Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Smartphone microscopes could improve detection of skin cancer in developing countries

Everyone knows smartphones can be used as calendars, calculators, radios and cameras. But, did you know they can also be used as microscopes that have the potential to save lives? They are called smartphone microscopes and dermatologists at The University of Texas Health Science Center at Houston think these devices could improve the detection of skin cancer in developing countries.

16 Mar 2016

Real-time imaging method may lead to improved stroke care

According to the American Heart Association, ischemic strokes account for nearly 90 percent of all strokes. They occur when a blocked artery prevents blood from getting to the brain and usually result in long-term disability or death. Now, a team of researchers led by the University of Missouri School of Medicine has developed a new, real-time method of imaging molecular events after strokes - a finding that may lead to improved care for patients.

15 Mar 2016

New drug could transform treatment of metastatic triple negative breast cancer

A team of investigators from Houston Methodist Research Institute may have transformed the treatment of metastatic triple negative breast cancer by creating the first drug to successfully eliminate lung metastases in mice.

15 Mar 2016

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Addition of lapatinib to trastuzumab improves responses in women with newly diagnosed, HER2-positive breast cancer who receive the combination prior to undergoing surgery, suggests research.

14 Mar 2016

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

Many Chamorro villagers on the island of Guam perished from a puzzling paralytic disease that combines aspects of ALS, Alzheimer's, and Parkinson's disease.

From Huron Technologies 14 Mar 2016

New evidence-based guideline to tackle synoptic reporting of bone marrow data

Clinicians and patients alike will benefit as the Pathology and Laboratory Quality Center of the College of American Pathologists releases a new evidence-based guideline that tackles the complexities of reporting findings from bone marrow specimens.

14 Mar 2016

NIH-funded investigators develop therapeutic compound effective against malaria

An international team that includes NIH-funded researchers at Stanford University has developed a therapeutic compound that is effective in inhibiting Plasmodium falciparum, one of five species of parasite that infects people with malaria, and the strain which causes the highest number of malaria deaths.

13 Mar 2016

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Researchers have shown for the first time that it is possible to use a multi-gene test to identify patients with early breast cancer who can be spared chemotherapy and who will still be alive and well five years after diagnosis.

11 Mar 2016

Research uncovers biological differences between male, female breast cancers

Male breast cancer (Male BC) has important biological differences that distinguish it from female breast cancer, but to date these have been little studied and Male BC patients have been excluded from many clinical trials in breast cancer.

11 Mar 2016

Latest and final review of health problems related to Agent Orange exposure during Vietnam War

The latest and final in a series of congressionally mandated biennial reviews of the evidence of health problems that may be linked to exposure to Agent Orange and other herbicides used during the Vietnam War changed the categorization of health outcomes for bladder cancer, hypothyroidism, and spina bifida and clarified the breadth of the previous finding for Parkinson's disease.

11 Mar 2016

New drug combination treatment makes breast cancer tumours disappear in just 11 days

Approximately a quarter of women with HER2 positive breast cancer, who were treated with a combination of the targeted drugs lapatinib and trastuzumab before surgery and chemotherapy, saw their tumours shrink significantly or even disappear, according to results from a clinical trial.

11 Mar 2016

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

Path Links upgraded to digital pathology to provide highest quality cancer diagnostic services

Path Links, the single managed NHS clinical pathology service operating across Lincolnshire, has upgraded to digital pathology to continue its focus on providing the highest quality diagnostic services for Northern Lincolnshire & Goole NHS Foundation Trust, United Lincolnshire Hospitals NHS Trust and 186 General Practices across the county.

10 Mar 2016

CWRU researcher to customize tobacco mosaic virus to treat human cancers

A Case Western Reserve University researcher has been awarded more than $3 million in federal and foundation grants to turn common plant viruses into cancer sleuths and search-and-destroy emissaries.

10 Mar 2016

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). Although 5-HT is predominantly known as a neurotransmitter within the central nervous system, new evidence points to additional important functions for serotonin in the periphery.

10 Mar 2016

Discovery may provide potential target for new therapies to treat bipolar disorder

Bipolar disorder, which affects nearly eight million Americans, takes a toll not only on patients, but also on their families and communities.

10 Mar 2016

Novel nanoparticle technology can decipher protein structures and help access drug targets

Researchers at Karolinska Institutet, Sweden, have developed a nanoparticle technology that can be used to stabilise membrane proteins so that their structure can be studied in a lipid environment. The method, described in Nature Methods, makes it possible to access drug targets that previously could not be investigated and therefore potentially allows for the development of novel drugs, therapeutic antibodies and vaccines.

9 Mar 2016

Mayo Clinic develops 'The ABCs of Influenza' flash cards

Influenza is a serious viral infection that causes illness, hospitalizations and thousands of deaths every year in the U.S. Mayo Clinic recommends getting a vaccine each year to prevent illness and protect the people around you.

9 Mar 2016

Consuming green tea with dietary iron may lessen health benefits of green tea

Green tea is touted for its many health benefits as a powerful antioxidant, but experiments in a laboratory mouse model of inflammatory bowel disease suggest that consuming green tea along with dietary iron may actually lessen green tea's benefits.

9 Mar 2016

Novel mechanism identified to protect the brain from many neurodegenerative conditions

Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.

8 Mar 2016

Pathology News and Research

Further Reading

Smartphone microscopes could improve detection of skin cancer in developing countries

Real-time imaging method may lead to improved stroke care

New drug could transform treatment of metastatic triple negative breast cancer

Preoperative lapatinib plus trastuzumab elicits response in HER2-positive breast cancer

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox

New evidence-based guideline to tackle synoptic reporting of bone marrow data

NIH-funded investigators develop therapeutic compound effective against malaria

Multi-gene test can help identify early breast cancer patients who can safely be spared chemotherapy

Research uncovers biological differences between male, female breast cancers

Latest and final review of health problems related to Agent Orange exposure during Vietnam War

New drug combination treatment makes breast cancer tumours disappear in just 11 days

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

Path Links upgraded to digital pathology to provide highest quality cancer diagnostic services

CWRU researcher to customize tobacco mosaic virus to treat human cancers

Study reveals direct regulatory role of serotonin in rheumatoid arthritis

Discovery may provide potential target for new therapies to treat bipolar disorder

Novel nanoparticle technology can decipher protein structures and help access drug targets

Mayo Clinic develops 'The ABCs of Influenza' flash cards

Consuming green tea with dietary iron may lessen health benefits of green tea

Novel mechanism identified to protect the brain from many neurodegenerative conditions

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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