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Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

A recent research paper posted to the bioRxiv* preprint server demonstrated that a cocktail of two synergetic antibodies extensively neutralized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including Omicron BA.1 and BA.2.

1 May 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Probenecid shows activity against respiratory syncytial virus

A new study describes the antiviral activity of the approved drug probenecid against respiratory syncytial virus.

29 Apr 2022

Exploring happy hypoxia in COVID-19 patients

In a new study, researchers reported that silent hypoxia was not unique to COVID-19.

29 Apr 2022

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

A recent article published in the Med journal reported that the SARS-CoV-2 booster vaccinations enhance the SARS-CoV-2 Omicron sublineage neutralizations.

29 Apr 2022

Poor asthma control triggered by SARS-CoV-2

In a new study, researchers noted that COVID-19 could trigger poor pediatric asthma control.

29 Apr 2022

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Researchers surveilled coronaviruses found in bats via targeted genomic sequencing.

29 Apr 2022

Children treated with antibiotics have abundant fungal microbiota in the gut, study reveals

A study recently completed at the University of Helsinki revealed that the fungal microbiota in the gut is more abundant and diverse in children treated with antibiotics compared with the control group even six weeks following the start of the antibiotic course.

29 Apr 2022

Study highlights the need to improve clinical management of Malawian children with low blood sugar or blood oxygen levels

A new study in rural Malawi underscores the need for better clinical management of severely ill children with very low blood sugar or blood oxygen levels.

29 Apr 2022

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Researchers discussed the validity of the equation derived by Khoury et al. and reported by Muena et al. regarding the immunological correlate of protection to predict the efficacy of new coronavirus vaccines in a real-world setting.

29 Apr 2022

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did not significantly reduce patients' risk of organ failure, kidney problems, or death compared with placebo, although numerically fewer participants treated with dapagliflozin experienced these outcomes. The findings are published in CJASN.

29 Apr 2022

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Researchers examined the characteristics and outcomes of COVID-19 in immunocompromised patients.

29 Apr 2022

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

In a new study, researchers described their self-designed chimeric receptor-binding domain-dimer vaccine approach to adapt SARS-CoV-2 variants of concern and variants of interest.

29 Apr 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

A recent study demonstrated that the phytochemical curcumin is a potent therapeutic prospect against the SARS-CoV-2 Omicron variant

29 Apr 2022

Improving Medical Communication through Social Media

News-Medical interviews Dr. Benjamin Schmidt about using social media to highlight different perspectives in the medical community and improve communication between patients and doctors.

29 Apr 2022

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

A new study published in Marine Drugs evaluated the inhibitory effect of three polysaccharides, crude polysaccharide from Hizikia fusiforme (CPHF), crude polysaccharide from Sargassum horneri (CPSH), and crude polysaccharide from abalone viscera (CPAV) on the propagation of SARS-CoV-2 in vitro.

28 Apr 2022

Study investigates intestinal ischemia in COVID-19 patients

A team of Italian scientists has presented case reports of five coronavirus disease 2019 (COVID-19) patients undergoing emergency surgery for intestinal ischemia.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Respiratory News and Research

Antibody cocktail shows synergetic effects against SARS-CoV-2 Omicron in vitro and in vivo

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Probenecid shows activity against respiratory syncytial virus

Exploring happy hypoxia in COVID-19 patients

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Poor asthma control triggered by SARS-CoV-2

Study evaluates hybridization probe capture for enriching coronavirus genomic material in bat oral and rectal swabs

Children treated with antibiotics have abundant fungal microbiota in the gut, study reveals

Study highlights the need to improve clinical management of Malawian children with low blood sugar or blood oxygen levels

Identifying the immunological correlate of protection to predict the efficacy of new coronavirus vaccines

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

Clinical characteristics of immunocompromised patients infected with the SARS-CoV-2 Omicron variant

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

Improving Medical Communication through Social Media

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

Study investigates intestinal ischemia in COVID-19 patients

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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