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Scientists have more evidence of why clear margins in breast cancer surgery are such good news

When a breast cancer tumor is removed with no signs of cancer left behind, it's great news for patients, and now scientists have more evidence of why.

1 Apr 2019

Single dose long lasting opioid antidote on the horizon

Recent reports have shown a 1,000 percent rise in opioid abuse (especially synthetic drug Fentanyl) in the United States over the past one decade. In 2017 for example there have been 47,000 deaths attributed to opioid overdose says the US Centre for Disease Control and Prevention (CDC).

31 Mar 2019

Neuroscientists develop new model to trial preventative treatments for schizophrenia

Neuroscientists at The University of Queensland have developed a new animal model of schizophrenia that will enable researchers around the world to better understand the disease and develop new treatments.

30 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

European Research Council awards grant for research on insulin-producing cells

The ERC Advanced Grant is one of the most prestigious funding programmes for research in Europe. Per-Olof Berggren, professor of experimental endocrinology at Karolinska Institutet, is now awarded this grant for the second time.

28 Mar 2019

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor.

28 Mar 2019

New medication increases muscle and bone mass in mice

It is common knowledge that as people grow older they lose a large part of their muscle mass - and neither are their bones what they once were. Researchers from Aarhus University, Denmark, working together with researchers at Erasmus Medical Center in Rotterdam have now studied a new group of medication which could prove beneficial for the elderly and the chronically ill who suffer a loss of bone- and muscle mass.

28 Mar 2019

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Critical Path Institute announced today that a formal consultation between its Predictive Safety Testing Consortium and Japan's Pharmaceuticals and Medical Devices Agency has resulted in an agreement on a first-of-its-kind approach to compare the levels of eight novel urinary kidney safety biomarkers in healthy Japanese volunteers to data collected on these same biomarkers in healthy Western volunteers in a bridging study.

27 Mar 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019

Synthetic alcohol substitute could make hangovers a thing of the past

Professor David Nutt is aiming to make hangovers a thing of the past by introducing a synthetic alcohol alternative named "alcosynth".

27 Mar 2019

Cambrex doubles liquid packaging capacity and weekly output at its Québec facility

Cambrex Corporation, the leading small molecule company providing drug substance, drug product and analytical services across the entire drug lifecycle, today announced it will double the liquid packaging capacity and weekly output at its Mirabel, Québec site in Canada with the addition of a cGMP packaging line and a new filler on the existing packaging line.

27 Mar 2019

Researchers unravel biomechanics of Ebola virus-host cell adhesion

It was recently reported that the number of Ebola cases in the Democratic Republic of Congo has surpassed 1,000, making it the second-worst outbreak in history after the 2014 outbreak in West Africa in which 29,000 people were infected and more than 11,000 died.

27 Mar 2019

Discovery could lead to new drugs for pain conditions

If a particular protein is missing during the fetal stage, no neurons develop that convey pain, temperature and itch, a study from Karolinska Institutet in Sweden published in the journal Cell Reports shows. The discovery can eventually lead to new drugs for pain conditions.

27 Mar 2019

New survey indicates need of attention to neglected tropical diseases

Although neglected diseases account for 11% of the global disease burden, they are targeted by only a small proportion of the new drugs developed every year.

22 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Brain process common to sleep and aging discovered

Oxford University researchers have discovered a brain process common to sleep and ageing in research that could pave the way for new treatments for insomnia.

22 Mar 2019