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PD-1 helps guide immune memory cells to the skin early during infection

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Researchers classify how specific genetic mutations correspond to rare disorders

The NF-κB signaling pathway plays a pivotal role in how our bodies fight infection, heal, and regulate inflammation. At the heart of this pathway is the NEMO protein, encoded by the IKBKG gene.

30 Jul 2025

Innovative nanopore system enables controlled DNA unzipping

DNA holds the instructions that make us who we are. If we want to read those instructions, say to understand our predisposition to genetic disorders, we need to carefully 'unzip' DNA's iconic double-helix structure.

30 Jul 2025

Analysis shows low pre-pregnancy glucose increases risk of preterm birth

An analysis of data from more than 4.7 million Chinese women showed that those who had low blood sugar levels prior to conception were more likely to have certain adverse pregnancy outcomes-such as their baby being born preterm or with low birth weight.

30 Jul 2025

Antiviral treatment shows no benefit for early Alzheimer’s patients

The idea that herpes infections trigger or contribute to Alzheimer's disease has been gaining favor among some scientists, raising hope that herpes treatments could slow progression of Alzheimer's symptoms among patients.

30 Jul 2025

Exercise-based cardiac rehab benefits atrial fibrillation

Exercise-based cardiac rehabilitation lessens the severity, frequency, and recurrence of the most common form of irregular heart rhythm, atrial fibrillation, or AF for short, finds a pooled data analysis of the available research, published online in the British Journal of Sports Medicine.

30 Jul 2025

Vanderbilt team explores functional β-cell enhancement for diabetes

If it has seemed like more people you know are developing diabetes, you are right. The diabetes epidemic is not called that for nothing: According to the American Diabetes Association, over 10 percent of the U.S. population-approximately 38.4 million people-had diabetes in 2021, and 1.2 million more people get diagnosed each year.

30 Jul 2025

Study debunks "No Nut November" claims: Abstinence shows no health benefits or harms

A new study in The Journal of Sexual Medicine found that participating in “No Nut November”, a month-long abstinence challenge, had no measurable effect on sexual well-being. The only significant difference was that participants reported higher sexual flexibility, likely reflecting a pre-existing trait.

29 Jul 2025

Oral cancer risk triples among individuals with cannabis use disorder

A recent study by researchers at the University of California San Diego School of Medicine has found that individuals with cannabis use disorder (CUD) are more than three times more likely to develop oral cancer within five years compared to those without CUD.

29 Jul 2025

Blood-based tests show promise for colorectal cancer screening but follow-up challenges persist

A study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found that while blood-based tests offer a more convenient option for colorectal cancer screening, only 49% of patients completed a follow-up colonoscopy within six months, and just 56% did so at any point during the two-year study period.

29 Jul 2025

The Mount Sinai Hospital named among nation’s top 20 for care excellence

The Mount Sinai Hospital, the flagship hospital of Mount Sinai Health System, was listed among the nation's top 20 hospitals for care excellence by U.S. News & World Report for 2025-26, marking the 10th consecutive year the hospital has been listed on the publication's "Honor Roll."

29 Jul 2025

Home-based brain stimulation system uses AI to enhance concentration

A personalized brain stimulation system powered by artificial intelligence (AI) that can safely enhance concentration from home has been developed by researchers from the University of Surrey, the University of Oxford and Cognitive Neurotechnology.

29 Jul 2025

Synergistic effects of radiation and immunotherapy boost anti-tumor immunity

Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose.

29 Jul 2025

Rising liver cancer rates highlight need for urgent action worldwide

The majority of liver cancer cases could be prevented by reducing levels of viral hepatitis, alcohol consumption and MASLD (metabolic dysfunction-associated steatotic liver disease – previously called non-alcoholic fatty liver disease), suggests an analysis as part of The Lancet Commission on liver cancer.

29 Jul 2025

Diabetes care model shows unequal benefits across racial groups

Background and goal: The Enhanced Primary Care Diabetes (EPCD) model is a nurse-led care delivery model that leverages multidisciplinary support to improve diabetes care quality in primary care settings.

29 Jul 2025

Study examines how often adults with opioid use disorder begin and stay on treatment

Opioid use disorder (OUD) medication treatment saves lives, yet fewer than one-third of people with OUD receive evidence-based treatment with medication.

29 Jul 2025

Mapping the role of family physicians in rural maternity care

This study explores the geographic distribution of family physicians providing maternity care and identifies opportunities for family physicians to expand access to maternity care.

29 Jul 2025

Body fat percentage outperforms BMI in predicting early mortality

Although body mass index (BMI) is widely used in clinics as the standard measure of body composition, it can potentially misclassify muscular individuals as overweight and miss cases of "normal-weight obesity," masking serious metabolic and heart disease risks.

29 Jul 2025

Gut microbial metabolites restore hormone-producing cells in obesity

New research from scientists at the Marshall University Joan C. Edwards School of Medicine reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.

29 Jul 2025