COVID-19 (RR:C19), an open-access overlay journal published by the MIT Press, cover a wide range of subjects, with peer reviewers finding a study that higher levels of cytokines IL-6 and IL-10 are associated with increased severity of COVID-19 is particularly noteworthy and could be useful in clinical care.

12 Oct 2020

New study may lead to more effective, personalized cancer immunotherapies

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

12 Oct 2020

Vaccines likely to be effective against SARS-CoV-2 D614G mutation

The emergence of the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutation D614G has raised many questions, including whether it will cause the virus to become resistant to the vaccines produced against earlier versions of the virus. A new study published in the journal npj Vaccines in October 2020 shows that this may be an unfounded fear.

11 Oct 2020

New initiative identifies key parameters underlying effective anti-tumor immunity

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

9 Oct 2020

UroCAD assay is better than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

9 Oct 2020

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

The banyan fig tree Ficus microcarpa is famous for its aerial roots, which sprout from branches and eventually reach the soil.

9 Oct 2020

Scientists recreate initial steps of HIV infection in a test tube

Accomplishing a feat that had been a pipe dream for decades, scientists have recreated in a test tube the first steps of infection by HIV (human immunodeficiency virus), the virus that causes AIDS (acquired immunodeficiency syndrome).

9 Oct 2020

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases - including cancer -, an area of research where progress is constantly being made.

9 Oct 2020

Mass production of SARS-CoV-2 ORF8 protein using a chemical-inducible system in tobacco BY-2 cells

Researchers from the Japan Advanced Institute of Science and Technology (JAIST) and Ishikawa Prefectural University, Japan, recently attempted to synthesize the ORF8 protein with the help of a chemical-inducible protein production system using tobacco BY-2 cells. This study has been published demonstrated in the preprint server, bioRxiv.

9 Oct 2020

Genome News and Research

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Alternate primers for whole-genome SARS-CoV-2 sequencing

Modification of DNA structure plays key role in the recovery phase after DNA damage

EuCanImage to build scalable cancer imaging platform for next-generation artificial intelligence in oncology

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Peer reviewers flag misleading studies on COVID-19

New study may lead to more effective, personalized cancer immunotherapies

Vaccines likely to be effective against SARS-CoV-2 D614G mutation

New initiative identifies key parameters underlying effective anti-tumor immunity

UroCAD assay is better than urine cytology in detecting bladder cancer

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

Scientists recreate initial steps of HIV infection in a test tube

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

Mass production of SARS-CoV-2 ORF8 protein using a chemical-inducible system in tobacco BY-2 cells

Exome sequencing sheds light on genetic causes of nonimmune hydrops fetalis

Scientists refine SARS-CoV-2 protein structures

Researchers track down two new relatives of rubella virus

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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