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Outpatient therapy offers hope for young eating disorder patients after hospitalization

Eating disorders affect more than 5% of young people, and they have one of the highest mortality rates of any mental illness.

28 Jul 2025

New study links surrogacy to higher risk of mental illness

People who are gestational carriers (or "surrogates") appear more likely to be diagnosed with a new mental illness during and after pregnancy, according to new research from ICES, McGill University, and the Research Institute of the McGill University Health Centre.

28 Jul 2025

Global vaccination effort saved 2.5 million lives from SARS-CoV-2

Thanks to vaccinations against SARS-CoV-2 in the period 2020-2024 2.533 million deaths were prevented at global level, one death was avoided for every 5,400 doses of vaccine administered. The 82% of the lives saved by vaccines involved people vaccinated before encountering the virus, 57% during the Omicron period, and 90% involved people aged 60 years and older. In all, vaccines have saved 14.8 million years of life (one year of life saved for 900 doses of vaccine administered).

28 Jul 2025

Study finds past H1N1 exposure shields animals from deadly H5N1

Preexisting immunity to the 2009 H1N1 influenza virus provided near-complete protection against severe H5N1 disease and transmission in ferrets, even after high-dose exposure. In contrast, H3N2 immunity alone offered only partial, inconsistent protection.

28 Jul 2025

New model predicts mRNA protein production, accelerating drug and vaccine discovery

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types. The new advance, developed through an academic-industrial partnership between The University of Texas at Austin and Sanofi, helps predict how much protein cells will produce, which can minimize the need for trial-and-error experimentation, accelerating the next generation of mRNA therapeutics.

26 Jul 2025

Research uncovers ME/CFS's systemic impact for targeted therapies

Millions suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition often overlooked due to the lack of diagnostic tools, may be closer to personalized care, according to new research that shows how the disease disrupts interactions between the microbiome, immune system, and metabolism.

26 Jul 2025

New study shows potent effects of desert berry extract (NRK-C)

The global diabetes epidemic continues its relentless march, with projections suggesting 750 million sufferers by 2045. While current medications help control symptoms, they often come with undesirable side effects and don't address the root causes of metabolic dysfunction. The search for better solutions has turned scientists toward natural drugs, where traditional remedies may hold untapped potential.

26 Jul 2025

Researchers pinpoint PRMT5 as a promising target for cancer drugs

A potential target for experimental drugs that block PRMT5 - a naturally occurring enzyme some tumors rely more on for survival - has been identified by researchers with the Fralin Biomedical Research Institute's Cancer Research Center in Washington, D.C.

26 Jul 2025

Study reveals stigmatizing responses in LLMs for addiction-related queries

As artificial intelligence is rapidly developing and becoming a growing presence in healthcare communication, a new study addresses a concern that large language models (LLMs) can reinforce harmful stereotypes by using stigmatizing language.

26 Jul 2025

VCU Massey pioneers clinical trial of novel GGT-1 inhibitor PTX-100

VCU Massey Comprehensive Cancer Center is the first site in the United States to be activated in a global Phase 2a clinical trial evaluating PTX-100 (AKA GGTI-2418), a first-in-class small molecule inhibitor of geranylgeranyl transferase-1 (GGT-1), for the treatment of cutaneous T-cell lymphoma (CTCL), a rare and often treatment-resistant T-cell lymphoma.

26 Jul 2025

Discovery of TAF1's role could revolutionize cancer treatment

A new study led by Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, shows how a key molecule regulates the generation of new blood cells, a process called hematopoiesis that goes awry in cancer. The findings have the potential to lead to new therapeutic strategies targeting the molecule, a regulator of gene activity called TAF1.

26 Jul 2025

Addressing avoidable hospitalizations in terminally ill nursing home residents

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

25 Jul 2025

New method uses magnetism for targeted drug delivery

Researchers have demonstrated that microscopic drug delivery containers can be magnetically steered to their targets, advancing the development of precision medicine for treating diseases such as cancer.

25 Jul 2025

Scientists open new atlas of genetic diversity with advanced sequencing

A global team mapped over 100,000 structural variants in human genomes by applying Oxford Nanopore long-read sequencing and a novel graph-based analytical approach to samples from 26 populations. The study reveals the extraordinary complexity and diversity of human DNA, providing an open-access atlas that will accelerate discoveries in genetic disease and human evolution.

24 Jul 2025

Commonly used type 2 diabetes medication linked to higher rate of heart-related conditions

New research from investigators at Mass General Brigham suggests that a commonly used type 2 diabetes medication is linked to a higher rate of heart-related conditions compared to medications that hit other targets.

24 Jul 2025

IRF-5 identified as key to preventing immune cell exhaustion

In fighting chronic infections or certain cancers, CD8+ T cells-the immune system's frontline soldiers-eventually become exhausted. They lose effectiveness and respond less efficiently to threats.

24 Jul 2025

Expanding mastectomy access could prevent more breast cancer cases

More women at higher risk of breast cancer should be offered a mastectomy, according to a new study led by researchers at the London School of Hygiene & Tropical Medicine (LSHTM) and Queen Mary, University of London.

24 Jul 2025

Study finds benefits of personalized ventilation in ICU care

A seven-year international, multi-centre clinical trial led by London Health Sciences Centre Research Institute (LHSCRI) and St. Michael's Hospital, a site of Unity Health Toronto, has found that a new ventilation mode called proportional assist ventilation (PAV+™) could improve outcomes for patients in the intensive care unit (ICU) who require help breathing.

24 Jul 2025

Billing codes in big data often misidentify diagnoses

Use of billing codes in big data sets to find diagnoses can result in up to two-thirds of cases being mistakenly identified, new UCLA-led research finds.

24 Jul 2025